Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Heather D. VanGuilder"'
Autor:
Heather D. VanGuilder, Julie A. Farley, Han Yan, Colleen A. Van Kirk, Matthew Mitschelen, William E. Sonntag, Willard M. Freeman
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 201-212 (2011)
Age-related cognitive decline occurs without frank neurodegeneration and is the most common cause of memory impairment in aging individuals. With increasing longevity, cognitive deficits, especially in hippocampus-dependent memory processes, are incr
Externí odkaz:
https://doaj.org/article/1167c0ebb88a4dd7b5bb1f5723e095d0
Publikováno v:
BioTechniques, Vol 44, Iss 5, Pp 619-626 (2008)
Following its invention 25 years ago, PCR has been adapted for numerous molecular biology applications. Gene expression analysis by reverse-transcription quantitative PCR (RT-qPCR) has been a key enabling technology of the post-genome era. Since the
Externí odkaz:
https://doaj.org/article/de393bd33d7c4fb3b07658f612a88f65
Publikováno v:
Cellular and Molecular Neurobiology. 33:483-488
The myelin-associated inhibitor/Nogo-66 receptor 1 (NgR1) pathway directly functions in negative modulation of structural and electrophysiological synaptic plasticity. A previous study has established an important role of NgR1 pathway signaling in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61815a99429c4fce16e244c7628cde3e
https://doi.org/10.1007/s10571-013-9929-4
https://doi.org/10.1007/s10571-013-9929-4
Autor:
Junie P. Warrington, Vijay P. Kale, Jacob M. Serfass, Colleen A. Van Kirk, Willard M. Freeman, Matthew Mitschelen, Julie A. Farley, Heather D. VanGuilder Starkey, Song Han, Georgina V. Bixler, William E. Sonntag, Caesar G. Imperio, Han Yan
Publikováno v:
Journal of Molecular Neuroscience. 48:111-126
The hippocampus undergoes changes with aging that impact neuronal function, such as synapse loss and altered neurotransmitter release. Nearly half of the aged population also develops deficits in spatial learning and memory. To identify age-related h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143676fa92f54286d3279f6a72da5511
https://doi.org/10.1007/s12031-012-9783-8
https://doi.org/10.1007/s12031-012-9783-8
Publikováno v:
Journal of Neurochemistry. 121:77-98
Impairment of cognitive functions including hippocampus-dependent spatial learning and memory affects nearly half of the aged population. Age-related cognitive decline is associated with synaptic dysfunction that occurs in the absence of neuronal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a82e2a24ea621dcbbf181d33615b36
https://doi.org/10.1111/j.1471-4159.2012.07671.x
https://doi.org/10.1111/j.1471-4159.2012.07671.x
Autor:
Colleen A. Van Kirk, Han Yan, Matthew Mitschelen, Heather D. VanGuilder, Willard M. Freeman, William E. Sonntag, Julie A. Farley
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 201-212 (2011)
Age-related cognitive decline occurs without frank neurodegeneration and is the most common cause of memory impairment in aging individuals. With increasing longevity, cognitive deficits, especially in hippocampus-dependent memory processes, are incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd822a26fc3cb1c33f931a72213d93fb
https://doi.org/10.1016/j.nbd.2011.03.012
https://doi.org/10.1016/j.nbd.2011.03.012
Publikováno v:
Drug and Alcohol Dependence. 107:11-22
The number of discovery proteomic studies of drug abuse has begun to increase in recent years, facilitated by the adoption of new techniques such as 2D-DIGE and iTRAQ. For these new tools to provide the greatest insight into the neurobiology of addic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1287da69582c8ca753e580e92033add3
https://doi.org/10.1016/j.drugalcdep.2009.10.001
https://doi.org/10.1016/j.drugalcdep.2009.10.001
Autor:
Alistair J. Barber, Heather D. VanGuilder, Thomas W. Gardner, Kruti M. Patel, Robert M. Brucklacher, Sarah K. Bronson, Kathryn F. LaNoue, Scot R. Kimball, Willard M. Freeman, Cheng-mao Lin, David A. Antonetti, Georgina V. Bixler
Publikováno v:
The Pharmacogenomics Journal. 10:385-395
Biomarkers that can be measured in preclinical models in a high-throughput, reproducible manner offer the potential to increase the speed and efficacy of drug development. Development of therapeutic agents for many conditions is hampered by the limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc3d6dd8d8a7775430b95fcbdbb11f7
https://doi.org/10.1038/tpj.2009.60
https://doi.org/10.1038/tpj.2009.60
Autor:
Rhona W. Ellis, Willard M. Freeman, Robert M. Brucklacher, Kruti M. Patel, Heather D. VanGuilder, Alistair J. Barber
Publikováno v:
European Journal of Neuroscience. 28:1-11
Diabetic retinopathy can result in vision loss and involves progressive neurovascular degeneration of the retina. This study tested the hypothesis that diabetes decreases the retinal expression of presynaptic proteins involved in synaptic function. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ca4b8ed64486eee59a42e9a1467a31f
https://doi.org/10.1111/j.1460-9568.2008.06322.x
https://doi.org/10.1111/j.1460-9568.2008.06322.x
Autor:
Sarah K. Bronson, Heather D. VanGuilder Starkey, Wendy Dunton, Georgina V. Bixler, Willard M. Freeman, Dustin R. Masser
Publikováno v:
Experimental eye research. 125
Diabetic retinopathy is one of the leading causes of blindness in developed countries, and a majority of patients with type I and type II diabetes will develop some degree of vision loss despite blood glucose control regimens. The effects of differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c06dfc3b3553279349f800c9ef58ba
https://pubmed.ncbi.nlm.nih.gov/24931083
https://pubmed.ncbi.nlm.nih.gov/24931083