Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Heather D Hickman"'
Autor:
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Joel D Fleegle, Felipe Gomez, NIAID/DIR Tuberculosis Imaging Program, Sydnee T Gould, Cyril Le Nouën, Xueqiao Liu, Tracey L Burdette, Nicole L Garza, Bernard A P Lafont, Kelsie Brooks, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Alessandro Sette, Heather D Hickman, Ursula J Buchholz, Reed F Johnson, Jason M Brenchley, James P Oberman, Artur T L Quieroz, Bruno B Andrade, Laura E Via, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012339 (2024)
The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2 infection is incompletely understood. Here we examine the roles of the prototypic pro- and anti-inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of
Externí odkaz:
https://doaj.org/article/4f2fca22c4d14a298492237eba187e8e
Autor:
Mary K McCarthy, Glennys V Reynoso, Emma S Winkler, Matthias Mack, Michael S Diamond, Heather D Hickman, Thomas E Morrison
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008292 (2020)
Humoral immune responses initiate in the lymph node draining the site of viral infection (dLN). Some viruses subvert LN B cell activation; however, our knowledge of viral hindrance of B cell responses of important human pathogens is lacking. Here, we
Externí odkaz:
https://doaj.org/article/b5c53111380647c4b4471c64645a05a5
Autor:
Stephanie S Cush, Glennys V Reynoso, Olena Kamenyeva, Jack R Bennink, Jonathan W Yewdell, Heather D Hickman
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005493 (2016)
Skin infection with the poxvirus vaccinia (VV) elicits a powerful, inflammatory cellular response that clears virus infection in a coordinated, spatially organized manner. Given the high concentration of pro-inflammatory effectors at areas of viral i
Externí odkaz:
https://doaj.org/article/c142891839534da5bbde6d2ae883f015
Autor:
Javier G Magadán, Meghan O Altman, William L Ince, Heather D Hickman, James Stevens, Aaron Chevalier, David Baker, Patrick C Wilson, Rafi Ahmed, Jack R Bennink, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004204 (2014)
Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA stem is highly conserved between influenza virus strains, HA stem-reactive antibodies
Externí odkaz:
https://doaj.org/article/74024ffa48a944a1a6108bc9315387d3
Autor:
Jun P. Hong, Glennys V. Reynoso, Prabhakar S. Andhey, Amanda Swain, Jackson S. Turner, Adrianus C.M. Boon, Florian Krammer, Ali H. Ellebedy, Fabio Zanini, Maxim Artyomov, Heather D. Hickman, Michael S. Diamond
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100035- (2020)
Summary: CD137 is a costimulatory receptor expressed on natural killer cells, T cells, and subsets of dendritic cells. An agonistic monoclonal antibody (mAb) against CD137 has been used to reduce tumor burden or reverse autoimmunity in animal models
Externí odkaz:
https://doaj.org/article/1ffb03a736134680a4a3604723f38be8
Autor:
Chad H. Hogan, Shana M. Owens, Glennys V. Reynoso, Varvara Kirillov, Thomas J. Meyer, Monika A. Zelazowska, Bin Liu, Xiaofan Li, Aniska Chikhalya, Qiwen Dong, Camille Khairallah, Nancy C. Reich, Brian Sheridan, Kevin M. McBride, Patrick Hearing, Heather D. Hickman, J. Craig Forrest, Laurie T. Krug
Publikováno v:
bioRxiv
Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor STAT3. To better understand the role of STAT3 during gammaherpesvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a9e019c03ad97884212e0e6c06ef35
https://europepmc.org/articles/PMC10055336/
https://europepmc.org/articles/PMC10055336/
Autor:
Heather D. Hickman, Sophia M. Vrba
Publikováno v:
Immunol Rev
The past decade has seen near continual global public health crises caused by emerging viral infections. Extraordinary increases in our knowledge of the mechanisms underlying successful antiviral immune responses in animal models and during human inf
Autor:
Amy P. Hsu, Agnieszka Korzeniowska, Cynthia C. Aguilar, Jingwen Gu, Eric Karlins, Andrew J. Oler, Gang Chen, Glennys V. Reynoso, Joie Davis, Alexandria Chaput, Tao Peng, Ling Sun, Justin B. Lack, Derek J. Bays, Ethan R. Stewart, Sarah E. Waldman, Daniel A. Powell, Fariba M. Donovan, Jigar V. Desai, Nima Pouladi, Debra A. Long Priel, Daisuke Yamanaka, Sergio D. Rosenzweig, Julie E. Niemela, Jennifer Stoddard, Alexandra F. Freeman, Christa S. Zerbe, Douglas B. Kuhns, Yves A. Lussier, Kenneth N. Olivier, Richard C. Boucher, Heather D. Hickman, Jeffrey Frelinger, Joshua Fierer, Lisa F. Shubitz, Thomas L. Leto, George R. Thompson, John N. Galgiani, Michail S. Lionakis, Steven M. Holland
Publikováno v:
JCI insight, vol 7, iss 22
Disseminated coccidioidomycosis (DCM) is caused by Coccidioides, pathogenic fungi endemic to the southwestern United States and Mexico. Illness occurs in approximately 30% of those infected, less than 1% of whom develop disseminated disease. To addre
Autor:
Mina O. Seedhom, Devin Dersh, Jaroslav Holly, Mariana Pavon-Eternod, Jiajie Wei, Matthew Angel, Lucas Shores, Alexandre David, Jefferson Santos, Heather D. Hickman, Jonathan W. Yewdell
Rapid lymphocyte cell division places enormous demands on the protein synthesis machinery. Flow cytometric measurement of puromycylated ribosome-associated nascent chains after treating cells or mice with translation initiation inhibitors reveals tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75b17bf20d68718859e2f05879532d0
https://doi.org/10.1101/2022.10.31.514539
https://doi.org/10.1101/2022.10.31.514539
Autor:
Glennys V. Reynoso, David N. Gordon, Anurag Kalia, Cynthia C. Aguilar, Courtney S. Malo, Maya Aleshnick, Kimberly A. Dowd, Christian R. Cherry, John P. Shannon, Sophia M. Vrba, Sonia Maciejewski, Kenichi Asano, Theodore C. Pierson, Heather D. Hickman
SummaryZika virus (ZIKV) is an arthopod-vectored flavivirus that disseminates from the infection site into peripheral tissues, where it can elicit virus-induced pathology. To move through the body, ZIKV is thought to exploit the mobility of myeloid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf7cb6355330cc2a1115c42ea6603d3
https://doi.org/10.1101/2022.09.20.508424
https://doi.org/10.1101/2022.09.20.508424