Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heather Branscome"'
Autor:
Jessica Hindle, Anastasia Williams, Yuriy Kim, Dongsung Kim, Kajal Patil, Pooja Khatkar, Quinn Osgood, Collin Nelson, David A. Routenberg, Marissa Howard, Lance A. Liotta, Fatah Kashanchi, Heather Branscome
Publikováno v:
Cells, Vol 13, Iss 10, p 861 (2024)
As the economic burden associated with vision loss and ocular damage continues to rise, there is a need to explore novel treatment strategies. Extracellular vesicles (EVs) are enriched with various biological cargo, and there is abundant literature s
Externí odkaz:
https://doaj.org/article/b8fe702caf0a4c559e23f24d9cfeaacb
Autor:
Heather Branscome, Pooja Khatkar, Sarah Al Sharif, Dezhong Yin, Sheela Jacob, Maria Cowen, Yuriy Kim, James Erickson, Christine A. Brantner, Nazira El-Hage, Lance A. Liotta, Fatah Kashanchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-27 (2022)
Abstract HIV-1 remains an incurable infection that is associated with substantial economic and epidemiologic impacts. HIV-associated neurocognitive disorders (HAND) are commonly linked with HIV-1 infection; despite the development of combination anti
Externí odkaz:
https://doaj.org/article/932006a4711b41b492fc5a193958ded7
Autor:
Anastasia Williams, Pooja Khatkar, Heather Branscome, Yuriy Kim, James Erickson, Mohammad-Ali Jenabian, Cecilia T. Costiniuk, Fatah Kashanchi
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1147 (2023)
Currently, there is no cure for human immunodeficiency virus type 1 (HIV-1) infection. However, combined antiretroviral therapy (cART) aids in viral latency and prevents the progression of HIV-1 infection into acquired immunodeficiency syndrome (AIDS
Externí odkaz:
https://doaj.org/article/99707bc1f25c452fabfd7f2d4bac3a97
Autor:
Marissa Howard, James Erickson, Zachary Cuba, Shawn Kim, Weidong Zhou, Purva Gade, Rachel Carter, Kelsey Mitchell, Heather Branscome, Daivik Siddhi, Fatimah Alanazi, Yuriy Kim, Robyn P. Araujo, Amanda Haymond, Alessandra Luchini, Fatah Kashanchi, Lance A. Liotta
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract We characterized the in vivo interstitial fluid (IF) content of extracellular vesicles (EVs) using the GFP‐4T1 syngeneic murine cancer model to study EVs in‐transit to the draining lymph node. GFP labelling confirmed the IF EV tumour cel
Externí odkaz:
https://doaj.org/article/e005fbbe87c040998042b508de07e1d0
Autor:
Daniel O. Pinto, Sarah Al Sharif, Gifty Mensah, Maria Cowen, Pooja Khatkar, James Erickson, Heather Branscome, Thomas Lattanze, Catherine DeMarino, Farhang Alem, Ruben Magni, Weidong Zhou, Sandrine Alais, Hélène Dutartre, Nazira El-Hage, Renaud Mahieux, Lance A. Liotta, Fatah Kashanchi
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-27 (2021)
Abstract Background The Human T-cell Lymphotropic Virus Type-1 (HTLV-1) is a blood-borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). HTLV-1 has curre
Externí odkaz:
https://doaj.org/article/4364e98badb6462b9f29686cdbb50650
Autor:
Heather Branscome, Siddhartha Paul, Dezhong Yin, Nazira El-Hage, Emmanuel T. Agbottah, Mohammad Asad Zadeh, Lance A. Liotta, Fatah Kashanchi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neurodegeneration is a hallmark of many diseases and disorders of the central nervous system (CNS). High levels of neuroinflammation are often associated with irreparable damage to CNS cells due to the dysregulation of signaling cascades that are una
Externí odkaz:
https://doaj.org/article/2bd3d48897f84568b810811c4b73b291
Autor:
Catherine DeMarino, Maria Cowen, Pooja Khatkar, Bianca Cotto, Heather Branscome, Yuriy Kim, Sarah Al Sharif, Emmanuel T. Agbottah, Weidong Zhou, Cecilia T. Costiniuk, Mohammad-Ali Jenabian, Cohava Gelber, Lance A. Liotta, Dianne Langford, Fatah Kashanchi
Publikováno v:
Cells, Vol 11, Iss 4, p 723 (2022)
Of the 37.9 million individuals infected with human immunodeficiency virus type 1 (HIV-1), approximately 50% exhibit HIV-associated neurocognitive disorders (HAND). We and others previously showed that HIV-1 viral RNAs, such as trans-activating respo
Externí odkaz:
https://doaj.org/article/14747576254a438aaf3d3ab788c2d5d1
Autor:
Daniel O. Pinto, Catherine DeMarino, Michelle L. Pleet, Maria Cowen, Heather Branscome, Sarah Al Sharif, Jennifer Jones, Helene Dutartre, Benjamin Lepene, Lance A. Liotta, Renaud Mahieux, Fatah Kashanchi
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Human T-cell leukemia virus-1 (HTLV-1) is a neglected and incurable retrovirus estimated to infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection rates of more than 40%, suggesting a potential evolution of the
Externí odkaz:
https://doaj.org/article/af288fdff8204397bc151f3b2423b3f2
Autor:
Yuriy Kim, Gifty A. Mensah, Sarah Al Sharif, Daniel O. Pinto, Heather Branscome, Sowmya V. Yelamanchili, Maria Cowen, James Erickson, Pooja Khatkar, Renaud Mahieux, Fatah Kashanchi
Publikováno v:
Cells, Vol 10, Iss 4, p 781 (2021)
Here, we have attempted to address the timing of EV and virion release from virally infected cells. Uninfected (CEM), HIV-1-infected (J1.1), and human T cell leukemia virus-1 (HTLV-1)-infected (HUT102) cells were synchronized in G0. Viral latency was
Externí odkaz:
https://doaj.org/article/9c7c75bd8fcb448aa49f1491dbbd9124
Autor:
Sarah Al Sharif, Daniel O. Pinto, Gifty A. Mensah, Fatemeh Dehbandi, Pooja Khatkar, Yuriy Kim, Heather Branscome, Fatah Kashanchi
Publikováno v:
Viruses, Vol 12, Iss 12, p 1422 (2020)
Human T-cell lymphotropic virus type 1 (HTLV-1) infects 5–10 million people worldwide and is the causative agent of adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) as well as other infla
Externí odkaz:
https://doaj.org/article/b712587021fc4ee3a766e7bf8d2dfecb