Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Heather Boyce"'
Autor:
Saeid Raofi, Minori Kinjo, Dajun Sun, Zhichuan Li, Heather Boyce, Karthika Natarajan, Mitchell Frost, Liang Zhao, Markham Luke, Robert Lionberger, Debra Kelsh, Myong‐Jin Kim
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1977-1987 (2021)
Abstract This study assessed the impact of product particle sizes (fine: 106–500 µm; coarse: 500–1000 µm) on oxycodone pharmacokinetics (PK) following nasal insufflation of milled oxycodone extended‐release (ER) abuse‐deterrent (AD) tablets
Externí odkaz:
https://doaj.org/article/f7d0df0f0a8844c69710608e5b08428c
Publikováno v:
Pharmaceutical Research. 38:1263-1278
A method to reproducibly mill abuse deterrent oxycodone hydrochloride (HCl) extended release (ER) tablets was developed for a nasal insufflation pharmacokinetic (PK) study. Several comminution methods were explored before determining that a conical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0a944fa27271ba07b41436835d23ee
https://doi.org/10.1007/s11095-021-03066-0
https://doi.org/10.1007/s11095-021-03066-0
Autor:
Mitchell Frost, Markham C. Luke, Zhichuan Li, Minori Kinjo, Heather Boyce, Robert Lionberger, Karthika Natarajan, Liang Zhao, Dajun Sun, Myong-Jin Kim, Debra Kelsh, Saeid Raofi
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 5, Pp 1977-1987 (2021)
Clinical and Translational Science, Vol 14, Iss 5, Pp 1977-1987 (2021)
This study assessed the impact of product particle sizes (fine: 106–500 µm; coarse: 500–1000 µm) on oxycodone pharmacokinetics (PK) following nasal insufflation of milled oxycodone extended‐release (ER) abuse‐deterrent (AD) tablets using im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20b3a87bfdbda52f0d87d905d0c4c33
https://pubmed.ncbi.nlm.nih.gov/33982418
https://pubmed.ncbi.nlm.nih.gov/33982418
Autor:
Vadim J. Gurvich, Myke Scoggins, Stephen W. Hoag, Daniel T. Smith, Vivek S Dave, Heather Boyce, Stephen R. Byrn
Publikováno v:
AAPS PharmSciTech. 21
The main goal of the presented work was to understand changes in the microstructure of tablets, as well as the properties of its main component viz. polyethylene oxide (PEO) as a function of sintering. Key polymer variables and sintering conditions w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4441287b540927f210df8cfbc23fc3aa
https://doi.org/10.1208/s12249-019-1594-6
https://doi.org/10.1208/s12249-019-1594-6
Autor:
Bhawana Saluja, Steve Byrn, Vadim J. Gurvich, Stephen W. Hoag, Daniel W. Smith, Heather Boyce, Wen Qu
Publikováno v:
AAPS PharmSciTech. 19:1744-1757
In vitro evaluation of abuse deterrent formulations (ADFs) is a challenge since real abuse situations are variable and ADF technology is evolving. Specifically, an assessment of an ADF to deter nasal insufflation would be valuable. In this study, a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9518079ddaec768f6ffe7895c9ceaf40
https://doi.org/10.1208/s12249-017-0947-2
https://doi.org/10.1208/s12249-017-0947-2
Autor:
Stephen W. Hoag, Michael Popielarczyk, Heather Boyce, Vivek S Dave, Rahul V. Haware, Antoine Al-Achi, Enyioha Ike-Amaechi
Publikováno v:
Journal of Pharmaceutical Sciences. 106:537-545
The predictability of multivariate calibration models, calculated with offline near-infrared spectroscopy (NIRS), assessing impact of magnesium stearate (MgSt) fraction, blending time, and compression force on the tablet breaking force (TBF) of SPRES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeecfd7165ce3522b3fc910a40b69196
https://doi.org/10.1016/j.xphs.2016.09.018
https://doi.org/10.1016/j.xphs.2016.09.018
Autor:
Xin Feng, Dajun Sun, Nahid S. Kamal, Heather Boyce, Celia N. Cruz, Ross Walenga, Ahmed S. Zidan, Xiaoming Xu, Muhammad Ashraf
Publikováno v:
AAPS PharmSciTech. 21(2)
There is a need to develop in vitro dissolution methods that discriminate for particle size of the manipulated abuse deterrent formulation (ADF) and that can be used for in vivo predictive models since dissolution methods developed for intact formula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273c15e22b92cf970b3cb8a78e86aedc
https://pubmed.ncbi.nlm.nih.gov/31897805
https://pubmed.ncbi.nlm.nih.gov/31897805
Autor:
Mary Ann Jabra-Rizk, Amy J. Karlsson, Eric Kong, Stephen W. Hoag, Ahmed Ibrahim, Heather Boyce, Christina Tsui, Timothy F. Meiller
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:881-889
Oral candidiasis (OC), caused by the fungal pathogen Candida albicans , is the most common opportunistic infection in HIV + individuals and other immunocompromised populations. The dramatic increase in resistance to common antifungals has emphasized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba4c463dddd1ab99e1c3fc6b050de6a
https://doi.org/10.1128/aac.02624-15
https://doi.org/10.1128/aac.02624-15
Publikováno v:
Drug development and industrial pharmacy. 44(11)
The monitoring and evaluation of sintering-induced tablet strength of a polyethylene oxide (PEO) based placebo tables was accomplished using infrared spectroscopy (NIRS).Evaluation of high molecular weight PEO-based tablet matrices for abuse deterren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc5c1102ba9e84cf3d40b058e4f4d9b
https://pubmed.ncbi.nlm.nih.gov/30070152
https://pubmed.ncbi.nlm.nih.gov/30070152
