Výsledky vyhledávání - "Heather B. Roesly"

Impact of simulation-based training on perceived provider confidence in acute multidisciplinary pediatric trauma resuscitation

Autor: Inge Morton, Alyssa Rake, Cory McLaughlin, Erica N. Barin, Elizabeth A. Cleek, Heather B. Roesly, Aaron R. Jensen, Rita V. Burke, Randall S. Burd, Minna M. Wieck, Todd P. Chang, Jeffrey S. Upperman, Henri R. Ford, L. Caulette Young, Catherine J. Goodhue

Publikováno v: Pediatric Surgery International. 34:1353-1362

PURPOSE: Simulation-based training has the potential to improve team-based care. We hypothesized that implementation of an in situ multidisciplinary simulation-based training program would improve provider confidence in team-based management of sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c345386880057c7b16bef8341e1e76
https://doi.org/10.1007/s00383-018-4361-y

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Qualitative assessment of simulation-based training for pediatric trauma resuscitation

Autor: Rita V. Burke, Catherine J. Goodhue, L. Caulette Young, Elizabeth A. Cleek, Heather B. Roesly, Aaron R. Jensen, Todd P. Chang, Alyssa Rake, Inge Morton, Natalie E. Demeter, Jeffrey S. Upperman

Publikováno v: Surgery. 161(5)

Background Effective teamwork is critical in the trauma bay, although there is a lack of consensus related to optimal training for these skills. We implemented in situ trauma simulations with debriefing as a possible training methodology to improve t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b131728487ec01a26012a72ca3c92ec4
https://pubmed.ncbi.nlm.nih.gov/27842918

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The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid

Autor: Kimberly A. Hill, Hwu Dau Rw Chen, Katerina Dvorak, Mohammad Rizwan Khan, Heather B. Roesly, George S. Watts, Xiaoxin Chen, Nirushan Narendran

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G864-G872

Beclin-1 has a central role in the regulation of autophagy. Barrett's esophagus (BE) is associated with a significantly increased risk for the development of esophageal adenocarcinoma (EAC). In the current study, we evaluated the role of Beclin-1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103a76471aa498825cb64154de867559
https://doi.org/10.1152/ajpgi.00340.2011

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Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis

Autor: Aaron Goldman, Harris Bernstein, Hwu Dau Rw Chen, Bohuslav Dvorak, Heather B. Roesly, Kimberly A. Hill, Margaret E. Tome, Katerina Dvorak

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 300:G292-G302

Barrett's esophagus (BE) is a premalignant condition, where normal squamous epithelium is replaced by intestinal epithelium. BE is associated with an increased risk of developing esophageal adenocarcinoma (EAC). However, the BE cell of origin is not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05c43d932cbff40afe2275a22d17028
https://doi.org/10.1152/ajpgi.00461.2010

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Su1163 The Loss of Beclin-1 Expression Correlates With Progression to Esophageal Adenocarcinoma and Autophagy Resistance: the Role of Bile Acids

Autor: Hwudaurw Chen, Katerina Dvorak, Heather B. Roesly, Mohammad Rizwan Khan, Nirushan Narendran, Xiaoxin L. Chen

Publikováno v: Gastroenterology. 142:S-441

Background and Aims: Autophagy is a normal physiological mechanism for the degradation of cellular proteins and organelles. Excessive autophagy induced by cellular stress leads to cell death. However, the exact role of autophagy in cancer is not comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f4ef1e7ecf2d4d95ea24fcf97904b40
https://doi.org/10.1016/s0016-5085(12)61658-8

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The Na+/H+ Exchanger Controls Deoxycholic Acid-Induced Apoptosis by a H+-Activated, Na+-Dependent Ionic Shift in Esophageal Cells

Autor: Katerina Dvorak, Aaron Goldman, Kimberly A. Hill, Mohammad Shahidullah, Nicholas A. Delamere, Amritlal Mandal, Hwu Dau Rw Chen, Mohammad R. Khan, Heather B. Roesly

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e23835 (2011)

Apoptosis resistance is a hallmark of cancer cells. Typically, bile acids induce apoptosis. However during gastrointestinal (GI) tumorigenesis the cancer cells develop resistance to bile acid-induced cell death. To understand how bile acids induce ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78147347c30a2fd317c5e7260fb6fa2e
https://doi.org/10.1371/journal.pone.0023835

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Abstract 3793: Bile acids and autophagy resistance in Barrett's esophagus

Autor: Katerina Dvorak, Hwudaurw Chen, Kimberly A. Hill, Heather B. Roesly

Publikováno v: Cancer Research. 71:3793-3793

Background: Barrett's esophagus (BE) is a premalignant lesion of the distal esophagus that is associated with increased risk of esophageal cancer (EAC). Bile acids are implicated in BE development. Autophagy is a tightly-regulated process involving d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9eb7bb4434ddf7a57e3b21c8f527059
https://doi.org/10.1158/1538-7445.am2011-3793

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