Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Heather Ang"'
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(17)
REV-ERB is a member of the nuclear receptor superfamily of transcription factors involved in the regulation of many physiological processes, from circadian rhythm, to immune function and metabolism. Accordingly, REV-ERB has been considered as a promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586bfa15cdbd0a401536b23203f9dea7
https://pubmed.ncbi.nlm.nih.gov/32738989
https://pubmed.ncbi.nlm.nih.gov/32738989
Autor:
Constance Owens-Jasey, Jinying Chen, Ran Xu, Heather Angier, Amy G Huebschmann, Mayuko Ito Fukunaga, Krisda H Chaiyachati, Katharine A Rendle, Kim Robien, Lisa DiMartino, Daniel J Amante, Jamie M Faro, Maura M Kepper, Alex T Ramsey, Eric Bressman, Rachel Gold
Publikováno v:
JMIR Cancer, Vol 10, p e49002 (2024)
BackgroundA substantial percentage of the US population is not up to date on guideline-recommended cancer screenings. Identifying interventions that effectively improve screening rates would enhance the delivery of such screening. Interventions invol
Externí odkaz:
https://doaj.org/article/6651c2519a2e4f87b6d103997e317104
Autor:
Yunda Huang, Lily Zhang, Shelly Karuna, Philip Andrew, Michal Juraska, Joshua A. Weiner, Heather Angier, Evgenii Morgan, Yasmin Azzam, Edith Swann, Srilatha Edupuganti, Nyaradzo M. Mgodi, Margaret E. Ackerman, Deborah Donnell, Lucio Gama, Peter L. Anderson, Richard A. Koup, John Hural, Myron S. Cohen, Lawrence Corey, M. Juliana McElrath, Peter B. Gilbert, Maria P. Lemos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Broadly neutralizing monoclonal antibodies (mAbs) are being developed for HIV-1 prevention. Hence, these mAbs and licensed oral pre-exposure prophylaxis (PrEP) (tenofovir-emtricitabine) can be concomitantly administered in clinical trials. I
Externí odkaz:
https://doaj.org/article/1573cc55a90c4367a36a05f7470f768e
Autor:
Douglas V. Easterling, Rebekah R. Jacob, Ross C. Brownson, Debra Haire-Joshu, Daniel A. Gundersen, Heather Angier, Jennifer E. DeVoe, Sonja Likumahuwa-Ackman, Thuy Vu, Russell E. Glasgow, Robert Schnoll
Publikováno v:
Implementation Science Communications, Vol 4, Iss 1, Pp 1-12 (2023)
Abstract Background Logic models map the short-term and long-term outcomes that are expected to occur with a program, and thus are an essential tool for evaluation. Funding agencies, especially in the United States (US), have encouraged the use of lo
Externí odkaz:
https://doaj.org/article/77a9cd21f6a046bf8cbbcde8342e111a
Autor:
Joshua Martwick, Jorge Kaufmann, Steffani Bailey, Heather Angier, Nathalie Huguet, John Heintzman, Jean O’Malley, Laura Moreno, Jennifer E. DeVoe
Publikováno v:
Journal of Primary Care & Community Health, Vol 15 (2024)
Aims: Children of parents with substance use and/or other mental health (SU/MH) diagnoses are at increased risk for health problems. It is unknown whether these children benefit from receiving primary care at the same clinic as their parents. Thus, a
Externí odkaz:
https://doaj.org/article/69eae46f58e14f6a975d05d784c3db52
Autor:
Kira Eilers, Alexander Lipien, Robert E. Sinden, Berthold Göttgens, Nicola Ruivo, Heather Ang, Andrew M. Blagborough, Ken R. Duffy, Cristina Lo Celso, Myriam L. R. Haltalli, Nicola K. Wilson, Samuel Watcham, Maria L. Vainieri
Severe infections are a major source of stress on haematopoiesis, where consequences for haematopoietic stem cells (HSCs) have only recently started to emerge. HSC function critically depends on the integrity of complex bone marrow niches, which have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8f46f274a98d7e8253541e8d3fe876
https://doi.org/10.1101/477190
https://doi.org/10.1101/477190
Autor:
Delfim, Duarte, Saoirse, Amarteifio, Heather, Ang, Isabella Y, Kong, Nicola, Ruivo, Gunnar, Pruessner, Edwin D, Hawkins, Cristina, Lo Celso
Publikováno v:
Immunology and Cell Biology
The majority of acute myeloid leukemia (AML) patients have a poor response to conventional chemotherapy. The survival of chemoresistant cells is thought to depend on leukemia‐bone marrow (BM) microenvironment interactions, which are not well unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95cdf8c5ea866af11cd219f920984ba6
https://pubmed.ncbi.nlm.nih.gov/30422351
https://pubmed.ncbi.nlm.nih.gov/30422351
Autor:
Bryan T. Mayer, Lily Zhang, Allan C. deCamp, Chenchen Yu, Alicia Sato, Heather Angier, Kelly E. Seaton, Nicole Yates, Julie E. Ledgerwood, Kenneth Mayer, Marina Caskey, Michel Nussenzweig, Kathryn Stephenson, Boris Julg, Dan H. Barouch, Magdalena E. Sobieszczyk, Srilatha Edupuganti, Colleen F. Kelley, M. Juliana McElrath, Huub C. Gelderblom, Michael Pensiero, Adrian McDermott, Lucio Gama, Richard A. Koup, Peter B. Gilbert, Myron S. Cohen, Lawrence Corey, Ollivier Hyrien, Georgia D. Tomaras, Yunda Huang
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 594 (2024)
Monoclonal antibodies are commonly engineered with an introduction of Met428Leu and Asn434Ser, known as the LS mutation, in the fragment crystallizable region to improve pharmacokinetic profiles. The LS mutation delays antibody clearance by enhancing
Externí odkaz:
https://doaj.org/article/34ca5d472d9b40e7a742cd8a83e9c15b
Autor:
Kathryn J. Bonuck, Heather Angier, Sara McCrimmon, Heather Holderness, Jeremy Erroba, Nathalie Huguet, Jennifer E. DeVoe, Patricia A. Carney PhD
Publikováno v:
Journal of Primary Care & Community Health, Vol 14 (2023)
Previous reviews of strategies to increase cervical cancer screening are more than 10 years old, the U.S. continues to fall short of the Healthy People 2030 cervical cancer screening goal, and guidelines were revised in 2018, therefore an updated rev
Externí odkaz:
https://doaj.org/article/d6b93546c90f486dbf1b5fa00ade0ef6
Autor:
Kelly E. Seaton, Yunda Huang, Shelly Karuna, Jack R. Heptinstall, Caroline Brackett, Kelvin Chiong, Lily Zhang, Nicole L. Yates, Mark Sampson, Erika Rudnicki, Michal Juraska, Allan C. deCamp, Paul T. Edlefsen, James I. Mullins, Carolyn Williamson, Raabya Rossenkhan, Elena E. Giorgi, Avi Kenny, Heather Angier, April Randhawa, Joshua A. Weiner, Michelle Rojas, Marcella Sarzotti-Kelsoe, Lu Zhang, Sheetal Sawant, Margaret E. Ackerman, Adrian B. McDermott, John R. Mascola, John Hural, M. Julianna McElrath, Philip Andrew, Jose A. Hidalgo, Jesse Clark, Fatima Laher, Catherine Orrell, Ian Frank, Pedro Gonzales, Srilatha Edupuganti, Nyaradzo Mgodi, Lawrence Corey, Lynn Morris, David Montefiori, Myron S. Cohen, Peter B. Gilbert, Georgia D. Tomaras
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104590- (2023)
Summary: Background: The phase 2b proof-of-concept Antibody Mediated Prevention (AMP) trials showed that VRC01, an anti-HIV-1 broadly neutralising antibody (bnAb), prevented acquisition of HIV-1 sensitive to VRC01. To inform future study design and d
Externí odkaz:
https://doaj.org/article/1fb6811de76c4d6b9e00985ef3384be8