Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.

Autor: Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A McComsey, Dylan McDonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M VanWagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Publikováno v: PLoS ONE, Vol 18, Iss 6, p e0286297 (2023)

ImportanceSARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, tr

Externí odkaz: https://doaj.org/article/c631b9a817d842aa8407fbc8f59463ab

Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19

Autor: Clifford Rostomily, Nathan D. Price, Jeffrey A. Bluestone, Julie A. Wallick, Jessi W Li, Sunga Hong, Rachel Liu, Brett Smith, Chen Dg, Li S, Andrew T. Magis, Rachel Ng, Raphael Gottardo, Leroy Hood, Venkata R Duvvuri, Christopher Lausted, Priyanka Baloni, Lesley Jones, Scott D. Boyd, Naeha Subramanian, Yong Zhou, Phil Greenberg, Ana Jimena Pavlovitch-Bedzyk, Mark M. Davis, Jingyi Xie, William R. Berrington, Chengzhen L. Dai, Heather A. Algren, Fan Yang, Sergey A. Kornilov, Chour W, Rick Edmark, Antoni Ribas, Lewis L. Lanier, Jongchan Choi, Shen Dong, Dan Yuan, Jing Zhou, Zhang R, Christos J. Petropoulos, Kai Wang, Murry K, Pamela Troisch, Kelsey Scherler, Wei Wei, Shannon Fallen, Jennifer Hadlock, Anderson Kg, Lee Rowen, Jason D Goldman, Terri Wrin, Sean Mackay, Yu-Ru Su, Lee I, Heath

The immunological picture of how different patients recover from COVID-19, and how those recovery trajectories are influenced by infection severity, remain unclear. We investigated 140 COVID-19 patients from diagnosis to convalescence using clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63effca7ae7491a4ff238b023965fdef
https://doi.org/10.1101/2021.03.19.21254004

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

Autor: Jing Li, Brett Smith, Andrew T. Magis, Jongchan Choi, Leroy Hood, Sergey A. Kornilov, Guangrong Qin, Venkata R Duvvuri, Valentin Voillet, Kelsey Scherler, Christopher Lausted, Shen Dong, Jennifer Hadlock, Phil Greenberg, Nathan D. Price, D. Shane O’Mahony, Sunga Hong, Yapeng Su, Kim Murray, Yong Zhou, Naeha Subramanian, Heather A. Algren, Rick Edmark, Clifford Rostomily, Alan Aderem, Mark M. Davis, Jeffrey A. Bluestone, Dan Yuan, Jing Zhou, Alexander M. Xu, Ryan Roper, Raphael Gottardo, Cheng Dai, Christopher R. Dale, Lewis L. Lanier, Priyanka Baloni, Kai Wang, Lesley Jones, Jason D Goldman, Julie A. Wallick, Daniel Chen, Sui Huang, Sean Mackay, James R. Heath, Alissa C. Rothchild, Pamela Troisch, Zager A. Michael, Wei Wei

Publikováno v: bioRxiv
bioRxiv, vol 1, iss 08-04

Author(s): Su, Yapeng; Chen, Daniel; Lausted, Christopher; Yuan, Dan; Choi, Jongchan; Dai, Cheng; Voillet, Valentin; Scherler, Kelsey; Troisch, Pamela; Duvvuri, Venkata R; Baloni, Priyanka; Qin, Guangrong; Smith, Brett; Kornilov, Sergey; Rostomily, C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa5c3021b1fddc6886d970132515d06
https://pubmed.ncbi.nlm.nih.gov/32766585

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

Autor: Jenn J. Hadlock, Michael Zager, Rachel Liu, Daniel Chen, Valentin Voillet, Kim Murray, Alan Aderem, Yapeng Su, Jongchan Choi, Philip D. Greenberg, Rongyu Zhang, Yong Zhou, Sui Huang, Alexander M. Xu, Lesley Jones, Raphael Gottardo, Guangrong Qin, Dan Yuan, Chengzhen L. Dai, Jing Zhou, Heather A. Algren, Rick Edmark, Kelsey Scherler, Alissa C. Rothchild, Christopher Lausted, Venkata R Duvvuri, Clifford Rostomily, Naeha Subramanian, Christopher R. Dale, Mark M. Davis, Lewis L. Lanier, Jeffrey A. Bluestone, Jingyi Xie, Sarah Li, Ryan Roper, Jing Li, Brett Smith, Andrew T. Magis, John C. Earls, Sunga Hong, Julie A. Wallick, Sean Mackay, Lee Rowen, Leroy Hood, Priyanka Baloni, Jason D Goldman, Nathan D. Price, James R. Heath, John E. Heath, D. Shane O’Mahony, Sergey A. Kornilov, Shen Dong, Pamela Troisch, Wei Wei, Kai Wang

Publikováno v: Cell

We present an integrated analysis of the clinical measurements, immune cells and plasma multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial blood draws collected during the first week of infection following d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fde863eb21cd1c83cffb975ebafc70
https://doi.org/10.1016/j.cell.2020.10.037

Multiple early factors anticipate post-acute COVID-19 sequelae

Autor: Yapeng Su, Dan Yuan, Daniel G. Chen, Rachel H. Ng, Kai Wang, Jongchan Choi, Sarah Li, Sunga Hong, Rongyu Zhang, Jingyi Xie, Sergey A. Kornilov, Kelsey Scherler, Ana Jimena Pavlovitch-Bedzyk, Shen Dong, Christopher Lausted, Inyoul Lee, Shannon Fallen, Chengzhen L. Dai, Priyanka Baloni, Brett Smith, Venkata R. Duvvuri, Kristin G. Anderson, Jing Li, Fan Yang, Caroline J. Duncombe, Denise J. McCulloch, Clifford Rostomily, Pamela Troisch, Jing Zhou, Sean Mackay, Quinn DeGottardi, Damon H. May, Ruth Taniguchi, Rachel M. Gittelman, Mark Klinger, Thomas M. Snyder, Ryan Roper, Gladys Wojciechowska, Kim Murray, Rick Edmark, Simon Evans, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, William Chour, Heather A. Algren, William R. Berrington, Julie A. Wallick, Rebecca A. Cochran, Mary E. Micikas, Terri Wrin, Christos J. Petropoulos, Hunter R. Cole, Trevan D. Fischer, Wei Wei, Dave S.B. Hoon, Nathan D. Price, Naeha Subramanian, Joshua A. Hill, Jennifer Hadlock, Andrew T. Magis, Antoni Ribas, Lewis L. Lanier, Scott D. Boyd, Jeffrey A. Bluestone, Helen Chu, Leroy Hood, Raphael Gottardo, Philip D. Greenberg, Mark M. Davis, Jason D. Goldman, James R. Heath

Publikováno v: Cell

Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk-factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d279621f37f234b4bc8e46a70c32b5