Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Heather A Minges Wols"'
Autor:
Gregory H, Underhill, Heather A, Minges Wols, Jamie L, Fornek, Pamela L, Witte, Geoffrey S, Kansas, Heather A, Minges-Wols
Publikováno v:
Blood. 99:2905-2912
Long-lived antibody-secreting plasma cells are formed in the secondary lymphoid organs and subsequently home to the bone marrow, although the mechanisms that control this migration remain primarily unknown. In this study, we show that IgG plasma cell
Autor:
Heather A. Minges Wols
Publikováno v:
The Journal of Immunology. 200:113.3-113.3
Columbia College Chicago is a leader in the arts and media. While the Science & Mathematics Department houses a major and 3 minors (including one in biology), the majority of the students matriculating through our courses are fulfilling general educa
Publikováno v:
Journal of Immunological Methods. 329:219-224
Interest in plasma cells has increased greatly in the past decade. While several studies have examined the longevity and transcriptional control of antibody secreting cells in vivo, few studies have examined freshly isolated plasma cells ex vivo. Stu
Publikováno v:
The Journal of Immunology. 198:215.8-215.8
The ability of long-lived plasma cells (LLPC) to maintain longevity and avoid metabolic burnout has been largely unexplored until recently. Our lab has shown that LLPC reside in hypoxic niches and are divided into two distinct subsets based on fluore
Publikováno v:
The Journal of Immunology. 196:204.27-204.27
The metabolic stress of being an antibody-secreting cell is likely great. Indeed, existing literature suggests short-lived plasma cells (SLPC) die due to high metabolic stress. How long-lived (LL) PC maintain longevity and escape the same fate as SLP
Autor:
Zheng Yu, Pamela L. Witte, Jessica L. Palmer, Fletcher A. White, Jill A. Ippolito, Heather A. Minges Wols, Phong T. Le
Publikováno v:
International immunology. 19(7)
Two populations of plasma cells (PCs) are formed after immunization. A short-lived population in the spleen and lymph nodes provides rapid protection. A long-lived population, mainly in the bone marrow, provides lasting immunity. The mechanisms respo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(8)
Protective circulating Abs originate primarily from long-lived plasma cells in the bone marrow. However, the molecular and cellular basis of plasma cell longevity is unknown. We investigated the capacity of primary bone marrow-derived stromal cells t
Autor:
Heather A. Minges Wols, Jill A. Ippolito, Zheng Yu, Jessica L. Palmer, Fletcher A. White, Phong T. Le, Pamela L. Witte
Publikováno v:
International Immunology; Jul2007, Vol. 19 Issue 7, p837-837, 1p