Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Heather A Harrington"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009094 (2021)
Angiogenesis is the process by which blood vessels form from pre-existing vessels. It plays a key role in many biological processes, including embryonic development and wound healing, and contributes to many diseases including cancer and rheumatoid a
Externí odkaz:
https://doaj.org/article/24875cb0b6f143c9b9e5b1a630a64832
Publikováno v:
EPJ Data Science, Vol 6, Iss 1, Pp 1-38 (2017)
Abstract Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates, a
Externí odkaz:
https://doaj.org/article/3930a2447980439dab1cad994f28acdb
Autor:
Sophie K Kay, Heather A Harrington, Sarah Shepherd, Keith Brennan, Trevor Dale, James M Osborne, David J Gavaghan, Helen M Byrne
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 2, p e1005400 (2017)
The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate specification is coordinated via Notch's interaction with the canonical Wnt pathway. Here, we propo
Externí odkaz:
https://doaj.org/article/1b7e3c6312aa4bb1b524780846a7cee7
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19895 (2011)
Atopic dermatitis (AD) is a widely spread cutaneous chronic disease characterised by sensitive reactions (eg. eczema) to normally innocuous elements. Although relatively little is understood about its underlying mechanisms due to its complexity, skin
Externí odkaz:
https://doaj.org/article/e94c417881694e44988eaa1e72a8c13c
Autor:
Kenneth L Ho, Heather A Harrington
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 10, p e1000956 (2010)
Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas which, on binding to its cognate ligand FasL, oligomerize to form the death-
Externí odkaz:
https://doaj.org/article/ba7de3baee4240679cb37d31218d2aa2
Publikováno v:
Physical Review Research, Vol 5, Iss 4, p 043006 (2023)
This paper is part of the Physical Review Research collection titled Physics of Neuroscience. The geometry of neurons is known to be important for their functions. Hence, neurons are often classified by their morphology. Two recent methods, persisten
Externí odkaz:
https://doaj.org/article/ee7ce11a733f463594edc8d568ecf651
Autor:
Renee S. Hoekzema, Lewis Marsh, Otto Sumray, Thomas M. Carroll, Xin Lu, Helen M. Byrne, Heather A. Harrington
Publikováno v:
Hoekzema, R S, Marsh, L, Sumray, O, Carroll, T M, Lu, X, Byrne, H M & Harrington, H A 2022, ' Multiscale Methods for Signal Selection in Single-Cell Data ', Entropy, vol. 24, no. 8, 1116, pp. 1-29 . https://doi.org/10.3390/e24081116
Entropy; Volume 24; Issue 8; Pages: 1116
Entropy, 24(8):1116, 1-29. Multidisciplinary Digital Publishing Institute (MDPI)
Entropy; Volume 24; Issue 8; Pages: 1116
Entropy, 24(8):1116, 1-29. Multidisciplinary Digital Publishing Institute (MDPI)
Analysis of single-cell transcriptomics often relies on clustering cells and then performing differential gene expression (DGE) to identify genes that vary between these clusters. These discrete analyses successfully determine cell types and markers;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e009243f0fe0ec29ffad6212aa737faf
https://research.vu.nl/en/publications/4657ad1b-d1b4-42d2-be73-f88fd85ba023
https://research.vu.nl/en/publications/4657ad1b-d1b4-42d2-be73-f88fd85ba023
Autor:
Bernadette J. Stolz, Jakob Kaeppler, Bostjan Markelc, Franziska Braun, Florian Lipsmeier, Ruth J. Muschel, Helen M. Byrne, Heather A. Harrington
Publikováno v:
Science advances. 8(23)
Advances in imaging techniques enable high-resolution three-dimensional (3D) visualization of vascular networks over time and reveal abnormal structural features such as twists and loops, and their quantification is an active area of research. Here,
Autor:
Paolo Tripoli, Jonathan D. Hauenstein, Emilie Dufresne, Heather A. Harrington, Panayotis G. Kevrekidis
Our aim in the present work is to identify all the possible standing wave configurations involving few vortices of different charges in an atomic Bose-Einstein condensate (BEC). In this effort, we deploy the use of a computational algebra approach in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf34d19e703c83330f731a1555696072
https://doi.org/10.1016/j.aam.2020.102099
https://doi.org/10.1016/j.aam.2020.102099
Autor:
Katherine Benjamin, Lamisah Mukta, Gabriel Moryoussef, Christopher Uren, Heather A. Harrington, Ulrike Tillmann, Agnese Barbensi
Quantification and classification of protein structures, such as knotted proteins, often requires noise-free and complete data. Here we develop a mathematical pipeline that systematically analyzes protein structures. We showcase this geometric framew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdd9fcede80e5d84f762555d197d889