Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Heather, Sheardown"'
Autor:
Kyle Battiston, Ian Parrag, Matthew Statham, Dimitra Louka, Hans Fischer, Gillian Mackey, Adam Daley, Fan Gu, Emily Baldwin, Bingqing Yang, Ben Muirhead, Emily Anne Hicks, Heather Sheardown, Leonid Kalachev, Christopher Crean, Jeffrey Edelman, J. Paul Santerre, Wendy Naimark
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Polymer-based systems are often considered a necessity for controlled drug delivery, but have well-known limitations. Here, the authors report on drug delivery implants formed solely from corticosteroid dimers, which demonstrate controlled release an
Externí odkaz:
https://doaj.org/article/bef9dd810b064602859deb552da70df7
Autor:
Scott D. Fitzpatrick, Mohammad Abu Jafar Mazumder, Lindsay E. Fitzpatrick, Ben Muirhead, Shelley R. Boyd, Talena Rambarran, Heather Sheardown
Publikováno v:
Canadian Journal of Chemistry. 101:59-69
Restrictive barriers and efficient clearance mechanisms make delivery of therapeutics to the back of the eye particularly challenging. An optically transparent, thermally gelling copolymer scaffold that can simply be mixed with an active pharmaceutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::313189582d1b20bdfa2601bab5ea90d9
https://doi.org/10.1139/cjc-2022-0187
https://doi.org/10.1139/cjc-2022-0187
Autor:
Lyndon Jones, Nathan Efron, Kalika Bandamwar, Melissa Barnett, Deborah S. Jacobs, Isabelle Jalbert, Heiko Pult, Michelle K. Rhee, Heather Sheardown, Joseph P. Shovlin, Ulli Stahl, Adriana Stanila, Jacqueline Tan, Silvia Tavazzi, Omur O. Ucakhan, Mark D.P. Willcox, Laura E. Downie
Publikováno v:
The Ocular Surface.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeced6b7937b28c5692cc3a39e9c38eb
https://doi.org/10.1016/j.jtos.2023.04.010
https://doi.org/10.1016/j.jtos.2023.04.010
Publikováno v:
Bioconjugate Chemistry. 33:634-642
Radiolabeling a protein, molecule, or polymer can provide accurate and precise quantification in biochemistry, biomaterials, pharmacology, and drug delivery research. Herein, we describe a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49675f67657f76395754b03cbf6f5cc7
https://doi.org/10.1021/acs.bioconjchem.2c00047
https://doi.org/10.1021/acs.bioconjchem.2c00047
Publikováno v:
Acta Biomaterialia. 141:151-163
Thermo-gels based on chitosan crosslinked poly(N-isopropylacrylamide) were developed as alternatives to conventional eye drops for the sustained release of ketotifen fumarate in the treatment of allergic conjunctivitis. The thermo-gelling properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d975488dbf2eb24dfdc389f9abbbe791
https://doi.org/10.1016/j.actbio.2022.01.043
https://doi.org/10.1016/j.actbio.2022.01.043
Autor:
Mitchell Ross, Heather Sheardown
Publikováno v:
Advanced Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b89b6b0f04f1db224acc4a18da66809f
https://doi.org/10.1002/adtp.202300068
https://doi.org/10.1002/adtp.202300068
Autor:
Mitchell Ross, Lindsay Sheardown, Benjamin Muirhead, Jonathan Mofford, Jennifer (JingYuan) Tian, Heather Sheardown
Publikováno v:
Journal of Biomedical Materials Research Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d131a2400b014de67ac66bfb40849fd3
https://doi.org/10.1002/jbm.a.37541
https://doi.org/10.1002/jbm.a.37541
Publikováno v:
Nanomaterials, Vol 10, Iss 7, p 1400 (2020)
While the use of topical drops for the delivery of drugs to the anterior of the eye is well accepted, it is far from efficient with as little as 5% of the drug instilled on the eye actually reaching the target tissue. The ability to prolong the resid
Externí odkaz:
https://doaj.org/article/0be2577e932946479f38d6132b4c290f
Autor:
Todd Hoare, Maya Ziolkowska, Taylor C. Goostrey, Heather Sheardown, Ridhdhi S. Dave, Sofia Czerny-Holownia
Publikováno v:
Journal of Controlled Release. 336:71-88
There is a growing demand for effective treatments for ocular conditions that improve patient compliance and reduce side-effects. While methods such as implants and injections have proven effective, topical administration remains the method of choice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1b3a2f1621e7daecf24b7060818804
https://doi.org/10.1016/j.jconrel.2021.06.011
https://doi.org/10.1016/j.jconrel.2021.06.011