Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heathcote, Helen R."'
Autor:
Wilson, Calum, Zhang, Xun, Lee, Matthew D., MacDonald, Margaret, Heathcote, Helen R., Alorfi, Nasser M.N., Buckley, Charlotte, Dolan, Sharron, McCarron, John G.
Publikováno v:
In Metabolism October 2020 111
Autor:
McCarron, John G, Wilson, Calum, Heathcote, Helen R, Zhang, Xun, Buckley, Charlotte, Lee, Matthew D
Publikováno v:
In Current Opinion in Pharmacology April 2019 45:23-32
Autor:
Wilson, Calum, Lee, Matthew D., Heathcote, Helen R., Zhang, Xun, Buckley, Charlotte, Girkin, John M., Saunter, Christopher D., McCarron, John G.
Publikováno v:
In Journal of Biological Chemistry 18 January 2019 294(3):737-758
Autor:
Heathcote, Helen R.1 (AUTHOR), Lee, Matthew D.1 (AUTHOR), Zhang, Xun1 (AUTHOR), Saunter, Christopher D.2 (AUTHOR), Wilson, Calum1 (AUTHOR), McCarron, John G.1 (AUTHOR) john.mccarron@strath.ac.uk
Publikováno v:
British Journal of Pharmacology. Sep2019, Vol. 176 Issue 17, p3297-3317. 21p. 1 Diagram, 10 Graphs.
Increased vascular contractility in hypertension results from impaired endothelial calcium signaling
Autor:
Wilson, Calum, Zhang, Xun, Buckley, Charlotte, Heathcote, Helen R., Lee, Matthew D., McCarron, John G.
Endothelial cells line all blood vessels and are critical regulators of vascular tone. In hypertension, disruption of endothelial function alters the release of endothelial-derived vasoactive factors and results in increased vascular tone. Although t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::a85518bd0fb8e4d7d27997cee5a7d546
https://strathprints.strath.ac.uk/69951/1/Wilson_etal_Hypertension_2019_Increased_vascular_contractility_in_hypertension_results_from_impaired_endothelial_calcium_signaling.pdf
https://strathprints.strath.ac.uk/69951/1/Wilson_etal_Hypertension_2019_Increased_vascular_contractility_in_hypertension_results_from_impaired_endothelial_calcium_signaling.pdf
Autor:
Heathcote, Helen R., Lee, Matthew D., Zhang, Xun, Saunter, Christopher D., Wilson, Calum, McCarron, John G.
Publikováno v:
British journal of Pharmacology, 2019, Vol.176(17), pp.3297-3317 [Peer Reviewed Journal]
British Journal of Pharmacology
British Journal of Pharmacology
Background and Purpose: The TRPV4 ion channels are Ca 2+ permeable, non-selective cation channels that mediate large, but highly localized, Ca 2+ signals in the endothelium. The mechanisms that permit highly localized Ca 2+ changes to evoke cell-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b01314b607aaee9f973d783773cadb24
http://dro.dur.ac.uk/28845/
http://dro.dur.ac.uk/28845/
Autor:
Wilson, Calum, Lee, Matthew D., Heathcote, Helen R., Zhang, Xun, Buckley, Charlotte, Girkin, John M., Saunter, Christopher D., McCarron, John G.
Endothelial cells are reported to be glycolytic and to minimally rely on mitochondria for ATP generation. Rather than providing energy, mitochondria in endothelial cells may act as signaling organelles that control cytosolic Ca2+ signaling or modify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::83420ff3345a5134e5bdb91b5f02975d
https://strathprints.strath.ac.uk/66287/8/Wilson_etal_JBC_2018_Mitochondrial_ATP_production_provides_long_range_control_of_endothelial.pdf
https://strathprints.strath.ac.uk/66287/8/Wilson_etal_JBC_2018_Mitochondrial_ATP_production_provides_long_range_control_of_endothelial.pdf
Autor:
Heathcote, Helen R., Mancini, Sarah J., Strembitska, Anastasiya, Jamal, Kunzah, Reihill, James A., Palmer, Timothy M., Gould, Gwyn W., Salt, Ian P.
Publikováno v:
Heathcote, H R, Mancini, S J, Strembitska, A, Jamal, K, Reihill, J A, Palmer, T M, Gould, G W & Salt, I P 2016, ' Protein Kinase C phosphorylates AMP-activated protein kinase α1 Ser487 ', Biochemical Journal . https://doi.org/10.1042/BCJ20160211
Biochemical Journal
Biochemical Journal
The key metabolic regulator, AMP-activated protein kinase (AMPK), is reported to be down-regulated in metabolic disorders, but the mechanisms are poorly characterised. Recent studies have identified phosphorylation of the AMPKα1/α2 catalytic subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b30d490268a4c4efbdbb76ee4a6bb73
https://strathprints.strath.ac.uk/70181/1/Heathcote_etal_BJ2016_Protein_kinase_C_phosphorylates_AMP_activated_protein_kinase_1_Ser487.pdf
https://strathprints.strath.ac.uk/70181/1/Heathcote_etal_BJ2016_Protein_kinase_C_phosphorylates_AMP_activated_protein_kinase_1_Ser487.pdf
Autor:
Wilson C; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Zhang X; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Buckley C; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Heathcote HR; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Lee MD; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., McCarron JG; From the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2019 Nov; Vol. 74 (5), pp. 1200-1214. Date of Electronic Publication: 2019 Sep 23.
Autor:
Heathcote HR; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK., Lee MD; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK., Zhang X; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK., Saunter CD; Centre for Advanced Instrumentation, Biophysical Sciences Institute, Department of Physics, Durham University, Durham, UK., Wilson C; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK., McCarron JG; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, UK.
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (17), pp. 3297-3317. Date of Electronic Publication: 2019 Jul 24.