Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Heath L Bradley"'
Autor:
Jonathan Metts, Heath L. Bradley, Zhengqi Wang, Neil P. Shah, Reuben Kapur, Jack L. Arbiser, Kevin D. Bunting
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML). Inhibitors to FLT3 have already been tested in clinical trials, howev
Externí odkaz:
https://doaj.org/article/194b5d0b84eb4fd8aa2867b88dfc9dc5
Autor:
Zhengqi Wang, Tian Mi, Heath L. Bradley, Jonathan Metts, Himalee Sabnis, Wandi Zhu, Jack Arbiser, Kevin D. Bunting
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 956 (2021)
Acute myeloid leukemia (AML) is a heterogeneous disease with a high relapse rate. Cytokine receptor targeted therapies are therapeutically attractive but are subject to resistance-conferring mutations. Likewise, targeting downstream signaling pathway
Externí odkaz:
https://doaj.org/article/55cef3b857214f6c9597debf32e669f4
Autor:
Ahmed Babiker, Michael A Martin, Charles Marvil, Stephanie Bellman, Robert A Petit III, Heath L Bradley, Victoria D Stittleburg, Jessica Ingersoll, Colleen S Kraft, Yan Li, Jing Zhang, Clinton R Paden, Timothy D Read, Jesse J Waggoner, Katia Koelle, Anne Piantadosi
Publikováno v:
Virus evolution. 8(1)
In early 2020, as diagnostic and surveillance responses for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ramped up, attention focused primarily on returning international travelers. Here, we build on existing studies characterizing ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a594f634e39b2b493ae5590eb586fbdc
https://pubmed.ncbi.nlm.nih.gov/35317348
https://pubmed.ncbi.nlm.nih.gov/35317348
Autor:
Ann Chahroudi, Anne Piantadosi, Jessica Ingersoll, Greg S. Martin, Heath L. Bradley, Samuel D. Stampfer, Jesse J. Waggoner, Raymond F. Schinazi, Leda Bassit, Max Su, Wilbur A. Lam, Victoria Stittleburg, Maud Mavigner, Nils Schoof, Ahmed Babiker, Anuradha Rao, Katherine Immergluck, Colleen S. Kraft, Vi Nguyen
Publikováno v:
Journal of Clinical Microbiology
To provide an accessible and inexpensive method to surveil for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations, we developed a multiplex real-time reverse transcription-PCR (rRT-PCR) assay, the Spike single-nucleotide polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53fdeac64a0baf1bbbd9195ce57ef4e
https://doi.org/10.1128/jcm.01446-21
https://doi.org/10.1128/jcm.01446-21
Autor:
Colleen S. Kraft, Anne Piantadosi, Victoria Stittleburg, Jessica Ingersoll, Michael A. Martin, Robert A. Petit, Heath L. Bradley, Katia Koelle, Timothy D. Read, Stephanie Bellman, Charles E. Marvil, Jesse J. Waggoner, Ahmed Babiker
In early 2020, as SARS-CoV-2 diagnostic and surveillance responses ramped up, attention focused primarily on returning international travelers. Here, we build on existing studies characterizing early patterns of SARS-CoV-2 spread within the U.S. by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52d2a26a02612587cb815bbfb5bb9272
https://doi.org/10.1101/2021.09.19.21262615
https://doi.org/10.1101/2021.09.19.21262615
Autor:
Himalee S. Sabnis, Tian Mi, Wandi Zhu, Heath L. Bradley, Jonathan L. Metts, Zhengqi Wang, Kevin D. Bunting, Jack L. Arbiser
Publikováno v:
Antioxidants
Volume 10
Issue 6
Antioxidants, Vol 10, Iss 956, p 956 (2021)
Volume 10
Issue 6
Antioxidants, Vol 10, Iss 956, p 956 (2021)
Acute myeloid leukemia (AML) is a heterogeneous disease with a high relapse rate. Cytokine receptor targeted therapies are therapeutically attractive but are subject to resistance-conferring mutations. Likewise, targeting downstream signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d028237db65cee9a2fe226522018d3
https://pubmed.ncbi.nlm.nih.gov/34203664
https://pubmed.ncbi.nlm.nih.gov/34203664
Autor:
Autum Key, Heath L. Bradley, Anne Piantadosi, Ahmed Babiker, Jesse J. Waggoner, Victoria Stittleburg, Colleen S. Kraft
Publikováno v:
Open Forum Infectious Diseases
Background Broad testing for respiratory viruses among persons under investigation (PUI) for SARS-CoV-2 is performed inconsistently, limiting our understanding of alternative infections and co-infections in these patients. Here, we used unbiased meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50bcdeb69ba7e964efceae2237b7842
http://europepmc.org/articles/PMC7778260
http://europepmc.org/articles/PMC7778260
Autor:
Wen Mei Yu, Kevin D. Bunting, William Tse, Shweta Tripathi, Himalee S. Sabnis, Cheng-Kui Qu, Heath L. Bradley
Publikováno v:
Leukemia Research. 50:132-140
Current therapy for acute myeloid leukemia (AML) primarily includes high-dose cytotoxic chemotherapy with or without allogeneic stem cell transplantation. Targeting unique cellular metabolism of cancer cells is a potentially less toxic approach. Mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e846067c3a2c8df5c099e2e4361b0b10
https://doi.org/10.1016/j.leukres.2016.10.004
https://doi.org/10.1016/j.leukres.2016.10.004
Autor:
Reuben Kapur, Jack L. Arbiser, Neil P. Shah, Jonathan L. Metts, Zhengqi Wang, Kevin D. Bunting, Heath L. Bradley
Publikováno v:
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML). Inhibitors to FLT3 have already been tested in clinical trials, however, drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50373363b390e1cfe0c3c189aa572bda
https://escholarship.org/uc/item/3j87x6gk
https://escholarship.org/uc/item/3j87x6gk
Autor:
Robert G. Hawley, William G. Stetler-Stevenson, Carisa Lahoda, Maryalice Stetler-Stevenson, Heath L. Bradley, Teresa S. Hawley, Peter Haviernik, Ali Ramezani, Kevin D. Bunting
Publikováno v:
Oncogene. 23:9212-9219
The balance between matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) is important for extracellular matrix interactions of hematopoietic cells. MMP-independent growth modulating activity for TIMP-1 on B lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c402efa35ed90bef76a03f7f56dcb2
https://doi.org/10.1038/sj.onc.1208096
https://doi.org/10.1038/sj.onc.1208096