Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis

Autor: Tom W J Huizinga, Hans Scheffer, Piet L. C. M. van Riel, T.L.Th.A. Jansen, Anne Barton, Henk-Jan Guchelaar, Paul P. Tak, Ellen A J Dutmer, Leonid Padyukov, Remco R. R. Makkinje, Han G. Brunner, Sita H. Vermeulen, Peter K. Gregersen, Robert M. Plenge, Xavier Mariette, Timothy R D J Radstake, Renee Allaart, Corinne Miceli, Dirk Jan Van Schaardenburg, Pilar Barrera, Maša Umićević Mirkov, S. Louis Bridges, Marieke J H Coenen, Niek de Vries, Annette Lee, Jing Cui, Barbara Franke, Mart A F J van de Laar, Eli A. Stahl, Saedis Saevarsdottir, Erik J M Toonen, Lindsey A. Criswell

Publikováno v: Annals of the Rheumatic Diseases, 72, 8, pp. 1375-81
Annals of the Rheumatic Diseases, 72, 1375-81
Annals of the rheumatic diseases, vol 72, iss 8
Annals of the rheumatic diseases, 72, 1375-1381. BMJ
Annals of the rheumatic diseases, 72(8), 1375-1381. BMJ Publishing Group
Annals of the Rheumatic Diseases, 72(8), 1375-1381. BMJ Publishing Group
Mirkov, M U, Cui, J, Vermeulen, S H, Stahl, E A, Toonen, E J M, Makkinje, R R, Lee, A T, Huizinga, T W J, Allaart, R, Barton, A, Mariette, X, Miceli, C R, Criswell, L A, Tak, P P, de Vries, N, Saevarsdottir, S, Padyukov, L, Bridges, S L, van Schaardenburg, D, Jansen, T L, Dutmer, E A J, van de Laar, M A F J, Barrera, P, Radstake, T R D J, van Riel, P L C M, Scheffer, H, Franke, B, Brunner, H G, Plenge, R M, Gregersen, P K, Guchelaar, H J & Coenen, M J H 2013, ' Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis ', Annals of the Rheumatic Diseases, vol. 72, no. 8, pp. 1375-1381 . https://doi.org/10.1136/annrheumdis-2012-202405
Annals of the Rheumatic Diseases, 72(8), 1375-1381

Contains fulltext : 118482.pdf (Publisher’s version ) (Open Access) BACKGROUND: Treatment strategies blocking tumour necrosis factor (anti-TNF) have proven very successful in patients with rheumatoid arthritis (RA). However, a significant subset of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1200625a9d12ca0938a6cd05b0c87504
https://doi.org/10.1136/annrheumdis-2012-202405

Neutrophil-mediated inhibition of proinflammatory cytokine responses

Autor: Jos W. M. van der Meer, Mihai G. Netea, Frank L. van de Veerdonk, Mark S. Gresnigt, Charles A. Dinarello, Leo A. B. Joosten, Ineke Verschueren

Publikováno v: Journal of Immunology, 189, 4806-15
Journal of Immunology, 189, 10, pp. 4806-15

Neutrophils (polymorphonuclear neutrophils [PMNs]) play an elaborate role in the innate immune response against invading pathogens. Recent research provided evidence that PMNs can play a modulatory role in inflammation next to their primary role of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadd44dab2db28cc5b52628423e5be54
https://hdl.handle.net/2066/108827

Pomegranate seed oil, a rich source of punicic acid, prevents diet-induced obesity and insulin resistance in mice

Autor: Raquel Hontecillas, Louis M. Havekes, Peter J. Voshol, Irene O.C.M. Vroegrijk, Luisa Gambelli, Gerben Zondag, Janna A. van Diepen, Sjoerd A.A. van den Berg, Johannes A. Romijn, Josep Bassaganya-Riera, Hiskias G. Keizer, Irene Westbroek

Publikováno v: Food and Chemical Toxicology, 49, 1426-30
Food and Chemical Toxicology, 49, 6, pp. 1426-30
Food and chemical toxicology, 49(6), 1426-1430. Elsevier Limited
Food and Chemical Toxicology; Vol 49
Food and Chemical Toxicology

Item does not contain fulltext BACKGROUND: Pomegranate seed oil has been shown to protect against diet induced obesity and insulin resistance. OBJECTIVE: To characterize the metabolic effects of punicic acid on high fat diet induced obesity and insul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b466869fe4fd83dd4e11202d153052
https://doi.org/10.1016/j.fct.2011.03.037

Protection from RNA and DNA viruses by IL-32

Autor: Jarod A. Zepp, Charles A. Dinarello, Marcel F. Nold, Claudia A. Nold-Petry

Publikováno v: Journal of Immunology, 186, 7, pp. 4110-8
Journal of Immunology, 186, 4110-8

Several studies have documented a proinflammatory role for IL-32, which induces IL-1α, IL-1β, IL-6, TNF, and chemokines via NF-κB, p38MAPK, and AP-1. However, IL-32 also participates in the responses to infection with viruses such as HIV-1 and inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9935321e8d1f2b4fb17b01244a405f8b
https://hdl.handle.net/2066/98260

Candida albicans Primes TLR Cytokine Responses through a Dectin-1/Raf-1–Mediated Pathway

Autor: Bart Jan Kullberg, Jessica Quintin, Daniela C. Ifrim, Trees Jansen, Leo A. B. Joosten, Neil A. R. Gow, Liesbeth Jacobs, Mihai G. Netea, David L. Williams, Jos W. M. van der Meer

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, 190 (8), pp.4129-4135. ⟨10.4049/jimmunol.1202611⟩
Journal of Immunology, 190, 8, pp. 4129-35
The Journal of Immunology
Journal of Immunology, 190, 4129-35

The immune system is essential to maintain homeostasis with resident microbial populations, ensuring that the symbiotic host–microbial relationship is maintained. In parallel, commensal microbes significantly shape mammalian immunity at the host mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb635967451f4ee7298de67756d25d0
https://europepmc.org/articles/PMC3619528/