COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation.

Autor: Aboudounya, Mohamed M.¹ (AUTHOR), Heads, Richard J.¹ (AUTHOR)

Publikováno v: Mediators of Inflammation. 1/15/2021, p1-18. 18p.

Cardiac Expression of Brn-3a and Brn-3b POU Transcription Factors and Regulation of Hsp27 Gene Expression

Autor: Farooqui-Kabir, Saleha R., Diss, James K. J., Henderson, Deborah, Marber, Michael S., Latchman, David S., Budhram-Mahadeo, Vishwanie, Heads, Richard J.

Publikováno v: Cell Stress & Chaperones, 2008 Sep 01. 13(3), 297-312.

Externí odkaz: https://www.jstor.org/stable/20456325

Loss of protein kinase novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation and exacerbated ischaemia-reperfusion injury

Autor: Francois, Asvi A, Obasanjo-Blackshire, Kofo, Clark, James E, Boguslavskyi, Andrii, Holt, Mark R, Parker, Peter J, Marber, Michael S, Heads, Richard J

Publikováno v: Francois, A A, Obasanjo-Blackshire, K, Clark, J E, Boguslavskyi, A, Holt, M R, Parker, P J, Marber, M S & Heads, R J 2017, ' Loss of protein kinase novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation and exacerbated ischaemia-reperfusion injury ', Cardiovascular Research . https://doi.org/10.1093/cvr/cvx206

AimsPKN1 is a stress-responsive protein kinase acting downstream of small GTP-binding proteins of the Rho/Rac family. The aim was to determine its role in endogenous cardioprotection.Methods and resultsHearts from PKN1 knockout (KO) or wild type (WT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::a2579b7af60246b55b10eea1dbba14c7
https://kclpure.kcl.ac.uk/en/publications/86d2cc25-2dd2-4dc2-af50-8dbcfb438ae2

Signalling mechanisms in the cardiovascular protective effects of estrogen: With a focus on rapid/membrane signalling.

Autor: Niță, Ana-Roberta, Knock, Greg A., Heads, Richard J.

Publikováno v: Current Research in Physiology; January 2021, Vol. 4 Issue: 1 p103-118, 16p

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