Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Head, M. S."'
Autor:
Daines, R. A., Pendrak, I., Sham, K., Van Aller, G. S., Konstantinidis, A. K., Lonsdale, J. T., Janson, C. A., Qiu, X., Brandt, M., Khandekar, S. S., Silverman, C., Head, M. S.
The first cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor is reported. The inhibitor was obtained by rational modification of a high throughput screening lead with the aid of a S. pneumoniae FabH homology mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::010e214a0bd05457a9684d0bc58a3699
http://olympias.lib.uoi.gr/jspui/handle/123456789/21552
http://olympias.lib.uoi.gr/jspui/handle/123456789/21552
Autor:
Marquis, R. W., James, I., Zeng, J., Trout, R. E. L., Thompson, S., Rahman, A., Yamashita, D. S., Xie, R., Ru, Y., Gress, C. J., Blake, S., Lark, M. A., Hwang, S.-M., Tomaszek, T., Offen, P., Head, M. S., Cummings, M. D., Veber, D. F.
Publikováno v:
Journal of Medicinal Chemistry; November 2005, Vol. 48 Issue: 22 p6870-6878, 9p
Autor:
Seefeld, M. A., Miller, W. H., Newlander, K. A., Burgess, W. J., DeWolf, W. E., Jr., Elkins, P. A., Head, M. S., Jakas, D. R., Janson, C. A., Keller, P. M., Manley, P. J., Moore, T. D., Payne, D. J., Pearson, S., Polizzi, B. J., Qiu, X., Rittenhouse, S. F., Uzinskas, I. N., Wallis, N. G., Huffman, W. F.
Publikováno v:
Journal of Medicinal Chemistry; April 2003, Vol. 46 Issue: 9 p1627-1635, 9p
Autor:
Miller, W. H., Seefeld, M. A., Newlander, K. A., Uzinskas, I. N., Burgess, W. J., Heerding, D. A., Yuan, C. C. K., Head, M. S., Payne, D. J., Rittenhouse, S. F., Moore, T. D., Pearson, S. C., Berry, V., DeWolf, W. E., Jr., Keller, P. M., Polizzi, B. J., Qiu, X., Janson, C. A., Huffman, W. F.
Publikováno v:
Journal of Medicinal Chemistry; July 2002, Vol. 45 Issue: 15 p3246-3256, 11p
Autor:
Lee, D, Long, S A, Adams, J L, Chan, G, Vaidya, K S, Francis, T A, Kikly, K, Winkler, J D, Sung, C M, Debouck, C, Richardson, S, Levy, M A, DeWolf, W E, Keller, P M, Tomaszek, T, Head, M S, Ryan, M D, Haltiwanger, R C, Liang, P H, Janson, C A, McDevitt, P J, Johanson, K, Concha, N O, Chan, W, Abdel-Meguid, S S, Badger, A M, Lark, M W, Nadeau, D P, Suva, L J, Gowen, M, Nuttall, M E
Publikováno v:
Journal of Biological Chemistry; May 2000, Vol. 275 Issue: 21 p16007-14, 8p
Publikováno v:
The Journal of Physical Chemistry - Part B; February 11, 1999, Vol. 103 Issue: 6 p1031-1044, 14p
Autor:
Marquis, R. W., Yamashita, D. S., Ru, Y., LoCastro, S. M., Oh, H.-J., Erhard, K. F., DesJarlais, R. L., Head, M. S., Smith, W. W., Zhao, B., Janson, C. A., Abdel-Meguid, S. S., Tomaszek, T. A., Levy, M. A., Veber, D. F.
Publikováno v:
Journal of Medicinal Chemistry; September 10, 1998, Vol. 41 Issue: 19 p3563-3567, 5p
Publikováno v:
The Journal of Physical Chemistry - Part A; February 20, 1997, Vol. 101 Issue: 8 p1609-1618, 10p
Autor:
Head MS; Physical and Structural Chemistry, SmithKline Beecham Pharmaceuticals, King of Prussia, PA 19406, USA. Martha_S_Head@sbphrd.com, Ryan MD, Lee D, Feng Y, Janson CA, Concha NO, Keller PM, deWolf WE Jr
Publikováno v:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2001 Dec; Vol. 15 (12), pp. 1105-17.