A genetically encoded tool to increase cellular NADH/NAD ⁺ ratio in living cells.

Autor: Pan X; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA., Heacock ML; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA.; Calibr, The Scripps Research Institute, La Jolla, CA, USA., Abdulaziz EN; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA.; Process Development Associate, Amgen, Thousand Oaks, CA, USA., Violante S; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zuckerman AL; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA.; Program in Mathematics and Science Education, University of California San Diego, San Diego, CA, USA.; Program in Mathematics and Science Education, San Diego State University, San Diego, USA., Shrestha N; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA., Yao C; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA., Goodman RP; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cracan V; Laboratory of Redox Biology and Metabolism, Scintillon Institute, San Diego, CA, USA. vcracan@scripps.edu.; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. vcracan@scripps.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2024 May; Vol. 20 (5), pp. 594-604. Date of Electronic Publication: 2023 Oct 26.

A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis.

Autor: Abdulaziz EN; Redox Biology and Metabolism Laboratory, Scintillon Institute, San Diego, California, USA., Bell TA; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Rashid B; Faculty of Chemistry, University of Kaiserslautern, Kaiserslautern, Germany., Heacock ML; Redox Biology and Metabolism Laboratory, Scintillon Institute, San Diego, California, USA., Begic T; Faculty of Chemistry, University of Kaiserslautern, Kaiserslautern, Germany., Skinner OS; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, Massachusetts, USA., Yaseen MA; Department of Bioengineering, Northeastern University, Boston, Massachusetts, USA., Chao LH; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Mootha VK; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, Massachusetts, USA., Pierik AJ; Faculty of Chemistry, University of Kaiserslautern, Kaiserslautern, Germany., Cracan V; Redox Biology and Metabolism Laboratory, Scintillon Institute, San Diego, California, USA; Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA. Electronic address: vcracan@scripps.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Aug; Vol. 298 (8), pp. 102210. Date of Electronic Publication: 2022 Jun 30.

Understanding exposures and latent disease risk within the National Institute of Environmental Health Sciences Superfund Research Program.

Autor: Amolegbe SM; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA., Carlin DJ; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA., Henry HF; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA., Heacock ML; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA., Trottier BA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA., Suk WA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC 27560, USA.

Publikováno v: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2022 Apr; Vol. 247 (7), pp. 529-537. Date of Electronic Publication: 2022 Mar 07.

Sharing SRP data to reduce environmentally associated disease and promote transdisciplinary research.

Autor: Heacock ML; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Amolegbe SM; MDB, Inc., Durham, NC, USA., Skalla LA; MDB, Inc., Durham, NC, USA., Trottier BA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Carlin DJ; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Henry HF; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Lopez AR; MDB, Inc., Durham, NC, USA., Duncan CG; National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Lawler CP; National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Balshaw DM; National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA., Suk WA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, NC, USA.

Publikováno v: Reviews on environmental health [Rev Environ Health] 2020 Jun 25; Vol. 35 (2), pp. 111-122.

Assessing the Economic and Societal Benefits of SRP-Funded Research.

Autor: Suk WA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA., Heacock ML; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA., Trottier BA; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA., Amolegbe SM; MDB, Inc., Durham, North Carolina, USA., Avakian MD; MDB, Inc., Durham, North Carolina, USA., Henry HF; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA., Carlin DJ; Superfund Research Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA., Reed LG; MDB, Inc., Durham, North Carolina, USA.

Publikováno v: Environmental health perspectives [Environ Health Perspect] 2018 Jun 15; Vol. 126 (6), pp. 065002. Date of Electronic Publication: 2018 Jun 15 (Print Publication: 2018).