Zobrazeno 1 - 10
of 45
pro vyhledávání: '"He-yi Zhang"'
Autor:
Shan Song, Jun Qiao, Rong Zhao, Yu-Jie Lu, Can Wang, Min-Jing Chang, He-Yi Zhang, Xiao-Feng Li, Cai-Hong Wang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Osteoarthritis (OA) is a degenerative osteoarticular disease, involving genetic predisposition. How the risk variants confer the risk of OA through their effects on proteins remains largely unknown. Therefore, we aimed to discover
Externí odkaz:
https://doaj.org/article/ec9d34f2d34149ef8050ff99b2ce6580
Autor:
Qin-Yi Su, Hao-Nan Zhou, Guo-Mei Xia, Rui-Yuan Zhang, Hong-Yuan Tian, Chang Su, Yu-Xin Liu, He-Yi Zhang, Ting Cheng, Yue-Hong Huo, Qian Li, Sheng-Xiao Zhang
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 2, Pp 227-237 (2024)
Abstract Introduction Currently, the cause of psoriatic arthritis (PsA) is unknown, and the effectiveness of current drug treatments is unsatisfactory. In March 2019, the US Food and Drug Administration (FDA) approved risankizumab, a humanized immuno
Externí odkaz:
https://doaj.org/article/02e8c4b1e856444593e5ab8c9f52f166
Autor:
Ting Cheng, Jia-Lin Hou, Zi-Yi Han, Xin-Lei Geng, Yao-Chen Zhang, Ke-Yi Fan, Liu Liu, He-Yi Zhang, Yue-Hong Huo, Xiao-Feng Li, Sheng-Xiao Zhang
Publikováno v:
Experimental Gerontology, Vol 191, Iss , Pp 112434- (2024)
Background: Observational evidence suggests that type 1 diabetes mellitus (T1DM) is associated with the risk of osteoporosis (OP). Nevertheless, it is not apparent whether these correlations indicate a causal relationship. To elucidate the causal rel
Externí odkaz:
https://doaj.org/article/d0d945d28a2a48e0958470e4829eb77e
Autor:
Rong Zhao, Yi-Wen Zhang, Jin-Cheng Guo, Jun Qiao, Shan Song, Ting-Ting Zhang, He-Yi Zhang, Sheng-Xiao Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background/purpose: Previous epidemiological studies have associated interstitial lung disease (ILD) with rheumatoid arthritis (RA), yet the causality of this relationship remains uncertain. This study aimed to investigate the genetic causal link bet
Externí odkaz:
https://doaj.org/article/34f5e339affc43bda56bdbe5bf868a99
Autor:
Jin-Mei You, Yao-Chen Zhang, Ke-Yi Fan, Shang-Kai Bai, Zi-Yu Zhang, He-Yi Zhang, Ting Cheng, Yue-Hong Huo, Cai-Hong Wang, Xiao-Feng Li, Sheng-Xiao Zhang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease characterized by the accumulation of leukocytes and inflammatory mediators within the synovial tissue. Leukocyte counts are proposed to play a role in the pathogenesis of RA. However, the ca
Externí odkaz:
https://doaj.org/article/a4467c293b784bc496a170a322415be1
Autor:
Sheng-Xiao Zhang, Hao-Ran Chen, Jia Wang, Hong-Fang Shao, Ting Cheng, Ruo-Meng Pei, Qin-Yi Su, He-Yi Zhang, Xiao-Feng Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImmunotherapy targeting factors related to immune imbalance has been widely employed for RA treatment. This study aimed to evaluate the efficacy and safety of low-dose interleukin (IL)-2 combined with tocilizumab (TCZ), a biologics targetin
Externí odkaz:
https://doaj.org/article/193bff2f11244cda91d0ec1adc9d4576
Publikováno v:
Basic and Clinical Andrology, Vol 33, Iss 1, Pp 1-9 (2023)
Abstract Background As one of the most critical proteins in the JAK/STAT signaling pathway, Janus kinase 2 (JAK2) is involved in many biological processes and diseases. Several observational studies have reported the role of JAK2 in erectile dysfunct
Externí odkaz:
https://doaj.org/article/600144084684460ba1cd4f59f2a8b5bc
Publikováno v:
Sensors, Vol 24, Iss 10, p 3066 (2024)
Soybean is grown worldwide for its high protein and oil content. Weeds compete fiercely for resources, which affects soybean yields. Because of the progressive enhancement of weed resistance to herbicides and the quickly increasing cost of manual wee
Externí odkaz:
https://doaj.org/article/6d3b7285a77041f7a8b1315a2853370b
Autor:
Yao-Chen Zhang, Ke-Yi Fan, Qi Wang, Jing-Xi Hu, Qian Wang, He-Yi Zhang, Shan Song, Rong Zhao, Jun Qiao, Sheng-Xiao Zhang
Publikováno v:
Neurology and Therapy, Vol 12, Iss 3, Pp 751-762 (2023)
Abstract Background Results from observational studies indicate an association between circulating levels of mammalian target of rapamycin (mTOR)-dependent circulating proteins and the risk of multiple sclerosis (MS). However, a causal association ha
Externí odkaz:
https://doaj.org/article/7571dd8b03eb45288d12d19f2f215478
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Tomato is a globally grown vegetable crop with high economic and nutritional values. Tomato production is being threatened by weeds. This effect is more pronounced in the early stages of tomato plant growth. Thus weed management in the early stages o
Externí odkaz:
https://doaj.org/article/b94dcdcccd344f26988f03cb273cb4a5