Zobrazeno 1 - 10
of 14
pro vyhledávání: '"He-Zhou Guo"'
Autor:
Shan-He Yu, Kang-Yong Zhu, Juan Chen, Xiang-Zhen Liu, Peng-Fei Xu, Wu Zhang, Li Yan, He-Zhou Guo, Jiang Zhu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Histone demethylase JMJD3 is known to be oncogenic in preleukemic states and T-cell acute lymphocytic leukemia. Here, the authors show that in some acute myeloid leukemia subsets, JMJD3 can actually act as a potential oncorepressor via mediation of C
Externí odkaz:
https://doaj.org/article/c51536513a7740679eae444e92adbac3
Autor:
Shan-He Yu, Xiang-Qin Weng, Wu Zhang, Li-Ting Niu, Jun Shi, Wan-Ting Qiang, Yi Zhang, Yuanyuan Tian, Shao-Yan Hu, Jiang Zhu, Meng-Meng Huang, Zi-Hua Guo, Hui Yang, Juan Chen, He-Zhou Guo
Publikováno v:
Science Advances
Description
A stimulated proinflammatory feature of leukemic progenitors facilitates their survival and immune evasion after chemotherapy.
Chemotherapy can effectively reduce the leukemic burden and restore immune cell production in most ac
A stimulated proinflammatory feature of leukemic progenitors facilitates their survival and immune evasion after chemotherapy.
Chemotherapy can effectively reduce the leukemic burden and restore immune cell production in most ac
Autor:
Juan Wang, Shan-He Yu, Wu Zhang, Hui Yang, Jiang Zhu, Wan-Ting Qiang, Juan Chen, Li-Ting Niu, He-Zhou Guo
Publikováno v:
The FASEB Journal. 33:9565-9576
Secreted proteins provide crucial signals that have been implicated in the development of acute myeloid leukemia (AML) in the bone marrow microenvironment. Here we identify aberrant expressions of inflammatory IL-17B and its receptor (IL-17RB) in hum
Autor:
Wu Zhang, Jiang Zhu, Zhu Chen, Jian Lin, Hui Yang, Sai-Juan Chen, Hong-Xin Zhang, He-Zhou Guo, Jun-Mei Zhao, Xian-Yang Li
Publikováno v:
The Journal of Immunology. 199:119-128
Innate immunity activation by viral RNA–primed retinoid acid inducible gene-I (Rig-I) in CD4+ T cells antagonizes TGFβ signaling to suppress the differentiation of regulatory T cells (Tregs). However, how viral RNA–unliganded Rig-I (apo–Rig-I)
Autor:
He-Zhou Guo1,2, Zi-Hua Guo1, Shan-He Yu1, Li-Ting Niu1, Wan-Ting Qiang1, Meng-Meng Huang1, Yuan-Yuan Tian3, Juan Chen1, Hui Yang1, Xiang-Qin Weng1, Yi Zhang3, Wu Zhang1, Shao-Yan Hu4, Jun Shi2 junshi@sjtu.edu.cn, Jiang Zhu1,5 zhujiang@shsmu.edu.cn
Publikováno v:
Science Advances. 10/8/2021, Vol. 7 Issue 41, p1-15. 15p.
Autor:
Zhu Chen, Jiang Zhu, Wu Zhang, Meng-Lei Ding, Xiaodong Xi, Xian-Yang Li, Sai-Juan Chen, He-Zhou Guo, Lei Chen, Hong-Xin Zhang, Xiaodan Ma, Xiang-Zhen Liu, Lin-Jia Jiang
Publikováno v:
Molecular Cell. 53:407-419
Retinoic acid (RA)-inducible gene I (RIG-I) is highly upregulated and functionally implicated in the RA-induced maturation of acute myeloid leukemia (AML) blasts. However, the underlying mechanism and the biological relevance of RIG-I expression to t
Autor:
He-Zhou Guo, Li-Ting Niu, Wan-Ting Qiang, Juan Chen, Juan Wang, Hui Yang, Wu Zhang, Jiang Zhu, Shan-He Yu
Publikováno v:
FASEB Journal; Aug2019, Vol. 33 Issue 8, p9565-9576, 12p
Publikováno v:
Cell Death & Disease
All-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO) administration leads to granulocytic maturation and/or apoptosis of acute promyelocytic leukemia (APL) cells mainly by targeting promyelocytic leukemia/retinoic acid receptor alpha (PML/RAR
Autor:
Hui Yang1, He-Zhou Guo2, Xian-Yang Li1, Jian Lin2, Wu Zhang1, Jun-Mei Zhao1, Hong-Xin Zhang1, Sai-Juan Chen1,3, Zhu Chen1,3, Jiang Zhu1,2,3 zhujiang@shsmu.edu.cn
Publikováno v:
Journal of Immunology. 7/1/2017, Vol. 199 Issue 1, p119-128. 10p.
Publikováno v:
Molecular & Cellular Oncology
Retinoic acid inducible gene-I (RIG-I), named for the observation that its mRNA expression is highly upregulated in the progression of all-trans retinoic acid (ATRA)-induced maturation of acute promyelocytic leukemia (APL) cells, has been well docume