Zobrazeno 1 - 3
of 3
pro vyhledávání: '"He Tian Tony Chen"'
Autor:
Lina Liu, Ana Vujovic, Nandan P. Deshpande, Shashank Sathe, Govardhan Anande, He Tian Tony Chen, Joshua Xu, Mark D. Minden, Gene W. Yeo, Ashwin Unnikrishnan, Kristin J. Hope, Yu Lu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Leukemic stem cells (LSCs) drive chemoresistance and relapse in acute myeloid leukemia. Here, the authors show that the splicing factor RBM17 supports LSCs through avoiding nonsense-mediated decay of pro-leukaemic factors such as the translation init
Externí odkaz:
https://doaj.org/article/85c36ded2db34489ade4dbffb3dc816b
Autor:
Ava Keyvani Chahi, Muluken S. Belew, Joshua Xu, He Tian Tony Chen, Stefan Rentas, Veronique Voisin, Gabriela Krivdova, Eric Lechman, Sajid A. Marhon, Daniel D. De Carvalho, John E. Dick, Gary D. Bader, Kristin J. Hope
Publikováno v:
Blood. 140:992-1008
Hematopoietic stem cell (HSC) dormancy is understood as supportive of HSC function and its long-term integrity. Although regulation of stress responses incurred as a result of HSC activation is recognized as important in maintaining stem cell functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c7c0a928ffbfa41375aa2c6c2a365
https://doi.org/10.1182/blood.2021014698
https://doi.org/10.1182/blood.2021014698
Autor:
Lina Liu, Ana Vujovic, Nandan P. Deshpande, Shashank Sathe, Govardhan Anande, He Tian Tony Chen, Joshua Xu, Mark D. Minden, Gene W. Yeo, Ashwin Unnikrishnan, Kristin J. Hope, Yu Lu
Publikováno v:
Nature communications. 13(1)
Chemo-resistance in acute myeloid leukemia (AML) patients is driven by leukemic stem cells (LSCs) resulting in high rates of relapse and low overall survival. Here, we demonstrate that upregulation of the splicing factor, RBM17 preferentially marks a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616b81675619b0bded3874cd95087600
https://pubmed.ncbi.nlm.nih.gov/35781533
https://pubmed.ncbi.nlm.nih.gov/35781533