Výsledky vyhledávání

Akademický článek

Downregulation of protease activated receptor expression and cytokine production in P815 cells by RNA interference

Autor: Wu Shandong, Zhang Huiyun, Qiao Liya, He Shaoheng

Publikováno v: BMC Cell Biology, Vol 10, Iss 1, p 62 (2009)

Abstract Background Protease-activated receptors (PAR) are seven transmembrane G-coupled receptors comprising four genes (PAR-1 ~ PAR-4). Mast cell has been identified to be able to express PARs and release an array of cytokines upon activation. Rece

Externí odkaz: https://doaj.org/article/881209eeb7454600b4f19aa4395386c7

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Akademický článek

Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF

Autor: Zhang Wei, Lin Liyan, Zhang Huiyun, Wei Jifu, Yang Haiwei, He Shaoheng

Publikováno v: BMC Cell Biology, Vol 10, Iss 1, p 37 (2009)

Abstract Backgroud Recently, mast cells have been recognized to express several Toll-like receptors (TLRs) on their membrane surfaces, and granulocyte-macrophage colony-stimulating factor (GM-CSF) was reported to be able to alter expression of TLRs a

Externí odkaz: https://doaj.org/article/9f1ec81c8f3440fdadbf993bc469736e

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Akademický článek

Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of JAK/STAT3 signaling pathway in MMP-9 release

Autor: He Shaoheng, Luo Jianmin, Wang Li

Publikováno v: BMC Cell Biology, Vol 8, Iss 1, p 14 (2007)

Abstract Background It has been recognized that dermal fibroblasts and matrix metalloproteases (MMP) play crucial roles in wound healing process in skin. Thrombin was found to stimulate IL-8 release from human dermal fibroblasts (HDFs). However, litt

Externí odkaz: https://doaj.org/article/a7b12e349d76498aad686b24ed8d8d8a

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Akademický článek

Induction of release and up-regulated gene expression of interleukin (IL)-8 in A549 cells by serine proteinases

Autor: He Shaoheng, Zheng Yanshan, Wang Haiyan

Publikováno v: BMC Cell Biology, Vol 7, Iss 1, p 22 (2006)

Abstract Background Hypersecretion of cytokines and serine proteinases has been observed in asthma. Since protease-activated receptors (PARs) are receptors of several serine proteinases and airway epithelial cells are a major source of cytokines, the

Externí odkaz: https://doaj.org/article/ee59d6b6424142bcb87c54fae395f5f9

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