Zobrazeno 1 - 10
of 80
pro vyhledávání: '"He N. Xu"'
Autor:
Connor Leek, Abiud Cantu, Shilpa Sonti, Manuel Cantu Gutierrez, Laurie Eldredge, Eniko Sajti, He N. Xu, Krithika Lingappan
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103296- (2024)
The lung macrophages play a crucial role in health and disease. Sexual dimorphism significantly impacts the phenotype and function of tissue-resident macrophages. The primary mechanisms responsible for sexually dimorphic outcomes in bronchopulmonary
Externí odkaz:
https://doaj.org/article/61d7856613d346e6afb2dbc5bfa6ac0b
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 17, Iss 01 (2024)
Adenine nucleotide translocator (ANT) is a mitochondrial protein involved in the exchange of ADP and ATP across the mitochondrial inner membrane. It plays a crucial role in cellular energy metabolism by facilitating the transport of ATP synthesized w
Externí odkaz:
https://doaj.org/article/aa7c59576fe14effb767de749bf4237a
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 546 (2024)
Emerging data indicate that lung macrophages (LM) may provide a novel biomarker to classify disease endotypes in bronchopulmonary dysplasia (BPD), a form of infant chronic lung disease, and that augmentation of the LM phenotype may be a potential the
Externí odkaz:
https://doaj.org/article/f3ba5817649f44478be2ef2467c3502f
Autor:
Brandon Gaitan, Collin Inglut, Udayakumar Kanniyappan, He N. Xu, Emily F. Conant, Lucas Frankle, Lin Z. Li, Yu Chen, Huang-Chiao Huang
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1097 (2022)
Breast cancer is the most diagnosed cancer type in women, with it being the second most deadly cancer in terms of total yearly mortality. Due to the prevalence of this disease, better methods are needed for both detection and treatment. Reduced nicot
Externí odkaz:
https://doaj.org/article/0977d47ef25d4728b72ba3e5b42534ae
Autor:
He N. Xu, Sarah Gourmaud, Allison Podsednik, Xiaofan Li, Huaqing Zhao, Frances E. Jensen, Delia M. Talos, Lin Z. Li
Publikováno v:
Metabolites, Vol 12, Iss 9, p 786 (2022)
A substantial decline in nicotinamide adenine dinucleotide (NAD) has been reported in brain tissue homogenates or neurons isolated from Alzheimer’s disease (AD) models. NAD, together with flavin adenine dinucleotide (FAD), critically supports energ
Externí odkaz:
https://doaj.org/article/231181e9199b4118863cc56773f60861
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 767 (2021)
Employing the optical redox imaging technique, we previously identified a significant redox shift of nicotinamide adenine dinucleotide (NAD and the reduced form NADH) in freshly isolated alveolar macrophages (AM) from ozone-exposed mice. The goal her
Externí odkaz:
https://doaj.org/article/b474540df71d43fe89517c970caf177a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5563 (2021)
We evaluated the utility of optical redox imaging (ORI) to identify the therapeutic response of triple-negative breast cancers (TNBC) under various drug treatments. Cultured HCC1806 and MDA-MB-231 cells treated with FK866 (nicotinamide phosphoribosyl
Externí odkaz:
https://doaj.org/article/23969edd141344cfaf5555b9548f03fa
Autor:
Yoelvis Garcia-Mesa, He N. Xu, Patricia Vance, Analise L. Gruenewald, Rolando Garza, Cecily Midkiff, Xavier Alvarez-Hernandez, David J. Irwin, Alexander J. Gill, Dennis L. Kolson
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 416 (2021)
Dimethyl fumarate (DMF), an antioxidant/anti-inflammatory drug approved for the treatment of multiple sclerosis, induces antioxidant enzymes, in part through transcriptional upregulation. We hypothesized that DMF administration to simian immunodefici
Externí odkaz:
https://doaj.org/article/798899dc7e0f4af6bbdd009cbcb004d2
Autor:
He N. Xu, Zhenwu Lin, Chintan K. Gandhi, Shaili Amatya, Yunhua Wang, Lin Z. Li, Joanna Floros
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 915 (2020)
Co-enzyme nicotinamide adenine dinucleotide (NAD(H)) redox plays a key role in macrophage function. Surfactant protein (SP-) A modulates the functions of alveolar macrophages (AM) and ozone (O3) exposure in the presence or absence of SP-A and reduces
Externí odkaz:
https://doaj.org/article/78c0a83e2e1149cb8caed46ae1e0b7ae
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 7, Iss 2, Pp 1350045-1-1350045-10 (2014)
The heart requires continuous ATP availability that is generated in the mitochondria. Although studies using the cell culture and perfused organ models have been carried out to investigate the biochemistry in the mitochondria in response to a change
Externí odkaz:
https://doaj.org/article/12eaa410c87e4192a3c0fb417c849850