Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hazim Aljewari"'
Autor:
Abelline Fionah, Cannon Hackett, Hazim Aljewari, Laura Brady, Faisal Alqhtani, Isabel C. Escobar, Audie K. Thompson
Publikováno v:
Toxins, Vol 14, Iss 4, p 231 (2022)
Microcystin-LR (MC-LR) is a toxin produced by cyanobacteria that can bloom in freshwater supplies. This study describes a new strategy for remediation of MC-LR that combines linearization of the toxin using microcystinase A, MlrA, enzyme with rejecti
Externí odkaz:
https://doaj.org/article/de5fa80b8d4d43b094aa2e3c8e544737
Autor:
Imann Mosleh, Alireza Abbaspourrad, Xianghong Qian, Ranil Wickramasinghe, Robert R. Beitle, Christina Carbrello, Hazim Aljewari, Ahmad Reza Khosropour
Publikováno v:
ACS Applied Materials & Interfaces. 13:35019-35025
Although covalent organic frameworks (COFs) have earned significant interest in separation applications, the use of COFs in biomolecule separation remains unexplored. We examined the ionic COF Py-BPy2+-COF as an ion exchange material for biomolecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56e19fe2d61c20e26f7958845a59110
https://doi.org/10.1021/acsami.1c11270
https://doi.org/10.1021/acsami.1c11270
Autor:
Audie Thompson, Raquel de Castro, Hazim Aljewari, Felecia Nave, Olivia Solomon, Quincy C. Moore
Publikováno v:
Journal of Biomaterials and Nanobiotechnology. 11:67-81
This study investigates poly(vinyl alcohol) (PVA) membranes as controlled release micro-matrices, which can be useful in therapeutic applications for optimizing the administration of drugs. Currently, the use of hydrogels is limited by protein size.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced3e4d57c6aedc2874e3f9f5f343381
https://doi.org/10.4236/jbnb.2020.111005
https://doi.org/10.4236/jbnb.2020.111005
Autor:
Sarah O'Keefe, Pratiti Bhadra, Kwabena Duah, Guanghui Zong, Levise Tenay, Lauren Andrews, Hayden Schneider, Ashley Anderson, Zhijian Hu, Hazim Aljewari, Belinda Hall, Rachel Simmonds, Volkhard Helms, Stephen High, Wei Shi
The macrocyclic small molecule inhibitor ipomoeassin F (Ipom-F) binds to the central Sec61α subunit of the Sec61 complex and induces cytotoxicity by disrupting multiple aspects of Sec61-mediated protein biogenesis at the endoplasmic reticulum (ER).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163f3730f3118442b93730ba3ccabdfc
https://doi.org/10.26434/chemrxiv-2022-sc5xv
https://doi.org/10.26434/chemrxiv-2022-sc5xv
Autor:
McKinzie Fruchtl, Ahmed K.Ali Elmasheiti, Rita Tejada‐Vaprio, Hazim Aljewari, Imann Mosleh, Robert R. Beitle, M. Hassan Beyzavi, Rudra Palash Mukherjee, Lauren F. Greenlee, Nicholas M. Bedford
Publikováno v:
Biotechnology progressREFERENCES. 36(3)
Although peptide-enabled synthesis of nanostructures has garnered considerable interest for use in catalytic applications, it has so far been achieved mostly via Fmoc based solid phase peptide synthesis. Consequently, the potential of longer peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47559de5bbfde46fc5a9e1cd6f99a4b7
https://pubmed.ncbi.nlm.nih.gov/31895491
https://pubmed.ncbi.nlm.nih.gov/31895491
Publikováno v:
Organic Letters. 18:1674-1677
Ipomoeassin F, the flagship congener of a resin glycoside family exhibited single-digit nanomolar IC50 values against several cancer cell lines. To facilitate drug discovery based on this unique yet underexplored natural product, we performed the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e812bf1e25f54ab417109b0968da33
https://doi.org/10.1021/acs.orglett.6b00555
https://doi.org/10.1021/acs.orglett.6b00555
Publikováno v:
The Journal of Organic Chemistry. 80:9279-9291
Ipomoeassin F, a macrolide glycoresin containing an embedded disaccharide, possesses potent in vitro antitumor activity with an unknown mechanism of function. It inhibits tumor cell growth with single-digit nanomolar IC50 values, superior to many cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558cb73f33edd2f8d37d1d25df583733
https://doi.org/10.1021/acs.joc.5b01765
https://doi.org/10.1021/acs.joc.5b01765
Publikováno v:
Organic Letters; Apr2016, Vol. 18 Issue 7, p1674-1677, 4p