Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium

Autor: Hazim, Roni A., Paniagua, Antonio E., Tang, Lisa, Yang, Krista, Kim, Kristen K.O., Stiles, Linsey, Divakaruni, Ajit S., Williams, David S.

Publikováno v: In Journal of Biological Chemistry September 2022 298(9)

Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration

Autor: Esteve-Rudd, Julian, Hazim, Roni A., Diemer, Tanja, Paniagua, Antonio E., Volland, Stefanie, Umapathy, Ankita, Williams, David S.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 May . 115(21), 5468-5473.

Externí odkaz: https://www.jstor.org/stable/26509845

Microtubule Motor Transport of Organelles in a Specialized Epithelium: The RPE

Autor: Hazim, Roni A, Williams, David S

Publikováno v: Frontiers in Cell and Developmental Biology. 10

The retinal pigment epithelium (RPE) is a uniquely polarized epithelium that lies adjacent to the photoreceptor cells in the retina, and is essential for photoreceptor function and viability. Two major motile organelles present in the RPE are the mel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592760373aafcd98bedefa06f3d953b1
https://doi.org/10.3389/fcell.2022.852468

Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.

Autor: Hazim, Roni A.¹, Karumbayaram, Saravanan^2,3,4 Skarumbayaram@mednet.ucla.edu, Mei Jiang¹, Dimashkie, Anupama³, Lopes, Vanda S.¹, Li, Douran^1,5, Burgess, Barry L.¹, Vijayaraj, Preethi^4,6, Alva-Ornelas, Jackelyn A.⁷, Zack, Jerome A.^2,3,4,8, Kohn, Donald B.^2,3,4,6, Gomperts, Brigitte N.^3,4,6, Pyle, April D.^2,3,4, Lowry, William E.^3,4,5, Williams, David S.^1,9,10,11 dswilliams@ucla.edu

Publikováno v: Stem Cell Research & Therapy. 10/2/2017, Vol. 8, p1-17. 17p.

Aspects of RPE Cell Biology in Disease

Autor: Hazim, Roni

Publikováno v: Hazim, Roni. (2018). Aspects of RPE Cell Biology in Disease. UCLA: Neuroscience 004F. Retrieved from: http://www.escholarship.org/uc/item/9wd0b7mk

The RPE is a polarized epithelium, whose apical surface faces the outer segments of photoreceptor cells in the neurosensory retina, and performs numerous functions that are essential for healthy vision. In this dissertation, I investigated aspects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::6674c7eb54bc24effd76adedb95d80df
http://www.escholarship.org/uc/item/9wd0b7mk