Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hazem M. Fathy"'
Autor:
Essmat M. El-Sheref, Mohamed A. Ameen, Kamal M. El-Shaieb, Fathy F. Abdel-Latif, Asmaa I. Abdel-naser, Alan B. Brown, Stefan Bräse, Hazem M. Fathy, Iqrar Ahmad, Harun Patel, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Asmaa H. Mohamed
Publikováno v:
Molecules, Vol 27, Iss 24, p 8765 (2022)
Our investigation includes the synthesis of new naphthalene-bis-triazole-bis-quinolin-2(1H)-ones 4a–e and 7a–e via Cu-catalyzed [3 + 2] cycloadditions of 4-azidoquinolin-2(1H)-ones 3a–e with 1,5-/or 1,8-bis(prop-2-yn-1-yloxy)naphthalene (2) or
Externí odkaz:
https://doaj.org/article/4e4501f3216848af8481e48ec7fe5543
Autor:
Yaseen A. M. M. Elshaier, Ashraf A. Aly, Mohamed Abdel-Aziz, Hazem M. Fathy, Alan B. Brown, Stefan Bräse, Mohamed Ramadan
Publikováno v:
Molecules, Vol 27, Iss 20, p 7126 (2022)
Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, w
Externí odkaz:
https://doaj.org/article/570488fbb7cb44e0b5d4e34471f5ac5b
Autor:
Ashraf A. Aly, Alan B. Brown, Mohamad Ramadan, Mohamed Abd El-Aziz, Stefan Bräsee, Hazem M. Fathy
Publikováno v:
ARKIVOC, Vol 2016, Iss 6, Pp 92-104 (2017)
Externí odkaz:
https://doaj.org/article/54e301a1e12a4392816caf6cfefc9190
Autor:
Alan B. Brown, Yaseen A.M.M. Elshaier, Mohamed Abd El-Aziz, Hazem M. Fathy, Stefan Bräse, Martin Nieger, Mohamed Ramadan, Ashraf A. Aly
Publikováno v:
Journal of Sulfur Chemistry. 43:215-231
Regioselective synthesis of quinolone-1,2,4-triazoles was established starting from 4-hydroxyquinol-2-ones. The strategy started by the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4e25c594f8a1e8c624863e3e7b731e
https://doi.org/10.1080/17415993.2021.2006659
https://doi.org/10.1080/17415993.2021.2006659
Autor:
Ashraf A. Aly, Mohamed Ramadan, Yaseen A.M.M. Elshaier, Alan B. Brown, Mohamed Abd El-Aziz, Hazem M. Fathy
Publikováno v:
Molecular Diversity. 26:2341-2370
The quinoline scaffold has become an important construction motif for the development of new drugs. The quinolones and their heteroannulated derivatives have high importance due to their diverse spectrum of biological activities as antifungal, anti-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e630a68158f4da8ee8db002b917172d4
https://doi.org/10.1007/s11030-021-10332-1
https://doi.org/10.1007/s11030-021-10332-1
Autor:
Yaseen A M M, Elshaier, Ashraf A, Aly, Mohamed Abd, El-Aziz, Hazem M, Fathy, Alan B, Brown, Mohamed, Ramadan
Publikováno v:
Molecular diversity. 26(4)
The quinoline scaffold has become an important construction motif for the development of new drugs. The quinolones and their heteroannulated derivatives have high importance due to their diverse spectrum of biological activities as antifungal, anti-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f52ac89e8dd5fc186ff2e25815439210
https://pubmed.ncbi.nlm.nih.gov/34698911
https://pubmed.ncbi.nlm.nih.gov/34698911
Autor:
Kevin N. Dalby, Hazem M. Fathy, Tamer S. Kaoud, Jacey R. Pridgen, Ashraf A. Aly, Mohamed Abdel-Aziz, Mohamed Ramadan, Yaseen A.M.M. Elshaier, Alan B. Brown
Publikováno v:
Bioorganic Chemistry. 116:105344
Src kinase activity controls diverse cellular functions, including cell growth, migration, adhesion, and survival. It is de-regulated in several cancers, including breast cancer, where it is highly expressed and phosphorylated. Thus, targeting Src by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a745e8be61478396ab5e259ca28b97
https://doi.org/10.1016/j.bioorg.2021.105344
https://doi.org/10.1016/j.bioorg.2021.105344
Autor:
Martin Nieger, Stefan Bräse, Hazem M. Fathy, Alan B. Brown, Mohamed Abd El-Aziz, Mohamed Ramadan, Ashraf A. Aly
Publikováno v:
Chemical Papers. 71:1409-1417
N-Arylbenzamidrazones and ethyl 2-cyano-3-ethoxybut-2-enoate reacted together in ethanol and catalyzed by triethylamine (Et3N) to give 5-amino-3-methyl-1-(aryl(phenylimino)methyl)-1H-pyrazole derivatives. Reaction of the target amidrazones with bis-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e6be82a64a6ffcf9d50bec5f281daf
https://doi.org/10.1007/s11696-017-0131-x
https://doi.org/10.1007/s11696-017-0131-x
Autor:
Stefan Braese, Ashraf A. Aly, Mohamed Abd El-Aziz, Mohamad Ramadan, Alan B. Brown, Hazem M. Fathy
Publikováno v:
ARKIVOC, Vol 2016, Iss 6, Pp 92-104 (2017)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab278e5161d90ab773f96573eb9980e
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p009.877
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p009.877
Autor:
Mohamed Ramadan, Mohamed Abd El-Aziz, Hazem M. Fathy, Alan B. Brown, Bahaa G.M. Youssif, Ashraf A. Aly, Yassin A.M.M. Elshaier
Publikováno v:
Bioorganic Chemistry. 105:104392
Pyrano[3,2-c]quinoline derivatives have been synthesized and utilized to obtain various new hetero-annulated triazolopyrimidine, containing quinoline, pyran, 1,2,4-triazine and pyrimidine in good yields. Newly synthesized compounds have been characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ab47323b7839c2bd3d0c7c93e38ad0
https://doi.org/10.1016/j.bioorg.2020.104392
https://doi.org/10.1016/j.bioorg.2020.104392