Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hazem Karabeber"'
Supplementary Methods from Relationships between LDH-A, Lactate, and Metastases in 4T1 Breast Tumors
Autor:
Jason A. Koutcher, Ronald Blasberg, Kristen L. Zakian, Sunitha Thakur, Xiaohui Ni, Hazem Karabeber, Raya Khanin, Inna Serganova, Asif Rizwan
Supplementary Methods - PDF file 158K, Supplemental methods contain both techniques and further data strengthening the manuscript. These include our Analysis of Breast Cancer Microarray Datasets, Generation of LDH-A knockdown and control cell lines a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313bbfc89d90804a31b66fb09e8220d1
https://doi.org/10.1158/1078-0432.22450928.v1
https://doi.org/10.1158/1078-0432.22450928.v1
Autor:
Jason A. Koutcher, Ronald Blasberg, Kristen L. Zakian, Sunitha Thakur, Xiaohui Ni, Hazem Karabeber, Raya Khanin, Inna Serganova, Asif Rizwan
Purpose: To investigate the relationship between lactate dehydrogenase A (LDH-A) expression, lactate concentration, cell metabolism, and metastases in murine 4T1 breast tumors.Experimental Design: Inhibition of LDH-A expression and protein levels wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb9545b43d012b9fcd2bd98a11d2e21
https://doi.org/10.1158/1078-0432.c.6522056.v1
https://doi.org/10.1158/1078-0432.c.6522056.v1
Supplementary Figures from Relationships between LDH-A, Lactate, and Metastases in 4T1 Breast Tumors
Autor:
Jason A. Koutcher, Ronald Blasberg, Kristen L. Zakian, Sunitha Thakur, Xiaohui Ni, Hazem Karabeber, Raya Khanin, Inna Serganova, Asif Rizwan
Supplementary Figures - PDF file 259K, Figure S1. Comparison of 4T1-WT, NC and KD9 cell lines. (A) Oxylite Oxygen Consumption Rate; (B) Reactive oxygen species (ROS); (C) mitochondria level; (D) Primary tumor (~ 100 mm3) lactate concentration. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5367fb56baa507252047bcb7cdb33b
https://doi.org/10.1158/1078-0432.22450931.v1
https://doi.org/10.1158/1078-0432.22450931.v1
Autor:
Ryan M. Davis, Massimiliano Spaliviero, Christopher H. Contag, Volker Neuschmelting, Yoomi Lee, Sanjiv S. Gambhir, Yagnesh Tailor, Matt van de Rijn, Moritz F. Kircher, Stephan Rogalla, Jeon Woong Kang, Yoku Hayakawa, Hazem Karabeber, Stefan Harmsen, Julie R. White, Ruimin Huang, Ricardo Toledo-Crow, Timothy C. Wang, Jason M. Samii
Cancers of the gastrointestinal (GI) tract are among the most frequent and most lethal cancers worldwide. An important reason for this high mortality is that early disease is typically asymptomatic, and patients often present with advanced, incurable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc5fcd775d173124bc11481718ccadf
https://europepmc.org/articles/PMC6428194/
https://europepmc.org/articles/PMC6428194/
Autor:
Ruimin Huang, Stefan Harmsen, Moritz F. Kircher, Kenneth L. Pitter, Jason M. Samii, Eric C. Holland, Hazem Karabeber
Publikováno v:
Theranostics
The dismal prognosis of patients with malignant brain tumors such as glioblastoma multiforme (GBM) is attributed mostly to their diffuse growth pattern and early microscopic tumor spread to distant regions of the brain. Because the microscopic tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d8a6eae3ea302e36b2099bab648efd
https://doi.org/10.7150/thno.13842
https://doi.org/10.7150/thno.13842
Autor:
Chun-Hao Huang, Darjus F. Tschaharganeh, Lorenzo Di Cesare Mannelli, Chrysafis Andreou, Scott W. Lowe, Hazem Karabeber, Moritz F. Kircher, Pasquale Iacono, Rivka R. Colen, Volker Neuschmelting, Anton Oseledchyk
Publikováno v:
ACS nano. 10(5)
Complete surgical resection is the ideal first-line treatment for most liver malignancies. This goal would be facilitated by an intraoperative imaging method that enables more precise visualization of tumor margins and detection of otherwise invisibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205f27b65c60af0f6382e00909b4f736
https://pubmed.ncbi.nlm.nih.gov/27078225
https://pubmed.ncbi.nlm.nih.gov/27078225
Autor:
Matthew A. Wall, Massimiliano Spaliviero, Stefan Harmsen, Eric C. Holland, Stephen A. Sastra, Samuel Singer, Hazem Karabeber, Jason M. Samii, Moritz F. Kircher, Ronald G. Blasberg, Sebastien Monette, Julie R. White, Kenneth P. Olive, Ruimin Huang, Michael Saborowski, Kenneth L. Pitter, Scott W. Lowe, Rachael O'Connor
Publikováno v:
Science translational medicine. 7(271)
The inability to visualize the true extent of cancers represents a significant challenge in many areas of oncology. The margins of most cancer types are not well demarcated because the cancer diffusely infiltrates the surrounding tissues. Furthermore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93adad4760a282e934fb839c9c3fab22
https://pubmed.ncbi.nlm.nih.gov/26080692
https://pubmed.ncbi.nlm.nih.gov/26080692
Publikováno v:
Angewandte Chemie. 126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d5448900c88664000766ee192a07b31
https://doi.org/10.1002/ange.201484461
https://doi.org/10.1002/ange.201484461
Publikováno v:
Angewandte Chemie International Edition. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b7b3b93b08d9484bb1cdd5355ac5f81
https://doi.org/10.1002/anie.201484461
https://doi.org/10.1002/anie.201484461
Autor:
Hazem Karabeber, Ruimin Huang, Jason M. Samii, Pasquale Iacono, Eric C. Holland, Kenneth L. Pitter, Moritz F. Kircher
Publikováno v:
ACS Nano
ACS Nano, 8 (10). pp. 9755-9766.
ACS Nano, 8 (10). pp. 9755-9766.
The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f1843c27094a1e742a4a0b8ad2668c
https://pubmed.ncbi.nlm.nih.gov/25093240
https://pubmed.ncbi.nlm.nih.gov/25093240