Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Hazem Ghebeh"'
Autor:
Abdulrahman Aldakheel, Mohammed Aldehaim, Mohammed Saleh Alwhaid, Renda Alhabib, Muhammad Suhail Anwar, Balqees Alzayed, Khurram Shehzad, Hazem Ghebeh, Nasser Al-Rajhi
Publikováno v:
Annals of Saudi Medicine, Vol 44, Iss 3, Pp 153-160 (2024)
BACKGROUND: Nasopharyngeal carcinoma (NPC) is a rare disease worldwide; To the best of our knowledge, there is no established standard of care specifically tailored for the adolescent population. The majority of existing research relies on retrospect
Externí odkaz:
https://doaj.org/article/75fd238131c7433fad5f5251cd2e8d8e
Autor:
Marwa Elfoly, Jumanah Y. Mirza, Ayodele Alaiya, Amal A. Al-Hazzani, Asma Tulbah, Monther Al-Alwan, Hazem Ghebeh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background PD-L1 intrinsically promotes tumor progression through multiple mechanisms, which potentially leads to resistance to anti-PD-1/PD-L1 therapies. The intrinsic effect of PD-L1 on breast cancer (BC) cell proliferation has not been fu
Externí odkaz:
https://doaj.org/article/f566893f991f499ea6cf467f7bb0d987
Autor:
Bandar Al-Saud, Huda Alajlan, Hibah Alruwaili, Latifa Almoaibed, Amer Al-Mazrou, Hazem Ghebeh, Monther Al-Alwan, Anas M. Alazami
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mutations in STK4 (MST1) are implicated in a form of autosomal recessive combined immunodeficiency, resulting in recurrent infections (especially Epstein-Barr virus viremia), autoimmunity, and cardiac malformations. Here we report a patient with an a
Externí odkaz:
https://doaj.org/article/33220447d3c24bbabe14445399aba4dc
Autor:
Reem H. AlMalki, Huda K. Al-Nasrallah, Alanoud Aldossry, Rayanah Barnawi, Samiyah Al-Khaldi, Sheema Almozyan, Mysoon M. Al-Ansari, Hazem Ghebeh, Anas M. Abdel Rahman, Monther Al-Alwan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7891 (2024)
Omics technologies provide useful tools for the identification of novel biomarkers in many diseases, including breast cancer, which is the most diagnosed cancer in women worldwide. We and others have reported a central role for the actin-bundling pro
Externí odkaz:
https://doaj.org/article/8f2c1f2d69684e50ade8dc63f052dd8e
Autor:
Shouki Bazarbashi, Mahmoud A. Elshenawy, Ahmed Badran, Ali Aljubran, Ahmed Alzahrani, Hadeel Almanea, Abdullah Alsuhaibani, Ahmed Alashwah, Mohamed Neimatallah, Alaa Abduljabbar, Luai Ashari, Samar Alhomoud, Hazem Ghebeh, Tusneem Elhassan, Nasser Alsanea, Mohammed Mohiuddin
Publikováno v:
Cancer Medicine, Vol 11, Iss 10, Pp 2056-2066 (2022)
Abstract Introduction Gemcitabine is a well‐known radiosensitizer. Herein, we tested the efficacy and toxicity of preoperative concurrent infusional gemcitabine and radiotherapy in locally advanced rectal cancer. Patients and Methods This was a pha
Externí odkaz:
https://doaj.org/article/0e12e351a0ec409f90b34578dcb818b7
Autor:
Hazem Ghebeh, Adher Al-Sayed, Riham Eiada, Leilani Cabangon, Dahish Ajarim, Kausar Suleman, Asma Tulbah, Taher Al-Tweigeri
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Therapeutic anti-PD-L1 antibodies are safe as a monotherapy, albeit with minimal efficacy in triple-negative breast cancer (TNBC). This trial aimed to test the safety and efficacy of Durvalumab and Paclitaxel in metastatic TNBC. In this open
Externí odkaz:
https://doaj.org/article/4082da344ce44ce6b8b8a7859e11152b
Autor:
Nasser Al-Rajhi, Hussein Soudy, Shoaib A. Ahmed, Tusneem Elhassan, Shamayel F. Mohammed, Hatim A. Khoja, Hazem Ghebeh
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Locally advanced nasopharyngeal carcinoma (LA-NPC) is a relatively rare disease in the west but more common in East Asia and areas of the Middle East like Saudi Arabia. Despite the advances in radiation therapy techniques, some pa
Externí odkaz:
https://doaj.org/article/8243831149ab44ecb2a27061225b56c1
Autor:
Rayanah Barnawi, Samiyah Al-Khaldi, Tala Bakheet, Mohannad Fallatah, Ayodele Alaiya, Hazem Ghebeh, Monther Al-Alwan
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Cancer stem cells (CSCs), a rare population of tumor cells with high self-renewability potential, have gained increasing attention due to their contribution to chemoresistance and metastasis. We have previously demonstrated a critical role for the ac
Externí odkaz:
https://doaj.org/article/51f9542c9e604e6f86777feb6115e939
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The T-cell inhibitory molecule PD-L1 is expressed on a fraction of breast cancer cells. The distribution of PD-L1 on the different subpopulations of breast cancer cells is not well-defined. Our aim was to study the expression level of PD-L1 on breast
Externí odkaz:
https://doaj.org/article/b081a7549cd8432a87c648ed05a3cd5e
Autor:
Rayanah Barnawi, Samiyah Al-Khaldi, Salma Majid, Amal Qattan, Tala Bakheet, Mohannad Fallatah, Hazem Ghebeh, Nehad M. Alajez, Monther Al-Alwan
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1228 (2021)
Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative
Externí odkaz:
https://doaj.org/article/2b9d45e3176c411cab455d3b094c7abe