Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Hazem E, Hassan"'
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 8, Pp 1323-1330 (2023)
Abstract Recently, digital health technologies (DHTs) and digital biomarkers have gained a lot of traction in clinical investigations, motivating sponsors, investigators, and regulators to discuss and implement integrated approaches for deploying DHT
Externí odkaz:
https://doaj.org/article/4a9c80ec00eb4785847df54be7b4d3dd
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 301-308 (2020)
There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high‐risk children and adults. We evaluated this observation in children using literature studies conducted in infants a
Externí odkaz:
https://doaj.org/article/20a2af654d8d4840aa495b40444b2595
Autor:
Mohamed A, Kamal, Andreas, Kuznik, Luyuan, Qi, Witold, Więcek, Mohamed, Hussein, Hazem E, Hassan, Kashyap, Patel, Thomas, Obadia, Masood Khaksar, Toroghi, Daniela J, Conrado, Nidal, Al-Huniti, Roman, Casciano, Meagan P, O'Brien, Ruanne V, Barnabas, Myron S, Cohen, Patrick F, Smith
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:1224-1235
To assess the combined role of anti-viral monoclonal antibodies (mAbs) and vaccines in reducing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission and mortality in the United States, an agent-based model was developed that acco
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:635-642
Characterizing interactions between new molecular entities (NMEs) and drug transporters is a critical element of drug development that helps in assessing potential transporter-based drug-drug interactions (DDIs). However, not all NME new drug applica
Publikováno v:
Pharmaceutical Research.
Autor:
Hongbing Wang, Hazem E. Hassan, Maria R. Baer, Junran Zhang, Yao Zhang, Scott Heyward, Jingwei Xiao, William D. Hedrich
Activation of CAR improves the anticancer activity of the FC regimen in HPH/HL-60 co-culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d71b1e5a17758f43271ba4b35f00db4
https://doi.org/10.1158/1535-7163.22503342.v1
https://doi.org/10.1158/1535-7163.22503342.v1
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in
Externí odkaz:
https://doaj.org/article/10ce9312b5a44475ab5bf4d9050bb7be
Publikováno v:
The Journal of Clinical Pharmacology. 62
There are more than 7000 rare diseases affecting approximately 30 million people in the United States. More than 90% of these diseases lack approved therapies. Several challenges face the development of "orphan drugs", such as the small populations o
Publikováno v:
Journal of Advanced Pharmacy Research. 4:83-93
Objectives: An ultra-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS) assay has been developed and validated for the quantification of oxycodone in rat serum and brain tissue homogenates. Methods: A simple extraction method u
Autor:
Namasivayam Ambalavanan, Jörn-Hendrik Weitkamp, Michael L. Terrin, Hazem E. Hassan, David A. Kaufman, Natalie D. Eddington, Deborah Tuttle, Ken B. Waites, Rose M. Viscardi, Natalie L. Davis, Laurence S. Magder, Susan J. Dulkerian, Pamela Donohue
Publikováno v:
Archives of Disease in Childhood. Fetal and Neonatal Edition
ObjectiveTo test whether azithromycin eradicates Ureaplasma from the respiratory tract in preterm infants.DesignProspective, phase IIb randomised, double-blind, placebo-controlled trial.SettingSeven level III–IV US, academic, neonatal intensive car