Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Hazem E, Hassan"'
Autor:
Stephen J. DiMartino, Jingning Mei, Thomas J. Schnitzer, Haitao Gao, Simon Eng, Christine Winslow, Tina Ho, Kenneth C. Turner, Hazem E. Hassan, Yamini Patel, John D. Davis, Ngan Trinh, Angela Manley, Garen Manvelian, Michael Fetell, Ned Braunstein, Gregory P. Geba, Paula Dakin
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100533- (2024)
Background: Pain associated with osteoarthritis (OA) is frequently disabling; treatments are often ineffective or intolerable. Fasinumab selectively inhibits nerve-growth factor and has shown efficacy for the management of OA pain. Methods: In this r
Externí odkaz:
https://doaj.org/article/b32426f3f0cd496bb5fb6b08bc1eb7e3
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 8, Pp 1323-1330 (2023)
Abstract Recently, digital health technologies (DHTs) and digital biomarkers have gained a lot of traction in clinical investigations, motivating sponsors, investigators, and regulators to discuss and implement integrated approaches for deploying DHT
Externí odkaz:
https://doaj.org/article/4a9c80ec00eb4785847df54be7b4d3dd
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 301-308 (2020)
There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high‐risk children and adults. We evaluated this observation in children using literature studies conducted in infants a
Externí odkaz:
https://doaj.org/article/20a2af654d8d4840aa495b40444b2595
Autor:
Mohamed A, Kamal, Andreas, Kuznik, Luyuan, Qi, Witold, Więcek, Mohamed, Hussein, Hazem E, Hassan, Kashyap, Patel, Thomas, Obadia, Masood Khaksar, Toroghi, Daniela J, Conrado, Nidal, Al-Huniti, Roman, Casciano, Meagan P, O'Brien, Ruanne V, Barnabas, Myron S, Cohen, Patrick F, Smith
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:1224-1235
To assess the combined role of anti-viral monoclonal antibodies (mAbs) and vaccines in reducing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission and mortality in the United States, an agent-based model was developed that acco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326171910bbd94d4e905c21765f17a37
https://doi.org/10.1002/cpt.2728
https://doi.org/10.1002/cpt.2728
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:635-642
Characterizing interactions between new molecular entities (NMEs) and drug transporters is a critical element of drug development that helps in assessing potential transporter-based drug-drug interactions (DDIs). However, not all NME new drug applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40fd5894344bfbb7ac8aad7441499c7
https://doi.org/10.1002/cpt.2701
https://doi.org/10.1002/cpt.2701
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b6ebb73efe2737b175d1fcc816b735
https://doi.org/10.1007/s11095-023-03487-z
https://doi.org/10.1007/s11095-023-03487-z
Autor:
Hongbing Wang, Hazem E. Hassan, Maria R. Baer, Junran Zhang, Yao Zhang, Scott Heyward, Jingwei Xiao, William D. Hedrich
CHOP- and DOX-induced cytotoxicity in H9c2 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754b68a321404c15167387196f6655c6
https://doi.org/10.1158/1535-7163.22503339.v1
https://doi.org/10.1158/1535-7163.22503339.v1
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 5, Pp 413-425 (2016)
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in
Externí odkaz:
https://doaj.org/article/10ce9312b5a44475ab5bf4d9050bb7be
Publikováno v:
The Journal of Clinical Pharmacology. 62
There are more than 7000 rare diseases affecting approximately 30 million people in the United States. More than 90% of these diseases lack approved therapies. Several challenges face the development of "orphan drugs", such as the small populations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a8aaa832e3373b42171112a8711e40
https://doi.org/10.1002/jcph.2167
https://doi.org/10.1002/jcph.2167
Publikováno v:
Journal of Advanced Pharmacy Research. 4:83-93
Objectives: An ultra-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS) assay has been developed and validated for the quantification of oxycodone in rat serum and brain tissue homogenates. Methods: A simple extraction method u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3313004f3c127d795056c5eb3360064
https://doi.org/10.21608/aprh.2020.31331.1109
https://doi.org/10.21608/aprh.2020.31331.1109