Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hazel S. Escusa"'
Autor:
James R. Bayrer, Hongtao Wang, Roy Nattiv, Miyuki Suzawa, Hazel S. Escusa, Robert J. Fletterick, Ophir D. Klein, David D. Moore, Holly A. Ingraham
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Inflammatory bowel disease is characterised by epithelial dysfunction. Here the authors show that loss of the nuclear receptor LRH-1 leads to epithelial disruption by altering Notch signaling in mouse intestinal organoids, and that LRH-1 overexpressi
Externí odkaz:
https://doaj.org/article/90369e6a41a144aa93dc643e36748685
Autor:
Mark Fitch, David L. Silver, Andreas Stahl, Diego A Miranda, William C. Krause, Miyuki Suzawa, Marc K. Hellerstein, Hazel S. Escusa, Juat Chin Foo, Holly A. Ingraham, Edna Nyangau, Diyala S. Shihadih, Amaury Cazenave-Gassiot, Markus R. Wenk
Publikováno v:
JCI insight, vol 3, iss 5
JCI Insight, Vol 3, Iss 5 (2020)
JCI Insight, Vol 3, Iss 5 (2020)
Excess lipid accumulation is an early signature of nonalcoholic fatty liver disease (NAFLD). Although liver receptor homolog 1 (LRH-1) (encoded by NR5A2) is suppressed in human NAFLD, evidence linking this phospholipid-bound nuclear receptor to hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1e975069c33ec76d9347bb90de829d
https://europepmc.org/articles/PMC5922282/
https://europepmc.org/articles/PMC5922282/
Autor:
Miyuki Suzawa, James R. Bayrer, Ophir D. Klein, Hazel S. Escusa, David D. Moore, Holly A. Ingraham, Robert J. Fletterick, Roy Nattiv, Hongtao Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature communications, vol 9, iss 1
Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking. The nuclear receptor LRH-1 (NR5A2) is expressed in intestinal epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6383aed846629510385eb9942ea7e
https://pubmed.ncbi.nlm.nih.gov/30305617
https://pubmed.ncbi.nlm.nih.gov/30305617
Publikováno v:
Gastroenterology. 154:S-67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41aca32438a7292c5c612112da85b524
https://doi.org/10.1016/s0016-5085(18)30680-2
https://doi.org/10.1016/s0016-5085(18)30680-2