Comparing biparametric to multiparametric MRI in the diagnosis of clinically significant prostate cancer in biopsy-naive men (PRIME): a prospective, international, multicentre, non-inferiority within-patient, diagnostic yield trial protocol

Autor: Jonathan J Deeks, Chris Brew-Graves, Yemisi Takwoingi, Aiman Haider, Clare Allen, Alex Freeman, Mark Emberton, Antti Rannikko, John Wilkinson, Daniel Margolis, Enrique Gomez Gomez, Sangeet Ghai, Alex Kirkham, Veeru Kasivisvanathan, Caroline M Moore, Hazel McBain, Anders Bjartell, Paula Lorgelly, Pramit Khetrapal, Shonit Punwani, Nicola Muirhead, Ridhi Agarwal, Philip Ryan, Caroline S Clarke, Aqua Asif, Peter Albertsen, Alexander Ng, Francesco Giganti, Louise Dickinson, Jeremy Grummet, Vinson Wai-Shun Chan, Arjun Nathan, Marimo Rossiter, Réka Novotta, Tushar Narain, Antonette Andrews, Valeria Panebianco, Lance Mynderse, Adam Froemming, Naoki Takahasi, Tristan Barrett, Raphaële Renard-Penna, Vibeke Løgager, Lars Boesen, Lars Budäus, Tho Pham, Jing Yi Jessica Weng, Wim Witjes, Christien Caris, Joke Van Egmond

Publikováno v: BMJ Open, Vol 13, Iss 4 (2023)

Introduction Prostate MRI is a well-established tool for the diagnostic work-up for men with suspected prostate cancer (PCa). Current recommendations advocate the use of multiparametric MRI (mpMRI), which is composed of three sequences: T2-weighted s

Externí odkaz: https://doaj.org/article/dbc4c0513c464951a792aa55f3321290

Intra-operative assessment of cancer with x-ray phase contrast computed tomography

Autor: Thomas Partridge, Lorenzo Massimi, Paul Wolfson, Jinxing Jiang, Alberto Astolfo, Tamara Suaris, Glafkos Havariyoun, Savvas Savvidis, Charlotte J. Maughan Jones, Nargiza Djurabekova, Sam P. M. Hawker, Bennie Smit, Oliver J. Larkin, Edward Millard, Wilf Shorrock, Richard Waltham, Kai Man Alexander Ho, Hazel McBain, Ash Wilson, Anthony Peel, Zoheb Shah, Rachel L. Nelan, Harry Delaney, Ama Liyadipita, Adam P. Lavine, Khaled Dawas, Borzoueh Mohammadi, Yassar Qureshi, Manil D. Chouhan, Stuart A. Taylor, Muntzer Mughal, Marco Endrizzi, Charlotte K. Hagen, Peter R. T. Munro, Stephen W. Duffy, Louise J. Jones, Marco Novelli, Laurence B. Lovat, Ian G. Haig, David Bate, Alessando Olivo

Publikováno v: Developments in X-Ray Tomography XIV.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff2bfa4700dffb95856061a7fcbdd24c
https://doi.org/10.1117/12.2632294

OFR-2 The SPIT study: creating a saliva based epigenetic biomarker panel to diagnose oesophgeal cancer

Autor: Ho K M A, Hazel McBain, Ash Wilson, Paul Wolfson, Laurence Lovat, Timothy Stone, Vanessa Ward, Avi Rosenfeld, Aine Hogan, Margaret Duku

Publikováno v: Oral.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb1576ddb739a06a9afa03614206703b
https://doi.org/10.1136/gutjnl-2021-bsg.19

Novel epigenetic network biomarkers for early detection of esophageal cancer

Autor: Alok K, Maity, Timothy C, Stone, Vanessa, Ward, Amy P, Webster, Zhen, Yang, Aine, Hogan, Hazel, McBain, Margaraet, Duku, Kai Man Alexander, Ho, Paul, Wolfson, David G, Graham, Stephan, Beck, Andrew E, Teschendorff, Laurence B, Lovat

Publikováno v: Clinical epigenetics. 14(1)

Early detection of esophageal cancer is critical to improve survival. Whilst studies have identified biomarkers, their interpretation and validity is often confounded by cell-type heterogeneity.Here we applied systems-epigenomic and cell-type deconvo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77a1efece3e1afd406c19968e99e1965
https://pubmed.ncbi.nlm.nih.gov/35164838

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

Autor: Catherine F Houlihan, Nina Vora, Thomas Byrne, Dan Lewer, Gavin Kelly, Judith Heaney, Sonia Gandhi, Moira J Spyer, Rupert Beale, Peter Cherepanov, David Moore, Richard Gilson, Steve Gamblin, George Kassiotis, Laura E McCoy, Charles Swanton, Andrew Hayward, Eleni Nastouli, Jim Aitken, Zoe Allen, Rachel Ambler, Karen Ambrose, Emma Ashton, Alida Avola, Samutheswari Balakrishnan, Caitlin Barns-Jenkins, Genevieve Barr, Sam Barrell, Souradeep Basu, Clare Beesley, Nisha Bhardwaj, Shahnaz Bibi, Ganka Bineva-Todd, Dhruva Biswas, Michael J Blackman, Dominique Bonnet, Faye Bowker, Malgorzata Broncel, Claire Brooks, Michael D Buck, Andrew Buckton, Timothy Budd, Alana Burrell, Louise Busby, Claudio Bussi, Simon Butterworth, Fiona Byrne, Richard Byrne, Simon Caidan, Joanna Campbell, Johnathan Canton, Ana Cardoso, Nick Carter, Luiz Carvalho, Raffaella Carzaniga, Natalie Chandler, Qu Chen, Laura Churchward, Graham Clark, Bobbi Clayton, Clementina Cobolli Gigli, Zena Collins, Sally Cottrell, Margaret Crawford, Laura Cubitt, Tom Cullup, Heledd Davies, Patrick Davis, Dara Davison, Annalisa D'Avola, Vicky Dearing, Solene Debaisieux, Monica Diaz-Romero, Alison Dibbs, Jessica Diring, Paul C Driscoll, Christopher Earl, Amelia Edwards, Chris Ekin, Dimitrios Evangelopoulos, Rupert Faraway, Antony Fearns, Aaron Ferron, Efthymios Fidanis, Dan Fitz, James Fleming, Bruno Frederico, Alessandra Gaiba, Anthony Gait, Liam Gaul, Helen M Golding, Jacki Goldman, Robert Goldstone, Belen Gomez Dominguez, Hui Gong, Paul R Grant, Maria Greco, Mariana Grobler, Anabel Guedan, Maximiliano G Gutierrez, Fiona Hackett, Ross Hall, Steinar Halldorsson, Suzanne Harris, Sugera Hashim, Lyn Healy, Susanne Herbst, Graeme Hewitt, Theresa Higgins, Steve Hindmarsh, Rajnika Hirani, Joshua Hope, Elizabeth Horton, Beth Hoskins, Michael Howell, Louise Howitt, Jacqueline Hoyle, Mint R Htun, Michael Hubank, Hector Huerga Encabo, Deborah Hughes, Jane Hughes, Almaz Huseynova, Ming-Shih Hwang, Rachael Instrell, Deborah Jackson, Mariam Jamal-Hanjani, Lucy Jenkins, Ming Jiang, Mark Johnson, Leigh Jones, Nnennaya Kanu, Louise Kiely, Anastacio King Spert Teixeira, Stuart Kirk, Svend Kjaer, Ellen Knuepfer, Nikita Komarov, Paul Kotzampaltiris, Konstantinos Kousis, Tammy Krylova, Ania Kucharska, Robyn Labrum, Catherine Lambe, Michelle Lappin, Stacey-Ann Lee, Andrew Levett, Lisa Levett, Marcel Levi, Hon-Wing Liu, Sam Loughlin, Wei-Ting Lu, James I MacRae, Akshay Madoo, Julie A Marczak, Mimmi Martensson, Thomas Martinez, Bishara Marzook, John Matthews, Joachim M Matz, Samuel McCall, Fiona McKay, Edel C McNamara, Carlos M Minutti, Gita Mistry, Miriam Molina-Arcas, Beatriz Montaner, Kylie Montgomery, Catherine Moore, Anastasia Moraiti, Lucia Moreira-Teixeira, Joyita Mukherjee, Cristina Naceur-Lombardelli, Aileen Nelson, Jerome Nicod, Luke Nightingale, Stephanie Nofal, Paul Nurse, Savita Nutan, Caroline Oedekoven, Anne O'Garra, Jean D O'Leary, Jessica Olsen, Olga O'Neill, Paula Ordonez Suarez, Nicola O'Reilly, Neil Osborne, Amar Pabari, Aleksandra Pajak, Venizelos Papayannopoulos, Namita Patel, Yogen Patel, Oana Paun, Nigel Peat, Laura Peces-Barba Castano, Ana Perez Caballero, Jimena Perez-Lloret, Magali S Perrault, Abigail Perrin, Roy Poh, Enzo Z Poirier, James M Polke, Marc Pollitt, Lucia Prieto-Godino, Alize Proust, Rajvee Shah Punatar, Clinda Puvirajasinghe, Christophe Queval, Vijaya Ramachandran, Abhinay Ramaprasad, Peter Ratcliffe, Laura Reed, Caetano Reis e Sousa, Kayleigh Richardson, Sophie Ridewood, Rowenna Roberts, Angela Rodgers, Pablo Romero Clavijo, Annachiara Rosa, Alice Rossi, Chloe Roustan, Andrew Rowan, Erik Sahai, Aaron Sait, Katarzyna Sala, Theo Sanderson, Pierre Santucci, Fatima Sardar, Adam Sateriale, Jill A Saunders, Chelsea Sawyer, Anja Schlott, Edina Schweighoffer, Sandra Segura-Bayona, Joe Shaw, Gee Yen Shin, Mariana Silva Dos Santos, Margaux Silvestre, Matthew Singer, Daniel M Snell, Ok-Ryul Song, Louisa Steel, Amy Strange, Adrienne E Sullivan, Michele SY Tan, Zoe H Tautz-Davis, Effie Taylor, Gunes Taylor, Harriet B Taylor, Alison Taylor-Beadling, Fernanda Teixeira Subtil, Berta Terré Torras, Patrick Toolan-Kerr, Francesca Torelli, Tea Toteva, Moritz Treeck, Hadija Trojer, Ming-Han C Tsai, James MA Turner, Melanie Turner, Jernej Ule, Rachel Ulferts, Sharon P Vanloo, Selvaraju Veeriah, Subramanian Venkatesan, Karen Vousden, Andreas Wack, Claire Walder, Philip A Walker, Yiran Wang, Sophia Ward, Catharina Wenman, Luke Wiliams, Matthew J Williams, Wai Keong Wong, Joshua Wright, Mary Wu, Lauren Wynne, Zheng Xiang, Melvyn Yap, Julian A Zagalak, Davide Zecchin, Rachel Zillwood, Rebecca Matthews, Abigail Severn, Sajida Adam, Louise Enfield, Angela McBride, Kathleen Gärtner, Sarah Edwards, Fabiana Lorencatto, Susan Michie, Ed Manley, Maryam Shahmanesh, Hinal Lukha, Paulina Prymas, Hazel McBain, Robert Shortman, Leigh Wood, Claudia Davies, Bethany Williams, Kevin W Ng, Georgina H Cornish, Nikhil Faulkner, Andrew Riddell, Philip Hobson, Ana Agua-Doce, Kerol Bartolovic, Emma Russell, Lotte Carr, Emilie Sanchez, Daniel Frampton, Matthew Byott, Stavroula M Paraskevopoulou, Elise Crayton, Carly Meyer, Triantafylia Gkouleli, Andrea Stoltenberg, Veronica Ranieri, Tom Byrne, Fiona Roberts, Emine Hatipoglu

Publikováno v: Lancet (London, England)
The Lancet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d215f199afa63e1ea25b909a5e3844
https://pubmed.ncbi.nlm.nih.gov/32653078