Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hazel Mangan"'
Autor:
Qinyu Hao, Minxue Liu, Swapna Vidhur Daulatabad, Saba Gaffari, You Jin Song, Rajneesh Srivastava, Shivang Bhaskar, Anurupa Moitra, Hazel Mangan, Elizabeth Tseng, Rachel B Gilmore, Susan M Frier, Xin Chen, Chengliang Wang, Sui Huang, Stormy Chamberlain, Hong Jin, Jonas Korlach, Brian McStay, Saurabh Sinha, Sarath Chandra Janga, Supriya G Prasanth, Kannanganattu V Prasanth
Publikováno v:
eLife, Vol 13 (2024)
Out of the several hundred copies of rRNA genes arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ~50% remain transcriptionally inactive. NOR-associated sequences and epigenetic modifications contribute to
Externí odkaz:
https://doaj.org/article/125bf24a87b9450d9f1f38fca36d642a
Autor:
Charlotte E Rutledge, Ho-Tak Lau, Hazel Mangan, Linda L Hardy, Olaf Sunnotel, Fan Guo, Angus M MacNicol, Colum P Walsh, Diane J Lees-Murdock
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88385 (2014)
Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3'UTR of Dnmt1 mRNA identical between humans and Xenopus and investigated the
Externí odkaz:
https://doaj.org/article/ded1e919582a401c89d9eaa7a96e6861
Autor:
Qinyu Hao, Minxue Liu, Swapna Vidhur Daulatabad, Saba Gaffari, Rajneesh Srivastava, You Jin Song, Shivang Bhaskar, Anurupa Moitra, Hazel Mangan, Elizabeth Tseng, Rachel B. Gilmore, Susan M. Freier, Xin Chen, Chengliang Wang, Sui Huang, Stormy Chamberlain, Hong Jin, Jonas Korlach, Brian McStay, Saurabh Sinha, Sarath Chandra Janga, Supriya G. Prasanth, Kannanganattu V. Prasanth
Out of the several hundred copies of rRNA genes that are arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ∼50% remain transcriptionally inactive. NOR-associated sequences and epigenetic modifications con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::853f0f42a95598355aebac8008687fdc
https://doi.org/10.1101/2022.07.04.498693
https://doi.org/10.1101/2022.07.04.498693
Autor:
Brian McStay, Hazel Mangan
Publikováno v:
Genes Dev
It is unknown how ribosomal gene (rDNA) arrays from multiple chromosomal nucleolar organizers (NORs) partition within human nucleoli. Exploration of this paradigm for chromosomal organization is complicated by the shared DNA sequence composition of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da4bc8a9c3f63517b5875c28226a62f
https://doi.org/10.1101/gad.348234.121
https://doi.org/10.1101/gad.348234.121
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A detailed description of how the genome is organized within the human nucleus is a major research goal. Nucleolar organizer regions (NORs) comprising ribosomal DNA (rDNA) arrays are located on the p-arms of the five human acrocentric ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b62d65b94229c9854042a1c00dcbb8
https://doi.org/10.1073/pnas.2001812117
https://doi.org/10.1073/pnas.2001812117
Autor:
Joseph G.W. McCarter, Hazel Mangan, Marjolein van Sluis, Alice Grob, Brian McStay, Michael Ó Gailín
Publikováno v:
Genes Dev
Human nucleolar organizer regions (NORs), containing ribosomal gene (rDNA) arrays, are located on the p-arms of acrocentric chromosomes (HSA13–15, 21, and 22). Absence of these p-arms from genome references has hampered research on nucleolar format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd73e9540621c6505cbd5d62210fab32
https://doi.org/10.1101/gad.331892.119
https://doi.org/10.1101/gad.331892.119
Nucleoli are the sites of ribosome biogenesis and the largest membraneless subnuclear structures. They are intimately linked with growth and proliferation control and function as sensors of cellular stress. Nucleoli form around arrays of ribosomal ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e083d988e3bf44d8b4a953fa2a5245
http://hdl.handle.net/10379/12622
http://hdl.handle.net/10379/12622