Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hazar Awad"'
Autor:
P. Jeffrey Conn, Marion Wittmann, Susan T. Rouse, Stefania Risso Bradley, Hazar Awad, Michael J. Marino
Publikováno v:
Pharmacology & Therapeutics. 88:427-435
The basal ganglia (BG) are a set of interconnected subcortical structures that play a critical role in motor control. The BG are thought to control movements by a delicate balance of transmission through two BG circuits that connect the input and out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebaf8a0ed436fe8d3a67a634024918a
https://doi.org/10.1016/s0163-7258(00)00098-x
https://doi.org/10.1016/s0163-7258(00)00098-x
Publikováno v:
The Journal of Neuroscience. 20:7871-7879
The subthalamic nucleus (STN) is a key nucleus in the basal ganglia motor circuit that provides the major glutamatergic excitatory input to the basal ganglia output nuclei. The STN plays an important role in normal motor function, as well as in patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb997de1d72bec3dcba0a39370ec9590
https://doi.org/10.1523/jneurosci.20-21-07871.2000
https://doi.org/10.1523/jneurosci.20-21-07871.2000
Publikováno v:
Amino acids. 23(1-3)
Our current understanding of the circuitry of the basal ganglia, and the pathophysiology of Parkinson's disease has led to major breakthroughs in the treatment of this debilitating movement disorder. Unfortunately, there are significant problems with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd91030b3cd95cfd0131e6cad3a19aae
https://pubmed.ncbi.nlm.nih.gov/12373536
https://pubmed.ncbi.nlm.nih.gov/12373536
Publikováno v:
Advances in Behavioral Biology ISBN: 9781461349556
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by disabling motor impairments including tremor, rigidity, and bradykinesia. The primary pathological change giving rise to the symptoms of Parkinson’s disease is loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9273841e354dfd10e40df2e70dbd442f
https://doi.org/10.1007/978-1-4615-0179-4_58
https://doi.org/10.1007/978-1-4615-0179-4_58
Autor:
Hazar Awad-Granko, P. Jeffrey Conn
Publikováno v:
Advances in Behavioral Biology ISBN: 9781461352075
The basal ganglia are a richly interconnected set of subcortical nuclei that provide a feedback loop to wide areas of the cortex as well as descending influences to brainstem motor regions. The input nucleus of the basal ganglia is the striatum (caud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4d0627267775073e5deaf16b8d5645
https://doi.org/10.1007/978-1-4615-0715-4_13
https://doi.org/10.1007/978-1-4615-0715-4_13
Autor:
Marion Wittmann, P. Jeffrey Conn, Michael J. Marino, Hazar Awad, Stefania Risso Bradley, Susan T. Rouse
Publikováno v:
Basal Ganglia and Thalamus in Health and Movement Disorders ISBN: 9781461354543
Parkinson’s disease (PD) is a common neurodegenerative disorder afflicting over 1% of adults over age 65. The clinical syndrome that occurs in Parkinson’s patients is characterized by a disabling motor impairment that includes tremor, rigidity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1112137c7d5f384607b85daedb44770c
https://doi.org/10.1007/978-1-4615-1235-6_12
https://doi.org/10.1007/978-1-4615-1235-6_12
Autor:
Stefania Risso Bradley, Allan I. Levey, P. Jeffrey Conn, Hazar Awad, Michael J. Marino, Susan T. Rouse, Marion Wittmann
Loss of nigrostriatal dopaminergic neurons in Parkinson's disease (PD) leads to increased activity of glutamatergic neurons in the subthalamic nucleus (STN). Recent studies reveal that the resultant increase in STN-induced excitation of basal ganglia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745656a4363c1838893a99fd19c4a211
https://europepmc.org/articles/PMC6773118/
https://europepmc.org/articles/PMC6773118/