Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Haytham El Salhat"'
Autor:
Varun Sasidharan Nair, Haytham El Salhat, Rowaida Z. Taha, Anne John, Bassam R. Ali, Eyad Elkord
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background High expression of immune checkpoints in tumor microenvironment plays significant roles in inhibiting anti-tumor immunity, which is associated with poor prognosis and cancer progression. Major epigenetic modifications in both DNA
Externí odkaz:
https://doaj.org/article/e693adf168e0439da6dcb29e72aa7fa4
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory T cells (Tregs) can be antitumorigenic or pro-tumorigenic in colorectal cancer (CRC) depending on the presence of different Treg subsets with various immunosuppressive molecules. Some studies reported the phenotypic characteristics of tumo
Externí odkaz:
https://doaj.org/article/52599c9e03144d368a1ebeadcb5053d2
Autor:
Salman M Toor, Azharuddin Sajid Syed Khaja, Haytham El Salhat, Omar Bekdache, Jihad Kanbar, Mohammed Jaloudi, Eyad Elkord
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. However, limited data are available on their conclusive phenotypes and
Externí odkaz:
https://doaj.org/article/9194de9e4bf44e218705c0db8db9f010
Publikováno v:
Asian Journal of Surgery, Vol 36, Iss 1, Pp 43-52 (2013)
Giant condyloma acuminatum (GCA), originally described by Buschke and Loewenstein in 1925 as a lesion of the penis, is more rarely seen in the anorectum and is characterized by clinical malignancy in the face of histologic benignity; however, maligna
Externí odkaz:
https://doaj.org/article/1cf0159dde6a4e5499a14afd5eb19b1e
Autor:
Omar Bekdache, Lateefa Al Nuaimi, Haytham El Salhat, Vasudev Sharma, Ghodratollah Nowrasteh, Sadir J. Al Rawi
Publikováno v:
Case Reports in Surgery, Vol 2014 (2014)
Metastatic laryngeal cancer to the small bowel is extremely rare. Management of small bowel obstruction used to constitute a relative contraindication for the use of laparoscopic modality. We are reporting a case of an elderly man known to have laryn
Externí odkaz:
https://doaj.org/article/55fd1c2ef24448cfa0ad7a7ad33fb9b5
Autor:
Eyad Elkord, Anne John, Varun Sasidharan Nair, Rowaida Z. Taha, Bassam R. Ali, Haytham El Salhat
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Clinical Epigenetics
Sasidharan Nair, V, El Salhat, H, Taha, R Z, John, A, Ali, B R & Elkord, E 2018, ' DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer ', Clinical Epigenetics, vol. 10, no. 1 . https://doi.org/10.1186/s13148-018-0512-1
Clinical Epigenetics
Sasidharan Nair, V, El Salhat, H, Taha, R Z, John, A, Ali, B R & Elkord, E 2018, ' DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer ', Clinical Epigenetics, vol. 10, no. 1 . https://doi.org/10.1186/s13148-018-0512-1
Background High expression of immune checkpoints in tumor microenvironment plays significant roles in inhibiting anti-tumor immunity, which is associated with poor prognosis and cancer progression. Major epigenetic modifications in both DNA and histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe6fa23dffe872da856e1bbbc190d17
http://link.springer.com/article/10.1186/s13148-018-0512-1
http://link.springer.com/article/10.1186/s13148-018-0512-1
Autor:
Haytham El Salhat, Salman M Toor, Azharuddin Sajid Syed Khaja, Eyad Elkord, Bassam R. Ali, Issam Faour, Navid Ul Haq
Publikováno v:
Oncotarget
Khaja, A S S, Toor, S M, El Salhat, H, Faour, I, ul Haq, N, Ali, B R & Elkord, E 2017, ' Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment ', Oncotarget, vol. 8, no. 20, pp. 33159-33171 . https://doi.org/10.18632/oncotarget.16565
Khaja, A S S, Toor, S M, El Salhat, H, Faour, I, ul Haq, N, Ali, B R & Elkord, E 2017, ' Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment ', Oncotarget, vol. 8, no. 20, pp. 33159-33171 . https://doi.org/10.18632/oncotarget.16565
// Azharuddin Sajid Syed Khaja 1, 2, * , Salman M. Toor 1, 2, * , Haytham El Salhat 3, 4 , Issam Faour 4 , Navid Ul Haq 5 , Bassam R. Ali 6 , Eyad Elkord 1, 2, 7 1 Cancer Research Center, Qatar Biomedical Research Institute, College of Science and En
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39de4ca634a2e0db48b118b3378b107a
https://pubmed.ncbi.nlm.nih.gov/28388539
https://pubmed.ncbi.nlm.nih.gov/28388539
Autor:
Haytham El Salhat, Azharuddin Sajid Syed Khaja, Jihad Kanbar, Salman M Toor, Omar Bekdache, Mohammed Jaloudi, Eyad Elkord
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Toor, S M, Khaja, A S S, El Salhat, H, Bekdache, O, Kanbar, J, Jaloudi, M & Elkord, E 2016, ' Increased levels of circulating and tumor-infiltrating granulocytic myeloid cells in colorectal cancer patients ', Frontiers in Immunology, vol. 7, no. DEC, 560 . https://doi.org/10.3389/fimmu.2016.00560
Frontiers in Immunology
Toor, S M, Khaja, A S S, El Salhat, H, Bekdache, O, Kanbar, J, Jaloudi, M & Elkord, E 2016, ' Increased levels of circulating and tumor-infiltrating granulocytic myeloid cells in colorectal cancer patients ', Frontiers in Immunology, vol. 7, no. DEC, 560 . https://doi.org/10.3389/fimmu.2016.00560
Frontiers in Immunology
Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. However, limited data are available on their conclusive phenotypes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b15ae2737b2523abcfe400c9a22edd
http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00560/full
http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00560/full
Publikováno v:
Scipedia Open Access
Scipedia SL
Asian Journal of Surgery, Vol 36, Iss 1, Pp 43-52 (2013)
Scipedia SL
Asian Journal of Surgery, Vol 36, Iss 1, Pp 43-52 (2013)
SummaryGiant condyloma acuminatum (GCA), originally described by Buschke and Loewenstein in 1925 as a lesion of the penis, is more rarely seen in the anorectum and is characterized by clinical malignancy in the face of histologic benignity; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735eb9613aff84f07199561bb85d9cd9
Autor:
Devin P. Champagne, Thomas Roberts, Alia Albawardi, Basel K. al-Ramadi, Dylan E O'Sullivan, James DeGregori, Kenneth L. Jones, Maria J. Fernandez-Cabezudo, M. Jawad Hashim, Hakam El-Taji, Yassir A. Mohamed, Issam Faour, Saeeda Almarzooqi, Brock C. Christensen, Mohammed A. Jaloudi, Ghada Bashir, Adnan Kassis, Haytham El-Salhat, Mercedes Rincon
Publikováno v:
JCI Insight. 1
Despite major advances in early detection and prognosis, chemotherapy resistance is a major hurdle in the battle against breast cancer. Identifying predictive markers and understanding the mechanisms are key steps to overcoming chemoresistance. Methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9a1253b317dae713989de7b5198dad
https://doi.org/10.1172/jci.insight.86873
https://doi.org/10.1172/jci.insight.86873