Rethinking the use of germline CHEK2 mutation as a marker for PARP inhibitor sensitivity.

Autor: Hayman TJ; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.

Publikováno v: JNCI cancer spectrum [JNCI Cancer Spectr] 2024 Jul 01; Vol. 8 (4).

Dose-Volume Predictors of Radiation Pneumonitis After Thoracic Hypofractionated Radiation Therapy.

Autor: Sasse A; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Oh P; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Saeed N; Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts., Yang DX; Department of Radiation Oncology, UT Southwestern, Dallas, Texas., Hayman TJ; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Knowlton CA; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Peters GW; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Campbell A; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Laird J; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Housri N; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut., Park HS; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut. Electronic address: henry.park@yale.edu.

Publikováno v: Practical radiation oncology [Pract Radiat Oncol] 2024 Mar-Apr; Vol. 14 (2), pp. e97-e104. Date of Electronic Publication: 2023 Nov 19.

Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery.

Autor: Hayman TJ; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA., Glazer PM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 25; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 25.

STING enhances cell death through regulation of reactive oxygen species and DNA damage.

Autor: Hayman TJ; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA., Baro M; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA., MacNeil T; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Phoomak C; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA., Aung TN; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Cui W; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA., Leach K; F-Star Therapeutics, Cambridge, MA, USA., Iyer R; F-Star Therapeutics, Cambridge, MA, USA., Challa S; F-Star Therapeutics, Cambridge, MA, USA., Sandoval-Schaefer T; Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA., Burtness BA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA., Contessa JN; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA. Joseph.Contessa@yale.edu.; Department of Pharmacology, Yale University, New Haven, CT, USA. Joseph.Contessa@yale.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Apr 19; Vol. 12 (1), pp. 2327. Date of Electronic Publication: 2021 Apr 19.

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses.

Autor: Hayman TJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Hsu AC; Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia., Kolesnik TB; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia., Dagley LF; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Willemsen J; Research Group Dynamics of Early Viral Infection and the Innate Antiviral Response, Division Virus-Associated Carcinogenesis (F170), German Cancer Research Center (DKFZ), Heidelberg, Germany., Tate MD; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular Translational Science, School of Clinical Sciences, Monash University, Clayton, VIC, Australia., Baker PJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Kershaw NJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Kedzierski L; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia., Webb AI; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Wark PA; Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia.; Centre for Inflammation, Centenary Institute, The University of Technology Sydney, Sydney, NSW, Australia., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia., Masters SL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Belz GT; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Binder M; Research Group Dynamics of Early Viral Infection and the Innate Antiviral Response, Division Virus-Associated Carcinogenesis (F170), German Cancer Research Center (DKFZ), Heidelberg, Germany., Hansbro PM; Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia.; Centre for Inflammation, Centenary Institute, The University of Technology Sydney, Sydney, NSW, Australia., Nicola NA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Nicholson SE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.

Publikováno v: Immunology and cell biology [Immunol Cell Biol] 2019 Oct; Vol. 97 (9), pp. 840-852. Date of Electronic Publication: 2019 Aug 19.