Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hayley McMillan"'
Autor:
Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan, John Gamble, Yvonne Dombrowski, Paul Moynagh, David Brough, Fionnuala T. Lundy, Susan D. Brain, Ikhlas A. El Karim
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1073 (2021)
This study investigates the role of transient receptor potential ankyrin 1 (TRPA1) in murine temporomandibular joint (TMJ) inflammatory hyperalgesia and the influence of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome. Two distinct muri
Externí odkaz:
https://doaj.org/article/26fbdb45b27d4d6c906fb94d82b206c3
Publikováno v:
Colorectal Disease. 25:794-805
Autor:
Kienan I. Savage, Grant S. Stewart, D. Paul Harkin, Ken I. Mills, Melissa J. La Bonte, Cheryl Latimer, Fabio G. Liberante, Hayley McMillan, Gareth W. Irwin, Satpal S. Jhujh, Eliana M. Barros, Katrina M. Lappin
Supplementary Data from Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e250212f00f5cee0275162a86dd3d0
https://doi.org/10.1158/0008-5472.22430763
https://doi.org/10.1158/0008-5472.22430763
Autor:
Kienan I. Savage, Grant S. Stewart, D. Paul Harkin, Ken I. Mills, Melissa J. La Bonte, Cheryl Latimer, Fabio G. Liberante, Hayley McMillan, Gareth W. Irwin, Satpal S. Jhujh, Eliana M. Barros, Katrina M. Lappin
Mutations in SF3B1 have been identified across several cancer types. This key spliceosome component promotes the efficient mRNA splicing of thousands of genes including those with crucial roles in the cellular response to DNA damage. Here, we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364cc5b93440e42b205c4d417aa934cb
https://doi.org/10.1158/0008-5472.c.6513714.v1
https://doi.org/10.1158/0008-5472.c.6513714.v1
Autor:
Kienan I. Savage, Grant S. Stewart, D. Paul Harkin, Ken I. Mills, Melissa J. La Bonte, Cheryl Latimer, Fabio G. Liberante, Hayley McMillan, Gareth W. Irwin, Satpal S. Jhujh, Eliana M. Barros, Katrina M. Lappin
Supplementary Table from Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8b72cb731bca85602ae22e3e680e94
https://doi.org/10.1158/0008-5472.22430757
https://doi.org/10.1158/0008-5472.22430757
Autor:
Katrina M. Lappin, Eliana M. Barros, Satpal S. Jhujh, Gareth W. Irwin, Hayley McMillan, Fabio G. Liberante, Cheryl Latimer, Melissa J. La Bonte, Ken I. Mills, D. Paul Harkin, Grant S. Stewart, Kienan I. Savage
Publikováno v:
Lappin, K M, Barros, E M, Jhujh, S S, Irwin, G W, McMillan, H, Liberante, F G, Latimer, C, LaBonte, M J, Mills, K I, Harkin, D P, Stewart, G S & Savage, K I 2022, ' Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors ', Cancer Research, vol. 82, no. 5, pp. 819-830 . https://doi.org/10.1158/0008-5472.CAN-21-1843
Cancer Res
Cancer Res
Mutations in SF3B1 have been identified across several cancer types. This key spliceosome component promotes the efficient mRNA splicing of thousands of genes including those with crucial roles in the cellular response to DNA damage. Here, we demonst
Autor:
Hayley, McMillan, Uyen G, Vo, Jana-Lee, Moss, Ian P, Barry, David C, Bosanquet, Toby, Richards
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.
Surgical site infections are common following colorectal operations. Clinical trials suggest that closed incision negative pressure wound therapy (ciNPWT) may reduce surgical site infection (SSI) compared to a 'standard of care' group. However wound
Autor:
Hayley McMillan, Nathan R. Paisley, Christopher M. Tonge, Jade Poisson, Sarah V. Halldorson, Ethan R. Sauvé, Zachary M. Hudson
Publikováno v:
Macromolecules. 54:2466-2476
A series of acrylic donor and acceptor monomers were prepared to investigate the effect of electronic and structural changes on the through-space charge-transfer (TSCT) thermally activated delayed ...
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandREFERENCES. 23(11)
Autor:
Bhumika, Singh, Mohamed Essameldin, Abdelgawad, Zulfiqur, Ali, Jarrod, Bailey, Elisa, Budyn, Prospero, Civita, Martin J D, Clift, John T, Connelly, Samuel, Constant, Marius, Hittinger, Helena, Kandarova, Victoria Rosalind, Kearns, Tony, Kiuru, Tomasz, Kostrzewski, Sebastian, Kress, Victoria Marsh, Durban, Claus-Michael, Lehr, Hayley, McMillan, Julia Katharina, Metz, Vivian, Monteban, Dania, Movia, Catia, Neto, Carla, Owen, Lauri, Paasonen, Kerri Anne, Palmer, Geoffrey John, Pilkington, Karen, Pilkington, Adriele, Prina-Mello, Clive, Roper, Jonathan, Sheard, Sheree, Smith, Janette Ellen, Turner, Ipsita, Roy, Melissa Anne, Tutty, Eirini, Velliou, John Malcolm, Wilkinson
Publikováno v:
Alternatives to laboratory animals : ATLA. 49(3)
Experimental systems that faithfully replicate human physiology at cellular, tissue and organ level are crucial to the development of efficacious and safe therapies with high success rates and low cost. The development of such systems is challenging