Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hayley M. Johnston"'
Publikováno v:
Experimental Hematology. 31:1284-1291
Objective The transmembrane isoform of stem cell factor (tm-SCF) has been implicated in the adhesion of hemopoietic stem cells to the extracellular matrix within the bone marrow microenvironment in vitro. In addition, in vivo SCF has been shown to pl
Autor:
Mira C.P. Liu, Genevieve Whitty, David N. Haylock, Susan K. Nilsson, Kate E. Rutherford, Ivan Bertoncello, Hayley M. Johnston, Brenda Williams, Paul J. Simmons
Publikováno v:
Stem cells (Dayton, Ohio). 25(4)
It is now evident that hemopoietic stem cells (HSC) are located in close proximity to bone lining cells within the endosteum. Accordingly, it is unlikely that the traditional method for harvesting bone marrow (BM) from mice by simply flushing long bo
Publikováno v:
Microscopy and Microanalysis. 11
Autor:
Genevieve Whitty, Ivan Bertoncello, David N. Haylock, Hayley M. Johnston, Susan K. Nilsson, Paul J. Simmons, David T. Denhardt, Brenda Williams, Linda J. Bendall, Ryan J. Webb
Publikováno v:
Blood. 106(4)
Although recent data suggests that osteoblasts play a key role within the hematopoietic stem cell (HSC) niche, the mechanisms underpinning this remain to be fully defined. The studies described herein examine the role in hematopoiesis of Osteopontin
Autor:
Susan K. Nilsson, Tracey Jean Brown, David N. Haylock, Paul J. Simmons, Teresa Occhiodoro, Hayley M. Johnston
Publikováno v:
Blood. 101(3)
The localization of adult hemopoiesis to the marrow involves developmentally regulated interactions between hemopoietic stem cells and the stromal cell–mediated hemopoietic microenvironment. Although primitive hemopoietic cells exhibit a broad repe
Publikováno v:
Blood. 97(8)
The spatial distribution of subpopulations of hemopoietic progenitor cells following syngeneic transplantation was investigated at the single-cell level. The location of infused hemopoietic progenitor cells within the femoral bone marrow of nonablate
Publikováno v:
Blood. 108:708-708
Considerable evidence supports the proposal that the localisation of hemopoiesis to the bone marrow (BM) involves developmentally regulated adhesive interactions between primitive hemopoietic stem cells (HSC) and the hemopoietic microenvironment of t