Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Hayley M McDaid"'
Autor:
June Y Hou, Alicia Rodriguez-Gabin, Leleesha Samaraweera, Rachel Hazan, Gary L Goldberg, Susan Band Horwitz, Hayley M McDaid
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151750 (2016)
Externí odkaz:
https://doaj.org/article/191d07942caa49ad8b0328d48e8538e4
Autor:
June Y Hou, Alicia Rodriguez-Gabin, Leleesha Samaraweera, Rachel Hazan, Gary L Goldberg, Susan Band Horwitz, Hayley M McDaid
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54103 (2013)
While the clinical benefit of MEK inhibitor (MEKi)-based therapy is well established in Raf mutant malignancies, its utility as a suppressor of hyperactive MAPK signaling in the absence of mutated Raf or Ras, is an area of ongoing research. MAPK acti
Externí odkaz:
https://doaj.org/article/e9e92161999f4cda9464fffe33e86bc2
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Panobinostat (pano) is an FDA-approved histone deacetylase inhibitor. There is interest in evaluating alternate dosing schedules and novel combinations of pano for the treatment of upper aerodigestive and lung malignancies; thus we evaluated
Externí odkaz:
https://doaj.org/article/8bf6e32804f94f5480e8b18e2a01b3ef
Publikováno v:
J Nat Prod
Photoaffinity labeling approaches have historically been used in pharmacology to identify molecular targets. This methodology has played a pivotal role in identifying drug-binding domains and searching for novel compounds that may interact at these d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194d02c6dd02db6b2018a97e40486ece
https://doi.org/10.1021/acs.jnatprod.2c00106
https://doi.org/10.1021/acs.jnatprod.2c00106
Autor:
Hayley M. McDaid, Susan Band Horwitz, Gary L. Goldberg, Amos B. Smith, B. Scott Freeze, Lluis Lopez-Barcons, Gloria S. Huang
Purpose: To evaluate the drug combination of discodermolide and Taxol in human ovarian cancer cells and in an in vivo model of ovarian carcinoma.Experimental Design: The combination index method was used to evaluate the interaction of Taxol and disco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3efcd5e6b60c555407d0c28993a16f4
https://doi.org/10.1158/1078-0432.c.6518529.v1
https://doi.org/10.1158/1078-0432.c.6518529.v1
Autor:
Hayley M. McDaid, Susan Band Horwitz, Gary L. Goldberg, Amos B. Smith, B. Scott Freeze, Lluis Lopez-Barcons, Gloria S. Huang
Supplementary Figure S1 from Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-Bearing Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a941d62e8eb71c65b5689aab20f12301
https://doi.org/10.1158/1078-0432.22441470.v1
https://doi.org/10.1158/1078-0432.22441470.v1
Autor:
Susan Band Horwitz, Román Pérez-Soler, Steven Keller, Marie Lia, Aaron Grossman, Lluis Lopez-Barcons, Hayley M. McDaid
Supplementary Figures S1 & S2 from Enhancement of the Therapeutic Efficacy of Taxol by the Mitogen-Activated Protein Kinase Kinase Inhibitor CI-1040 in Nude Mice Bearing Human Heterotransplants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7532a560f8dcc7e137950342abf4139f
https://doi.org/10.1158/0008-5472.22364421
https://doi.org/10.1158/0008-5472.22364421
Autor:
Hayley M. McDaid, Susan Band Horwitz, Roman Pérez-Soler, Steven M. Keller, Lluis Lopez-Barcons, Han-Guang Yan, Chia-Ping Huang Yang, Marie-Emmanuelle Legrier
Supplementary Figure 2 from Targeting Protein Translation in Human Non–Small Cell Lung Cancer via Combined MEK and Mammalian Target of Rapamycin Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3a3928cb8aeefabd4d41decee65650
https://doi.org/10.1158/0008-5472.22370444
https://doi.org/10.1158/0008-5472.22370444
Autor:
Susan Band Horwitz, Román Pérez-Soler, Steven Keller, Marie Lia, Aaron Grossman, Lluis Lopez-Barcons, Hayley M. McDaid
Taxol may contribute to intrinsic chemoresistance by activating the mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) cytoprotective pathway in human cancer cell lines and tumors. We have previously shown addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f971ca16f15024b2bfc540245648840
https://doi.org/10.1158/0008-5472.c.6494184.v1
https://doi.org/10.1158/0008-5472.c.6494184.v1
Autor:
Hayley M. McDaid, Susan Band Horwitz, Roman Pérez-Soler, Steven M. Keller, Lluis Lopez-Barcons, Han-Guang Yan, Chia-Ping Huang Yang, Marie-Emmanuelle Legrier
Lung cancer is a genetically heterogeneous disease characterized by the acquisition of somatic mutations in numerous protein kinases, including components of the rat sarcoma viral oncogene homolog (RAS) and AKT signaling cascades. These pathways inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3d16cadc35a9bb630b4209b8c2da4d
https://doi.org/10.1158/0008-5472.c.6496403
https://doi.org/10.1158/0008-5472.c.6496403