Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hayley L Belnoue‐Davis"'
Autor:
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, Charlotte Moore, Hayley L Belnoue‐Davis, Susanne Flach, John P Lydon, Francesco J DeMayo, Annabelle Lewis, Tjalling Bosse, Ian Tomlinson, David N Church
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract High‐risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the fun
Externí odkaz:
https://doaj.org/article/5c8f6de2c4ae45eeb10187d03d135ae1
Autor:
Ester Gil Vazquez, Nadia Nasreddin, Gabriel N. Valbuena, Eoghan J. Mulholland, Hayley L. Belnoue-Davis, Holly R. Eggington, Ryan O. Schenck, Valérie M. Wouters, Pratyaksha Wirapati, Kathryn Gilroy, Tamsin R.M. Lannagan, Dustin J. Flanagan, Arafath K. Najumudeen, Sulochana Omwenga, Amy M.B. McCorry, Alistair Easton, Viktor H. Koelzer, James E. East, Dion Morton, Livio Trusolino, Timothy Maughan, Andrew D. Campbell, Maurice B. Loughrey, Philip D. Dunne, Petros Tsantoulis, David J. Huels, Sabine Tejpar, Owen J. Sansom, Simon J. Leedham
Publikováno v:
Vasquez, E G, Nasreddin, N, Valbuena, G N, Mulholland, E J, Belnoue-Davis, H L, Eggington, H R, Schenck, R O, Wouters, V M, Wirapati, P, Gilroy, K, Lannagan, T R M, Flanagan, D J, Najumudeen, A K, Omwenga, S, McCorry, A M B, Easton, A, Koelzer, V H, East, J E, Morton, D, Trusolino, L, Maughan, T, Loughrey, M B, Dunne, P D, Tsantoulis, P, Huels, D J, Tejpar, S, Sansom, O J & Leedham, S J 2022, ' Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia ', Cell Stem Cell, vol. 29, no. 8, pp. 1213-1228.e8 . https://doi.org/10.1016/j.stem.2022.07.008
Cell stem cell, 29(8), 1213-1228.e8. Cell Press
Cell stem cell, 29(8), 1213-1228.e8. Cell Press
Intestinal homeostasis is underpinned by LGR5+ve crypt-base columnar stem cells (CBCs), but following injury, dedifferentiation results in the emergence of LGR5-ve regenerative stem cell populations (RSCs), characterized by fetal transcriptional prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e8ae6065d6af4d48e6bf14034d2918
https://pure.qub.ac.uk/en/publications/ebe1f6bb-dff1-49d2-b1ec-2dd3b998e338
https://pure.qub.ac.uk/en/publications/ebe1f6bb-dff1-49d2-b1ec-2dd3b998e338
Autor:
Toshiyasu Suzuki, Anna Kilbey, Rachel A. Ridgway, Hannah Hayman, Ryan Bryne, Nuria Casa Rodríguez, Anastasia Georgakopoulou, Lei Chen, Michael Verzi, David Gay, Ester G. Vázquez, Hayley L. Belnoue-Davis, Kathryn Gilroy, Anne Helene Køstner, Christian Kersten, Chanitra Thuwajit, Ditte Andersen, Robert Wiesheu, Anett Jandke, Natalie Roberts, Karen Blyth, Antonia Roseweir, Simon J. Leedham, Philip D. Dunne, Joanne Edwards, Adrian Hayday, Owen J. Sansom, Seth B. Coffelt
WNT/β-catenin signaling endows cancer cells with proliferative capacity and immune-evasive functions that impair anti-cancer immunosurveillance by conventional, cytoxtoic T cells. However, the impact of dysregulated WNT signalling on unconventional,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda07a1fd5bdde7fa6e738a8786d603a
https://doi.org/10.1101/2022.06.10.495115
https://doi.org/10.1101/2022.06.10.495115
Autor:
Ester Gil Vazquez, Nadia Nasreddin, Gabriel N Valbuena, Eoghan J Mulholland, Hayley L Belnoue-Davis, Holly Eggington, Ryan O Schenck, Valérie M Wouters, Pratyaksha Wirapati, Kathryn Gilroy, Tamsin R M Lannagan, Dustin J Flanagan, Arafath K Najumudeen, Sulochana Omwenga, Amy M B McCorry, Alistair Easton, Viktor H Koelzer, James E East, Dion Morton, Livio Trusolino, Timothy Maughan, Andrew D Campbell, Maurice B Loughrey, Philip D Dunne, Petros Tsantoulis, David J Huels, Sabine Tejpar, Owen Sansom, Simon J Leedham
Intestinal homeostasis is underpinned by LGR5+ve crypt-base columnar stem cells (CBCs), but following injury, dedifferentiation results in the emergence of LGR5-ve regenerative stem cell populations (RSCs), characterised by fetal transcriptional prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbefa25d12c76480d625ba52678c0be8
https://doi.org/10.1101/2022.06.11.495729
https://doi.org/10.1101/2022.06.11.495729
Autor:
Tomas Malinauskas, Gareth Moore, Amalie F. Rudolf, Holly Eggington, Hayley L. Belnoue-Davis, Kamel El Omari, Samuel C. Griffiths, Rachel E. Woolley, Ramona Duman, Armin Wagner, Simon J. Leedham, Clair Baldock, Hilary L. Ashe, Christian Siebold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Twisted gastrulation (TWSG1) is an evolutionarily conserved secreted glycoprotein which controls signaling by Bone Morphogenetic Proteins (BMPs). TWSG1 binds BMPs and their antagonist Chordin to control BMP signaling during embryonic develop
Externí odkaz:
https://doaj.org/article/ddfaa798787944ee8ae8169dabd72ec6