Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hayley J. Bennett"'
A dynamic, spatially periodic, micro-pattern of HES5 underlies neurogenesis in the mouse spinal cord
Autor:
Jochen Kursawe, Nancy Papalopulu, Joshua Hawley, Daniel Han, Hayley J. Bennett, Emma Johns, Ximena Soto, Cerys S Manning, Paul Glendinning, Antony Adamson, Veronica Biga
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 5, Pp n/a-n/a (2021)
Molecular Systems Biology
Molecular Systems Biology
Ultradian oscillations of HES Transcription Factors (TFs) at the single‐cell level enable cell state transitions. However, the tissue‐level organisation of HES5 dynamics in neurogenesis is unknown. Here, we analyse the expression of HES5 ex vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e670fd4e32206840d37c90a1b43f43
https://doi.org/10.1101/2020.08.03.234369
https://doi.org/10.1101/2020.08.03.234369
Publikováno v:
Journal of Biological Chemistry. 282:33326-33335
In this paper, we present the first evidence of a role for the transcriptional regulator SlyA in the regulation of transcription of the Escherichia coli K5 capsule gene cluster and demonstrate, using a combination of reporter gene fusions, DNase I fo
Autor:
Panagiotis Karahalios, Tanya V. Aspinall, James M B Gordon, John Paul Bukowski, Johanna M. Avis, Hayley J. Bennett, Scott C. Walker, David R. Engelke
Publikováno v:
Nucleic Acids Research
Ribonuclease MRP is an endonuclease, related to RNase P, which functions in eukaryotic pre-rRNA processing. In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins. To improve our understanding of subunit roles and enzyme arc
Autor:
Ian Roberts, Abraham L. Sonenshein, David M. Pearce, Hayley J. Bennett, Sarah Glenn, Peter W. Andrew, Clare M. Taylor, Michael Kuhn
Publikováno v:
Molecular Microbiology. 63:1453-1467
Listeria monocytogenes is a Gram-positive intracellular parasite and the causative organism of human listeriosis. In this article we demonstrate that L. monocytogenes encodes a functional member of the CodY family of global regulatory proteins that i
Autor:
Hayley J. Bennett, Ian Roberts
Publikováno v:
FEMS Immunology & Medical Microbiology. 44:163-169
A novel sialic acid-specific lectin has been isolated from Helicobacter pylori lysate using fetuin-agarose affinity chromatography followed by cleavage of the alpha(2,3) and alpha(2,6) linkages of sialic acids using neuraminidase. The protein had a m
Autor:
John Bernard Davenport, Christian Pinali, Andrew W. Trafford, Hayley J. Bennett, Richard F. Collins, Ashraf Kitmitto
Publikováno v:
Bennett, H J, Davenport, J B, Collins, R F, Trafford, A W, Pinali, C & Kitmitto, A 2013, ' Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5) P 3 and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response ', Biochemical Journal, vol. 456, no. 2, pp. 205-217 . https://doi.org/10.1042/BJ20130591
Biochemical Journal
Biochemical Journal
JP2 (junctophilin-2) is believed to hold the transverse tubular and jSR (junctional sarcoplasmic reticulum) membranes in a precise geometry that facilitates excitation–contraction coupling in cardiomyocytes. We have expressed and purified human JP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48652cfdd6ea2f844d836f920507c280
https://www.research.manchester.ac.uk/portal/en/publications/human-junctophilin2-undergoes-a-structural-rearrangement-upon-binding-ptdins345p3-and-the-s101r-mutation-identified-in-hypertrophic-cardiomyopathy-obviates-this-response(dd1f8e66-0c8b-41a5-89d9-a1f74a72583a).html
https://www.research.manchester.ac.uk/portal/en/publications/human-junctophilin2-undergoes-a-structural-rearrangement-upon-binding-ptdins345p3-and-the-s101r-mutation-identified-in-hypertrophic-cardiomyopathy-obviates-this-response(dd1f8e66-0c8b-41a5-89d9-a1f74a72583a).html
Autor:
Christian Pinali, Rachel Walker, Cathy M. Holt, Bernard Davenport, Lucy Murfitt, Ashraf Kitmitto, Mahmoud M Nossier, Nadim Malik, Hayley J. Bennett
Publikováno v:
Heart. 102:A120.1-A120
Introduction A common consequence of coronary artery disease is myocardial infarction (MI). Following an MI a sequence of pathological events occur with necrosis and acute inflammation leading to the formation of a stable fibrous scar. However, altho
Autor:
Mohammad M. Iqbal, Ashraf Kitmitto, Bernard Davenport, Charlotte Bussey, Elizabeth J. Cartwright, Hayley J. Bennett
Publikováno v:
Heart. 102:A123.1-A123
Background Obesity is the leading cause of insulin resistance and a key factor underlying the development of type 2 diabetes. 1 Impaired excitation-contraction (EC) coupling is a hallmark of both type 1 and type 2 diabetes. 2 EC coupling is maintaine
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 457 (2010)
BMC Genomics
BMC Genomics
Background Phosphoinositide metabolism is essential to membrane dynamics and impinges on many cellular processes, including phagocytosis. Modulation of phosphoinositide metabolism is important for pathogenicity and virulence of many human pathogens,
Autor:
Nadim Malik, Rachel E Walker, Laurence J. Allan, Lucy Murfitt, Hayley J. Bennett, Ashraf Kitmitto, J. Bernard Davenport, Christian Pinali, Cathy M. Holt
Publikováno v:
Heart. 101:A94.2-A94
Background Myocardial infarction (MI) is a common cause of death, with approximately 175000 inpatient episodes of acute myocardial infarction in the UK in 2012. Following an MI the loss of cardiac myocytes triggers a remodelling process depositing ex