Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hayley D. McKeen"'
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S3 - PDF file 26K, Figure S3. AD-01 is not cytotoxic. No change in surviving fraction following AD-01 treatment in both MDA-231 and MCF-7 cells was observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fe4f9b732dcda850b879c981eeb059
https://doi.org/10.1158/1078-0432.22448499
https://doi.org/10.1158/1078-0432.22448499
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Table S2 - PDF file 86K, A: Clinical information and the average MFE for every solid primary breast tumour received; tumours of similar grade and status were combined and the average MFE calculated. B: Tumour initiation data following implantation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d00fc63e247f25aa6b096ab5087f046
https://doi.org/10.1158/1078-0432.22448478
https://doi.org/10.1158/1078-0432.22448478
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Supplementary Data Legends - PDF file 63K, Data legends for supplemental figs S1 to S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00517633530e5eda6270f76f4a0a4907
https://doi.org/10.1158/1078-0432.22448484
https://doi.org/10.1158/1078-0432.22448484
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Purpose: FK506-binding protein like (FKBPL) and its peptide derivative, AD-01, have already shown tumor growth inhibition and CD44-dependent antiangiogenic activity. Here, we explore the ability of AD-01 to target CD44-positive breast cancer stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c26b2c05a077ca828a5f0398ae81aa
https://doi.org/10.1158/1078-0432.c.6521412.v1
https://doi.org/10.1158/1078-0432.c.6521412.v1
Autor:
Tracy Robson, David G. Hirst, Helen O. McCarthy, Charles Swanton, Martin O'Rourke, Anita Yakkundi, Andrea Valentine, Christopher Donley, Puthen V. Jithesh, Christopher Byrne, Hayley D. McKeen
Supplementary Figure 3 from FKBPL Regulates Estrogen Receptor Signaling and Determines Response to Endocrine Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d437b39e3a31a7b9a4e60c185cbd20
https://doi.org/10.1158/0008-5472.22384173.v1
https://doi.org/10.1158/0008-5472.22384173.v1
Autor:
Tracy Robson, David G. Hirst, Helen O. McCarthy, Charles Swanton, Martin O'Rourke, Anita Yakkundi, Andrea Valentine, Christopher Donley, Puthen V. Jithesh, Christopher Byrne, Hayley D. McKeen
Supplementary Figure 2 from FKBPL Regulates Estrogen Receptor Signaling and Determines Response to Endocrine Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790c915be948eee5d9ec4482f282d4ff
https://doi.org/10.1158/0008-5472.22384176.v1
https://doi.org/10.1158/0008-5472.22384176.v1
Autor:
Tracy Robson, David G. Hirst, Helen O. McCarthy, Charles Swanton, Martin O'Rourke, Anita Yakkundi, Andrea Valentine, Christopher Donley, Puthen V. Jithesh, Christopher Byrne, Hayley D. McKeen
Supplementary Figure 1 from FKBPL Regulates Estrogen Receptor Signaling and Determines Response to Endocrine Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d58c49271109cd88c307ec919fb3fd
https://doi.org/10.1158/0008-5472.22384179.v1
https://doi.org/10.1158/0008-5472.22384179.v1
Autor:
Tracy Robson, David G. Hirst, Helen O. McCarthy, Charles Swanton, Martin O'Rourke, Anita Yakkundi, Andrea Valentine, Christopher Donley, Puthen V. Jithesh, Christopher Byrne, Hayley D. McKeen
The HSP90 chaperone and immunophilin FKBPL is an estrogen-responsive gene that interacts with estogen receptor α (ERα) and regulates its levels. In this study, we explored the effects of FKBPL on breast cancer proliferation. Breast cancer cells sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34774ac35ce52d383e3599951bea3013
https://doi.org/10.1158/0008-5472.c.6500796
https://doi.org/10.1158/0008-5472.c.6500796
Autor:
Anita Yakkundi, Lynn McCallum, Anthony O'Kane, Hayder Dyer, Jenny Worthington, Hayley D McKeen, Lana McClements, Christopher Elliott, Helen O McCarthy, David G Hirst, Tracy Robson
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55075 (2013)
FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogene
Externí odkaz:
https://doaj.org/article/39619113e6cb4db6bf904cb99dc814a6
Autor:
Helen O. McCarthy, Tracy Robson, Hayley D. McKeen, Laura Nelson, Andrea Valentine, James F. Burrows, Keeva McClelland, Kevin M. Prise, C. Donley, Anita Yakkundi, Puthen V. Jithesh, Lana McClements
Publikováno v:
Oncogene. 33:3441-3450
FKBPL has been implicated in processes associated with cancer, including regulation of tumor growth and angiogenesis with high levels of FKBPL prognosticating for improved patient survival. Understanding how FKBPL levels are controlled within the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62541ca0c5e8c38ef721c46113e3081
https://doi.org/10.1038/onc.2013.306
https://doi.org/10.1038/onc.2013.306