Výsledky vyhledávání - "Hayley Campbell"

Akademický článek

Do fish gut microbiotas vary across spatial scales? A case study of Diplodus vulgaris in the Mediterranean Sea

Autor: Ginevra Lilli, Charlotte Sirot, Hayley Campbell, Fanny Hermand, Deirdre Brophy, Jean-François Flot, Conor T. Graham, Isabelle F. George

Publikováno v: Animal Microbiome, Vol 6, Iss 1, Pp 1-24 (2024)

Abstract Background Biogeography has been linked to differences in gut microbiota in several animals. However, the existence of such a relationship in fish is not clear yet. So far, it seems to depend on the fish species studied. However, most studie

Externí odkaz: https://doaj.org/article/99e549dc1b8940ceb123d604aae91a2c

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Akademický článek

Correction to: Do fish gut microbiotas vary across spatial scales? A case study of Diplodus vulgaris in the Mediterranean Sea

Autor: Ginevra Lilli, Charlotte Sirot, Hayley Campbell, Fanny Hermand, Deirdre Brophy, Jean‑François Flot, Conor T. Graham, Isabelle F. George

Publikováno v: Animal Microbiome, Vol 6, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/958a9b1155cd4b20a2e7acfb0548428e

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Akademický článek

Geographic origin and host’s phylogeny are predictors of the gut mucosal microbiota diversity and composition in Mediterranean scorpionfishes (Scorpaena spp.)

Autor: Ginevra Lilli, Charlotte Sirot, Hayley Campbell, Deirdre Brophy, Conor T. Graham, Isabelle F. George

Publikováno v: Frontiers in Marine Science, Vol 10 (2023)

The gut microbiome holds an important role in the health and homeostasis of fishes. However, despite the large diversity and distribution of this vertebrate group, only the intestinal microbiome of a limited number of freshwater and marine fish speci

Externí odkaz: https://doaj.org/article/792b30ea87bf4570a26fb5d52294e223

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S5. Validation of target genes within pathways shown to be up-regulated by AZD5363 treatment. from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

Autor: Lesley-Ann Martin, Mitch Dowsett, Barry R. Davies, Stephen Johnston, Gianmaria Liccardi, Aradhana Rani, Hayley Campbell, Urszula M. Polanska, Nikiana Simigdala, Aurélie Thuleau, Qiong Gao, Elisabetta Marangoni, Stephanie K. Guest, Sunil Pancholi, Ricardo Ribas

MCF7 and MCF7-LTED cells lines were cultured in DCC {plus minus} AZD5363 and mRNA analysis performed by RT-qPCR. Error bars represent {plus minus} SEM. *p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b6b2ecbae87c4703d69fc67a915231
https://doi.org/10.1158/1535-7163.22502725

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S3. Temporal effect of the combination of AZD5363 with endocrine therapy on PI3K/mTOR/AKT, ER and cell cycle signalling. from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

(A) MCF7 and MCF7-LTED were treated for 1, 8 and 24-hours with the drug combinations indicated (B) T47D, T47D-LTED, ZR75., ZR75-LTED and TamR cell lines were treated for 1-hour as indicated and signalling pathways analysed by immunoblotting. (C) MCF7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb366b71fb3afd3706540444cb035ad
https://doi.org/10.1158/1535-7163.22502731

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S4. Effect of AZD5363 on the expression of endogenous ER genes by qRT-PCR. from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

Cells lines were treated with the combinations stated above for 24-hours, RNA was extracted and cDNA synthetised. mRNA analysis was performed by RT-qPCR using taqman oligos described in the material and methods. Error bars represent {plus minus} SEM.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9844cd451b0204c1bce7c3c54fa7b2e8
https://doi.org/10.1158/1535-7163.22502728

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S2. Formal assessment of AZD5363 combination indices in response to the addition of various endocrine agents. from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

Cell lines were treated as described with GI50 concentrations of each drug alone or in combination, as indicated in the graphs. For Combination Index Tables shown, each graph cells were treated with AZD5363 and a combination of (A) 4-OHT, (B) fulvest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a73b51f9056fa9cee467bb177b374b
https://doi.org/10.1158/1535-7163.22502737

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Data from AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo

PI3K/AKT/mTOR signaling plays an important role in breast cancer. Its interaction with estrogen receptor (ER) signaling becomes more complex and interdependent with acquired endocrine resistance. Targeting mTOR combined with endocrine therapy has sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7077bc7ec2ce97442d2218db500005
https://doi.org/10.1158/1535-7163.c.6537157

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Elektronická kniha

All the Living and the Dead : A Personal Investigation Into the Death Trade

Autor: Hayley Campbell

'A superlative piece of writing... provocative, loving and profound'THE TIMES'Without exaggeration, an awe-inspiring achievement'NIGELLA LAWSON'Moving, funny, and liable to unexpectedly cause me to tear up'NEIL GAIMANAn Irish Times Book of the YearIn

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