Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Hayley A McNamara"'
1
Akademický článek
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
Autor: Camilla R Fisher, Henry J Sutton, Joe A Kaczmarski, Hayley A McNamara, Ben Clifton, Joshua Mitchell, Yeping Cai, Johanna N Dups, Nicholas J D'Arcy, Mandeep Singh, Aaron Chuah, Thomas S Peat, Colin J Jackson, Ian A Cockburn
Publikováno v: PLoS Pathogens, Vol 13, Iss 7, p e1006469 (2017)
The repeat region of the Plasmodium falciparum circumsporozoite protein (CSP) is a major vaccine antigen because it can be targeted by parasite neutralizing antibodies; however, little is known about this interaction. We used isothermal titration cal
Externí odkaz: https://doaj.org/article/7c674fa9b995483c8743396cbc79a755
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2
Akademický článek
Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
Autor: Deepyan Chatterjee, Fiona J. Lewis, Henry J. Sutton, Joe A. Kaczmarski, Xin Gao, Yeping Cai, Hayley A. McNamara, Colin J. Jackson, Ian A. Cockburn
Publikováno v: Cell Reports, Vol 35, Iss 2, Pp 108996- (2021)
Summary: Antibodies targeting the NANP/NVDP repeat domain of the Plasmodium falciparum circumsporozoite protein (CSPRepeat) can protect against malaria. However, it has also been suggested that the CSPRepeat is a decoy that prevents the immune system
Externí odkaz: https://doaj.org/article/eb8c6165353a47159a075cd23c40ac5d
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4
Interactions with Asialo-Glycoprotein Receptors and Platelets Are Dispensable for CD8+ T Cell Localization in the Murine Liver
Autor: James H. O’Connor, Hayley A. McNamara, Yeping Cai, Lucy A. Coupland, Elizabeth E. Gardiner, Christopher R. Parish, Brendan J. McMorran, Vitaly V. Ganusov, Ian A. Cockburn
Publikováno v: The Journal of Immunology. 208:2738-2748
Liver-resident CD8+ T cells can play critical roles in the control of pathogens, including Plasmodium and hepatitis B virus. Paradoxically, it has also been proposed that the liver may act as the main place for the elimination of CD8+ T cells at the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95401ea3e82160a25570fcbba69009d3
https://doi.org/10.4049/jimmunol.2101037
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5
Resident T cells seek the perfect place to work from home
Autor: Hayley A. McNamara, Ian A. Cockburn
Publikováno v: Nature Immunology. 22:1076-1078
CD8+ resident memory T (TRM) cells from different tissues form a heterogeneous population. Transforming growth factor (TGF)-β-independent CD103– TRM cells in the liver retain the ability to move to barrier tissues or return to secondary lymphoid o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06c9995ed6ed4146a052d4bfd50a9f58
https://doi.org/10.1038/s41590-021-01003-2
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6
Splenic Dendritic Cells and Macrophages Drive B Cells to Adopt a Plasmablast Cell Fate
Autor: Hayley A, McNamara, Mireille H, Lahoud, Yeping, Cai, Jessica, Durrant-Whyte, James H, O'Connor, Irina, Caminschi, Ian A, Cockburn
Upon encountering cognate antigen, B cells can differentiate into short-lived plasmablasts, early memory B cells or germinal center B cells. The factors that determine this fate decision are unclear. Past studies have addressed the role of B cell rec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdf3d8ee26ba61189a89b6d95f0b3ed
https://mediatum.ub.tum.de/doc/1657562/document.pdf
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7
Interactions with Asialo-Glycoprotein Receptors and Platelets Are Dispensable for CD8
Autor: James H, O'Connor, Hayley A, McNamara, Yeping, Cai, Lucy A, Coupland, Elizabeth E, Gardiner, Christopher R, Parish, Brendan J, McMorran, Vitaly V, Ganusov, Ian A, Cockburn
Publikováno v: J Immunol
Liver-resident CD8+ T cells can play critical roles in the control of pathogens including Plasmodium and hepatitis B virus. Paradoxically, it has also been proposed that the liver may act as the main place for the elimination of CD8+ T cells at the r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc1416844c9f3b6c8a1963fe7357db19
https://pubmed.ncbi.nlm.nih.gov/35649630
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8
A new method based on the von Mises-Fisher distribution shows that a minority of liver-localized CD8 T cells display hard-to-detect attraction to Plasmodium-infected hepatocytes
Autor: Hayley A. McNamara, Viktor S Zenkov, Ian A. Cockburn, James O’Connor, Vitaly V. Ganusov
Malaria is a disease caused by Plasmodium parasites, resulting in over 200 million infections and 400,000 deaths every year. A critical step of malaria infection is when sporozoites, injected by mosquitoes, travel to the liver and form liver stages.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5d9d9bf89c5a2304dd91c613682251a
https://doi.org/10.1101/2020.12.12.422451
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10
Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
Autor: Colin J. Jackson, Ian A. Cockburn, Hayley A. McNamara, Henry J. Sutton, Joe A. Kaczmarski, Deepyan Chatterjee, Yeping Cai, Fiona J. Lewis, Xin Gao
Publikováno v: Cell Reports, Vol 35, Iss 2, Pp 108996-(2021)
Cell Reports
Summary Antibodies targeting the NANP/NVDP repeat domain of the Plasmodium falciparum circumsporozoite protein (CSPRepeat) can protect against malaria. However, it has also been suggested that the CSPRepeat is a decoy that prevents the immune system
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ac7440ab47cc0879e8347e52c98927
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