Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hayley A Croom"'
Autor:
Dhanasekaran Vijaykrishna, Zhongfang Wang, E. Bridie Clemens, Jodie McVernon, Hayley A Croom, Katherine Kedzierska, Sergio M. Quiñones-Parra, Lukasz Kedzierski
Publikováno v:
Journal of virology. 90(15)
Novel influenza viruses often cause differential infection patterns across different age groups, an effect that is defined as heterogeneous demographic susceptibility. This occurred during the A/H2N2 pandemic, when children experienced higher influen
Autor:
E. Bridie Day, Natasha G. Swan, Katherine Kedzierska, Peter C. Doherty, Stephen J. Turner, Francis R. Carbone, Hayley A Croom, Sophie A. Valkenburg
Publikováno v:
European Journal of Immunology. 40:2470-2481
TCR repertoire diversity can influence the efficacy of CD8(+) T-cell populations, with greater breadth eliciting better protection. We analyzed TCR beta diversity and functional capacity for influenza-specific CD8(+) T cells expressing a single TCR a
Autor:
Warren S. Alexander, Robyn Starr, Anne M Verhagen, Janelle E. Collinge, Hayley A Croom, Morgan E. Wallace, Mhairi J Maxwell, Donald Metcalf, Douglas J. Hilton, Ankita Goradia, Margaret L. Hibbs, Benjamin T. Kile, Sarah Jones
Publikováno v:
The Journal of Immunology. 182:2020-2029
Lyn kinase, a member of the Src family of tyrosine kinases, functions as both a positive and negative regulator of B cell activation. In the absence of Lyn, BCR signaling is unregulated, leading to perturbed B cell development, hyperactive B cells, a
Autor:
Philip Cunningham, Bernard M. Branson, Elizabeth I. M. Johnson, Larissa Doughty, Hayley A Croom, Bruce E. Kemp, Kim Wilson, Kim M. Richards, Elizabeth M. Dax
Publikováno v:
AIDS. 18:2253-2259
Objective: To identify a specific marker of recent HIV-1 infection. Design: The humoral immune response in individuals recently infected with HIV-1 was followed by analysing the antibody isotype-specific response generated to HIV-1 antigens in sequen
Autor:
Hayley A Croom, Lauren A Hatton, Matthew R. Olson, Brendan E. Russ, Stephen J. Turner, Alice E. Denton
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 3 (2012)
Frontiers in Immunology, Vol 3 (2012)
A cardinal feature of adaptive, cytotoxic T lymphocyte (CTL)-mediated immunity is the ability of naïve CTLs to undergo a program of differentiation and proliferation upon activation resulting in the acquisition of lineage-specific T cell functions a
Autor:
Sophie A, Valkenburg, E Bridie, Day, Natasha G, Swan, Hayley A, Croom, Francis R, Carbone, Peter C, Doherty, Stephen J, Turner, Katherine, Kedzierska
Publikováno v:
European journal of immunology. 40(9)
TCR repertoire diversity can influence the efficacy of CD8(+) T-cell populations, with greater breadth eliciting better protection. We analyzed TCR beta diversity and functional capacity for influenza-specific CD8(+) T cells expressing a single TCR a
Autor:
Natasha G. Swan, Peter C. Doherty, Stephen J. Turner, Hayley A Croom, Sophie A. Valkenburg, Alice E. Denton, Katherine Kedzierska, Matthew R. Olson
Publikováno v:
European journal of immunology. 41(3)
The mechanistic basis of memory T-cell development is poorly defined. Phenotypic markers that define precursors at effector stages have been characterized for acute systemic infections with high antigen load. We asked whether such markers can identif
Autor:
Hayley A Croom, Robyn Starr, Douglas J. Hilton, Mark M.W. Chong, Thomas W.H. Kay, Andrew W. Roberts, David J. Curtis, David J. Izon, Warren S. Alexander
Cytokine signals are central to the differentiation of thymocytes and their stepwise progression through defined developmental stages. The intensity and duration of cytokine signals are regulated by the suppressor of cytokine signalling (SOCS) protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3d5325fe460399cd7c52ba444911a4
https://europepmc.org/articles/PMC4291229/
https://europepmc.org/articles/PMC4291229/
Autor:
Susan J. Best, Kim Wilson, Barbara Francis, Elizabeth M. Dax, Elizabeth I. M. Johnson, Hayley A Croom, Kim M. Richards
Publikováno v:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 36(1)
Background Dried blood spots (DBS) provide a convenient method for blood sample collection in many settings where the prevalence of infection with hepatitis C virus (HCV) is increasing. Consequently, HCV assays are required that produce reliable resu
Autor:
Scott Thomson, Sean Emery, C. Jane Dale, Desmond W. Cooper, David B. Boyle, Damian F. J. Purcell, Alistair J. Ramsay, Matthew Law, Rosemary A. Ffrench, Ian A. Ramshaw, Barbara E.H. Coupar, Robert De Rose, Stephen J. Kent, Kim Wilson, Hayley A Croom
Publikováno v:
Vaccine. 23(2)
Induction of HIV-specific T-cell responses by vaccines may facilitate efficient control of HIV. Plasmid DNA vaccines and recombinant fowlpoxvirus (rFPV) vaccines are promising HIV-1 vaccine candidates, although either vaccine alone may be insufficien