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pro vyhledávání: '"Hayla K Sluss"'
Autor:
Heather L Armata, Punita Shroff, David E Garlick, Krista Penta, Andrew R Tapper, Hayla K Sluss
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24813 (2011)
Phosphorylation at murine Serine 18 (human Serine 15) is a critical regulatory process for the tumor suppressor function of p53. p53Ser18 residue is a substrate for ataxia-telangiectasia mutated (ATM) and ATM-related (ATR) protein kinases. Studies of
Externí odkaz:
https://doaj.org/article/14a5b70bb7574353b471ff9ad14aef38
Autor:
Cristina Cellurale, Claire R Weston, Judith Reilly, David S Garlick, D Joseph Jerry, Hayla K Sluss, Roger J Davis
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12469 (2010)
The cJun NH2-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BAL
Externí odkaz:
https://doaj.org/article/e3edcc8710984e838f206fbeb95f0e60
Publikováno v:
Cell. 74:1009-1020
Transforming growth factor beta 1 (TGF beta 1) causes G1 growth arrest and the accumulation of unphosphorylated retinoblastoma protein (Rb) in responsive cells. Cdk4 (cyclin-dependent kinase), a major catalytic subunit of the mammalian D-type G1 cycl