Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hayet Frayssinet"'
Autor:
Hayet Frayssinet, Thomas J. Schnitzer, Michael A. Weber, William B. White, Brigitte Duquesroix, George L. Bakris
Publikováno v:
The American Journal of Cardiology. 107:1338-1345
Nonsteroidal anti-inflammatory drugs are associated with increases in blood pressure (BP), particularly in patients treated with antihypertensive therapy. Naproxcinod is a nitric oxide-donating cyclooxygenase inhibitor in development for osteoarthrit
Autor:
Hayet Frayssinet, Thomas J. Schnitzer, Brigitte Duquesroix, Maarten Beekman, Marc C. Hochberg, Christopher E. Marrero
Publikováno v:
Seminars in Arthritis and Rheumatism. 40:285-297
Comparison of naproxcinod (375 and 750 mg), placebo (up to 13 weeks), and naproxen 500 mg (all bid) for treatment of osteoarthritis (OA) signs and symptoms.A 53-week, randomized, double-blind, parallel-group study. One thousand twenty patients with p
Autor:
Paolo Verdecchia, Thierry Ferreira, Christoph Baerwald, Hayet Frayssinet, Brigitte Duquesroix
Publikováno v:
Arthritis & Rheumatism. 62:3635-3644
Objective To test the superiority of naproxcinod compared with placebo in relieving the signs and symptoms of hip osteoarthritis and to assess the safety of naproxcinod and its effects on blood pressure. Methods In a 13-week, randomized, double-blind
Autor:
Raymond Townsend, Neville Bittar, Jeffrey Rosen, William Smith, Andrea Ramsay, Steven Chrysant, Robert Weiss, Hayet Frayssinet, Brigitte Duquesroix
Publikováno v:
Circulation. 116
Background : Naproxcinod is a first-in-class Cyclooxygenase Inhibiting Nitric Oxide Donator (CINOD) with anti-inflammatory and analgesic properties. Naproxcinod inhibits both COX-1 and COX-2 enzymes. It is well recognized that NSAIDs and coxibs may e