Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Haydn W. R. Williams"'
Autor:
John Scheigetz, Jeffrey D. Chambers, Claude Dufresne, Haydn W. R. Williams, Cheuk K. Lau, Michael A. Bernstein, Jason Crawford
Publikováno v:
ChemInform. 24
Thermolysis of 1-phenyl-4H-1,3,2-benzodioxaborins generated the corresponding ortho-quinone methides, which were found to undergo intermolecular cycloaddition reactions with ethyl vinyl ether, dihy...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1886c907720c5c40f70e8fc6e3278778
https://doi.org/10.1002/chin.199308228
https://doi.org/10.1002/chin.199308228
Autor:
M. Belley, Eugene G. Herold, Marc Labelle, Kathleen M. Metters, E. Grimm, Helene Perrier, Y. B. Xiang, Robert N. Young, D.H. Patrick, Patrick Roy, Lau Cheuk-Kun, John G. DeLuca, Anthony W. Ford-Hutchinson, Daniel Guay, L. Charette, E. Champion, P. Masson, H. Piechuta, A. Lord, Serge Leger, Thomas R. Jones, Jacques-Yves Gauthier, Petpiboon Prasit, Robert Zamboni, Nathalie Ouimet, Yves Leblanc, Claude Dufresne, C.B. Pickett, Zhaoyin Wang, Scott J. Grossman, Richard Frenette, C. S. Mcfarlane, M. McAuliffe, Haydn W. R. Williams, Marc Blouin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1141-1146
A new, potent, orally active leukotriene D 4 receptor antagonist has been discovered. The structure -activity relationship leading to L-695,499 is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24aca7b7ce11d7a67efd5bef3417c939
https://doi.org/10.1016/s0960-894x(00)80635-6
https://doi.org/10.1016/s0960-894x(00)80635-6
Autor:
John Scheigetz, Claude Dufresne, Haydn W. R. Williams, Jeffrey D. Chambers, Cheuk K. Lau, Michael A. Bernstein, Jason Crawford
Publikováno v:
Canadian Journal of Chemistry. 70:1717-1732
Thermolysis of 1-phenyl-4H-1,3,2-benzodioxaborins generated the corresponding ortho-quinone methides, which were found to undergo intermolecular cycloaddition reactions with ethyl vinyl ether, dihydropyran, β-methylstyrene, cyclohexene, and 1-ethoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::506e888e8b6aee859e96c17509a0f59f
https://doi.org/10.1139/v92-216
https://doi.org/10.1139/v92-216
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:297-306
The synthesis of 5-[3-{2-(7-chloroquinolin-2-yl)ethenyl}-phenyl]-8-dimethylcarbamyl-4,6-[6-35S]dithiaoctanoic acid at a specific activity of 1350 Ci/mmol is reported. This compound is a reagent suited for selective affinity binding studies at the LTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9961d556b63ef337265280e21f825405
https://doi.org/10.1002/jlcr.2580280306
https://doi.org/10.1002/jlcr.2580280306
Autor:
Robert Zamboni, Haydn W. R. Williams, Michael A. Bernstein, Robert N. Young, Kathleen M. Metters
Publikováno v:
Bioorganic Chemistry in Healthcare and Technology ISBN: 9781468413564
Leukotrienes D4 (1a) and E4 (1b) are potent contractile substances which have been implicated in the ethiology of human asthma. These leukotrienes exert their effects through interaction with specific receptors on pulmonary smooth muscle and other ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a076b745df83d626b230c468e08cb111
https://doi.org/10.1007/978-1-4684-1354-0_37
https://doi.org/10.1007/978-1-4684-1354-0_37
Autor:
Claude Dufresne, Patrice C. Belanger, Sylvie Tardiff, Cheuk K. Lau, Haydn W. R. Williams, John Scheigetz
Publikováno v:
ChemInform. 21
Reaction of a phenol with an aldehyde in the presence of phenylboronic acid gives a 1,3,2-benzodioxaborin. The latter could be reduced to the corresponding ortho-alkylphenol with tert-butylamine borane in the presence of aluminum chloride. Alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27316dc24f70a9b714ef043b6a3479c
https://doi.org/10.1002/chin.199006106
https://doi.org/10.1002/chin.199006106
Publikováno v:
Canadian Journal of Chemistry. 53:2279-2292
A series of 3-substituted-aminomethy1-3-hydroxy-3,4-dihydro-2H-1,5-benzodioxepins is described. Members of the series constitute a unique class of β-adrenergic stimulants and possess interesting bronchial dilator activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54de5f3615863b003a8a3d0b54e4db81
https://doi.org/10.1139/v75-320
https://doi.org/10.1139/v75-320
Autor:
Haydn W. R. Williams
Publikováno v:
Canadian Journal of Chemistry. 54:3377-3382
The syntheses of 2-isopropylamino-1-(5-hydroxy-4H-pyran-4-on-2-yl)ethanol and the corresponding 4-pyridone and 1-methyl-4-pyridone analogues are described. The selective reduction of an aliphatic nitro group in the presence of a benzyl ether linkage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4feddfe93ce89609f6172d34d9b4c84
https://doi.org/10.1139/v76-485
https://doi.org/10.1139/v76-485
Publikováno v:
Canadian Journal of Chemistry. 61:1383-1386
The resolution of 2-tetrahydrofuran-carboxylic acid and assignment of configuration to the enantiomers are reported. New syntheses of the enantiomers of 2-tetrahydrofurancarboxaldehyde are also described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca125a79ca2ff3c4fb62659f8a60ffd7
https://doi.org/10.1139/v83-242
https://doi.org/10.1139/v83-242
Publikováno v:
Journal of Heterocyclic Chemistry. 13:841-844
The syntheses of some 1,8-naphthyridines substituted in the 6-position with heterocyclic groups are described. A synthetic route to 6-amino-5,7-dimethyl-1,8-naphthyridin-2(1H)one is also presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c0cc4ac7cf359cb8e508dce298e86ab
https://doi.org/10.1002/jhet.5570130429
https://doi.org/10.1002/jhet.5570130429