Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Haydn T. Kissick"'
Autor:
Brendan L.C. Kinney, Brianna Brammer, Vikash Kansal, Connor J. Parrish, Haydn T. Kissick, Yuan Liu, Nabil F. Saba, Zachary S. Buchwald, Mark W. El-Deiry, Mihir R. Patel, Brian J. Boyce, Azeem S. Kaka, Jennifer H. Gross, H. Michael Baddour, Amy Y. Chen, Nicole C. Schmitt
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
T lymphocytes expressing CD57 and lacking costimulatory receptors CD27/CD28 have been reported to accumulate with aging, chronic infection, and cancer. These cells are described as senescent, with inability to proliferate but enhanced cytolytic and c
Externí odkaz:
https://doaj.org/article/3967eb4b36174a4b8c3720cf04420d75
Autor:
Dylan J. Martini, Caroline S. Jansen, Lara R. Harik, Sean T. Evans, T. Anders Olsen, Viraj A. Master, Haydn T. Kissick, Mehmet Asim Bilen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Translocation-associated renal cell carcinoma (tRCC) is a rare, aggressive malignancy that primarily affects children and young adults. There is no clear consensus on the most effective treatment for tRCC and there are no biomarkers of response to tr
Externí odkaz:
https://doaj.org/article/da6ce88eaca443b4b36d698e6a2035ef
Autor:
Dylan J. Martini, T. Anders Olsen, Subir Goyal, Yuan Liu, Sean T. Evans, Benjamin Magod, Jacqueline T. Brown, Lauren Yantorni, Greta Anne Russler, Sarah Caulfield, Jamie M. Goldman, Bassel Nazha, Haydn T. Kissick, Wayne B. Harris, Omer Kucuk, Bradley C. Carthon, Viraj A. Master, Mehmet Asim Bilen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundImmune checkpoint inhibitors (ICI) have revolutionized the treatment of metastatic renal cell carcinoma (mRCC). Biomarkers for mRCC patients treated with ICI are limited, and body composition is underutilized in mRCC. We investigated the as
Externí odkaz:
https://doaj.org/article/9162907753ca46b98f276622972a2ce3
Autor:
Weiwen Zhang, Anna B. Morris, Erica V. Peek, Geeta Karadkhele, Jennifer M. Robertson, Haydn T. Kissick, Christian P. Larsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cytomegalovirus (CMV) is one of the most commonly recognized opportunistic pathogens and remains the most influential known parameter in shaping an individual’s immune system. As such, T cells induced by CMV infection could have a long-term impact
Externí odkaz:
https://doaj.org/article/33a5678f25be4d158c62080fbdbfb451
Autor:
William H. Hudson, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Donald J. McGuire, Rafi Ahmed, Haydn T. Kissick
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show tha
Externí odkaz:
https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd
Autor:
Scott M. Krummey, Anna B. Morris, Jesica R. Jacobs, Donald J. McGuire, Satomi Ando, Katherine P. Tong, Weiwen Zhang, Jennifer Robertson, Sara A. Guasch, Koichi Araki, Christian P. Larsen, Brian D. Evavold, Haydn T. Kissick, Mandy L. Ford
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1282-1291.e5 (2020)
Summary: The identity of CD45 isoforms on the T cell surface changes following the activation of naive T cells and impacts intracellular signaling. In this study, we find that the anti-viral memory CD8+ T pool is unexpectedly comprised of both CD45RB
Externí odkaz:
https://doaj.org/article/d69652ad5ff041889716115077fdfc7b
Autor:
Doan C. Nguyen, Holly C. Lewis, Chester Joyner, Vivien Warren, Haopeng Xiao, Haydn T. Kissick, Ronghu Wu, Jacques Galipeau, F. Eun-Hyung Lee
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Extracellular vesicles (EVs) from bone marrow (BM)-derived mesenchymal stromal cells (BM-MSC) are novel mechanisms of cell-cell communication over short and long distances. BM-MSC have been shown to support human antibody secreting cells (ASC) surviv
Externí odkaz:
https://doaj.org/article/ce20ad55404e4800851981a265d96979
Autor:
Rishi R. Sekar, Claire M. De La Calle, Dattatraya Patil, Sarah A. Holzman, Yoram Baum, Umer Sheikh, Jonathan H. Huang, Adeboye O. Osunkoya, Brian P. Pollack, Haydn T. Kissick, Kenneth Ogan, Viraj A. Master
Publikováno v:
Asian Journal of Urology, Vol 3, Iss 2, Pp 75-81 (2016)
Objective: To examine the prognostic value of tumor major histocompatibility complex I (MHCI) expression on survival and recurrence in patients with clear cell renal cell carcinoma (RCC). Methods: Fifty-three patients that underwent nephrectomy at ou
Externí odkaz:
https://doaj.org/article/d27939e2cb5447cfbf3b606f74c4d7b8
Autor:
Kyu Seo Kim, Rishi R. Sekar, Dattatraya Patil, Michelle A. Dimarco, Haydn T. Kissick, Mehmet A. Bilen, Adeboye O. Osunkoya, Viraj A. Master
Publikováno v:
OncoImmunology, Vol 7, Iss 4 (2018)
Programmed cell death protein 1 (PD-1) immune checkpoint inhibitors have shown activity in patients with advanced renal cell carcinoma (RCC). However, the role of PD-1 expression in tumor-infiltrating lymphocytes (TILs) as a biomarker for poor outcom
Externí odkaz:
https://doaj.org/article/32bf2b5be1794808887723e8989bbbcb
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Advances in molecular pathology have changed the landscape of oncology. The ability to interrogate tissue samples for oncogene amplification, driver mutations, and other molecular alterations provides clinicians with an enormous level of detail about
Externí odkaz:
https://doaj.org/article/a89ba20876ff4a1bb1595c9d80c83354