Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hayden T Pacl"'
Autor:
Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, Sajid Nadeem, Ritesh R. Sevalkar, Kievershen Nargan, Kapongo Lumamba, Threnesan Naidoo, Joel N. Glasgow, Anupam Agarwal, Adrie J. C. Steyn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mycobacterium tuberculosis (Mtb) disrupts glycolytic flux in infected myeloid cells through an unclear mechanism. Flux through the glycolytic pathway in myeloid cells is inextricably linked to the availability of NAD+, which is maintained by
Externí odkaz:
https://doaj.org/article/4e4ad46f3eb246c2ab7a16acbf265d77
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Tuberculosis (TB) was responsible for more deaths in 2019 than any other infectious agent. This epidemic is exacerbated by the ongoing development of multi-drug resistance and HIV co-infection. Recent studies have therefore focused on identifying hos
Externí odkaz:
https://doaj.org/article/761cacf341784afaac3f570449cb15f6
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 177 (2021)
Excessive inflammation and tissue damage are pathological hallmarks of chronic pulmonary tuberculosis (TB). Despite decades of research, host regulation of these clinical consequences is poorly understood. A sustained effort has been made to understa
Externí odkaz:
https://doaj.org/article/5be2bb2524754e6c8eb8e44f2873be29
Autor:
Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, Sajid Nadeem, Ritesh R. Sevalkar, Kierveshan Nargan, Kapongo Lumamba, Threnesan Naidoo, Joel N. Glasgow, Anupam Agarwal, Adrie J. C. Steyn
Mycobacterium tuberculosis (Mtb) disrupts glycolytic flux in infected myeloid cells through an unclear mechanism. Flux through the glycolytic pathway in myeloid cells is inextricably linked to the availability of NAD+, which is maintained by NAD+ sal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cdf01b8274064bd279cb8daf99a352
https://doi.org/10.1101/2022.09.11.507472
https://doi.org/10.1101/2022.09.11.507472
Autor:
Rui Wang, Shannon L. Russell, Kievershen Nargan, Pratistadevi K. Ramdial, John H. Adamson, Adrie J. C. Steyn, Bridgette M. Cumming, Aejazur Rahman, Hayden T Pacl, Threnesan Naidoo, Kelvin W. Addicott
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tuberculosis (TB) is responsible for millions of deaths each year and several billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb modulates host factors, such as endogenous gaseous signalling molecules, to per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ffb8f73d63d5b203fcfa9931e8d7cb
https://doi.org/10.1073/pnas.1919211117
https://doi.org/10.1073/pnas.1919211117
Autor:
Hayden T, Pacl, Jennifer L, Tipper, Ritesh R, Sevalkar, Andrew, Crouse, Camerron, Crowder, Shama, Ahmad, Aftab, Ahmad, Gillian D, Holder, Charles J, Kuhlman, Krishna C, Chinta, Sajid, Nadeem, Todd J, Green, Chad M, Petit, Adrie J C, Steyn, Matthew, Might, Kevin S, Harrod
Publikováno v:
bioRxiv
SummaryThe recent emergence of a novel coronavirus, SARS-CoV-2, has led to the global pandemic of the severe disease COVID-19 in humans. While efforts to quickly identify effective antiviral therapies have focused largely on repurposing existing drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29694efb999bf0d12d02febad87da12f
https://pubmed.ncbi.nlm.nih.gov/34282419
https://pubmed.ncbi.nlm.nih.gov/34282419
Autor:
Hayden T Pacl, Arthur R. Andrews, Juventino Hernandez Rodriguez, Freddie A. Pastrana, Ana J. Bridges, Debbie Gomez, Dennis Burchette, Austin Larey
Publikováno v:
Families, Systems, & Health. 34:367-377
Introduction Type 2 diabetes is often comorbid with internalizing mental health disorders and associated with greater psychiatric treatment resistance. Integrating psychotherapy into primary care can help treat internalizing disorders generally. We e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6aa2c1861f23810004ea6495d3ecb45
https://doi.org/10.1037/fsh0000224
https://doi.org/10.1037/fsh0000224
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 177, p 177 (2021)
Antioxidants, Vol 10, Iss 177, p 177 (2021)
Excessive inflammation and tissue damage are pathological hallmarks of chronic pulmonary tuberculosis (TB). Despite decades of research, host regulation of these clinical consequences is poorly understood. A sustained effort has been made to understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b520564ddefb3741ef295b47b5e54c3d
https://doi.org/10.3390/antiox10020177
https://doi.org/10.3390/antiox10020177
Publikováno v:
Pathogens and Disease
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, encounters variable and hostile environments within the host. A major component of these hostile conditions is reductive and oxidative stresses induced by factors modified by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c4027b11e1085145cc566796c46bed4
https://pubmed.ncbi.nlm.nih.gov/29873719
https://pubmed.ncbi.nlm.nih.gov/29873719
Publikováno v:
Journal of Behavioral Health. :1
Background: Many patients with behavioral health concerns seek services for their problems from primary care providers (PCPs) rather than specialty mental health services. This study investigated whether referrals by PCPs to integrated behavioral hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0482525809630401c476fc4982946300
https://doi.org/10.5455/jbh.20180612104817
https://doi.org/10.5455/jbh.20180612104817