Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hayden, Fisher"'
Autor:
Mohamed Ahmed, Jared Mackenzie, Liku Tezera, Robert Krause, Barry Truebody, Diana Garay-Baquero, Andres Vallejo, Katya Govender, John Adamson, Hayden Fisher, Jonathan W. Essex, Salah Mansour, Paul Elkington, Adrie J. C. Steyn, Alasdair Leslie
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Mycobacterium tuberculosis senses IFN-γ via the membrane protein MmpL10, which results in stimulation of bacterial respiration and virulence gene expression, worsens infection and paradoxically prevents the formation of isoniazid tolerant persisters
Externí odkaz:
https://doaj.org/article/46f025f3b82648ada03fe8702e70e007
Autor:
Franziska Heckel, Anna H. Turaj, Hayden Fisher, H. T. Claude Chan, Michael J. E. Marshall, Osman Dadas, Christine A. Penfold, Tatyana Inzhelevskaya, C. Ian Mockridge, Diego Alvarado, Ivo Tews, Tibor Keler, Stephen A. Beers, Mark S. Cragg, Sean H. Lim
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Agonistic CD27 monoclonal antibodies can be used to enhance the efficacy of depleting antibodies such as anti-CTLA-4 in a colon adenocarcinoma tumour model. CD27 antibody agonism is dependent on isotype and epitope specificity.
Externí odkaz:
https://doaj.org/article/f7e2de2c168f4f2984754369dc482291
Autor:
Christian M. Orr, Hayden Fisher, Xiaojie Yu, Claude H.-T. Chan, Yunyun Gao, Patrick J. Duriez, Steven G. Booth, Isabel Elliott, Tatyana Inzhelevskaya, Ian Mockridge, Christine A. Penfold, Armin Wagner, Martin J. Glennie, Ann L. White, Jonathan W. Essex, Arwen R. Pearson, Mark S. Cragg, Ivo Tews
Publikováno v:
Science Immunology
Antibodies protect from infection, underpin successful vaccines and elicit therapeutic responses in otherwise untreatable cancers and autoimmune conditions. The human IgG2 isotype displays a unique capacity to undergo disulfide shuffling in the hinge
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2021
We present a small (43mm x 24mm x 15mm), off-the-shelf wireless neurostimulator for rodent deep brain stimulation research. Our device enables researchers to wirelessly configure stimulator settings, such as amplitude, pulse width, channel selection,
Autor:
Franziska, Heckel, Anna H, Turaj, Hayden, Fisher, H T Claude, Chan, Michael J E, Marshall, Osman, Dadas, Christine A, Penfold, Tatyana, Inzhelevskaya, C Ian, Mockridge, Diego, Alvarado, Ivo, Tews, Tibor, Keler, Stephen A, Beers, Mark S, Cragg, Sean H, Lim
Publikováno v:
Communications biology. 5(1)
Agonistic CD27 monoclonal antibodies (mAb) have demonstrated impressive anti-tumour efficacy in multiple preclinical models but modest clinical responses. This might reflect current reagents delivering suboptimal CD27 agonism. Here, using a novel pan
Autor:
Jane E. Willoughby, Ivo Tews, Ruth R. French, Chris Orr, Ali Roghanian, Anne White, Stephen A. Beers, Martin J. Glennie, Xiaojie Yu, Mark S. Cragg, Hayden Fisher, Aymen Al-Shamkhani, Osman Dadas
Publikováno v:
Blood Cancer Discovery. 1:IA03-IA03
Agonistic antibodies directed to immunostimulatory receptors are a currently untapped source for immunotherapy. Whereas checkpoint blockers have translated into the clinic, the rules for agonistic antibodies have been more difficult to discern and th
Autor:
Ann L. White, Mark S. Cragg, Tatyana Inzhelevskaya, H.T. Claude Chan, Ivo Tews, Xiaojie Yu, J. Sjef Verbeek, Leon Douglas, Ruth R. French, Martin J. Glennie, Hayden Fisher, Vikki English, Patrick J. Duriez, Jinny Kim, C. Ian Mockridge, Christine A. Penfold
Publikováno v:
Cancer Cell, 37(6), 850-866.e7. CELL PRESS
Cancer Cell
Cancer Cell
Summary Anti-CD40 monoclonal antibodies (mAbs) comprise agonists and antagonists, which display promising therapeutic activities in cancer and autoimmunity, respectively. We previously showed that epitope and isotype interact to deliver optimal agoni
Autor:
Hayden, Fisher, Kate, Knapp
Publikováno v:
Australian nursingmidwifery journal. 21(9)