Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hayden, EY"'
Publikováno v:
Protein science : a publication of the Protein Society, vol 27, iss 8
Yu, X; Hayden, EY; Xia, M; Liang, O; Cheah, L; Teplow, DB; et al.(2018). Surface enhanced Raman spectroscopy distinguishes amyloid B-protein isoforms and conformational states. PROTEIN SCIENCE, 27(8), 1427-1438. doi: 10.1002/pro.3434. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6mx5521q
Yu, X; Hayden, EY; Xia, M; Liang, O; Cheah, L; Teplow, DB; et al.(2018). Surface enhanced Raman spectroscopy distinguishes amyloid B-protein isoforms and conformational states. PROTEIN SCIENCE, 27(8), 1427-1438. doi: 10.1002/pro.3434. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6mx5521q
Amyloid β-protein (Aβ) self-association is one process linked to the development of Alzheimer's disease (AD). Aβ peptides, including its most abundant forms, Aβ40 and Aβ42, are associated with the two predominant neuropathologic findings in AD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ae48530dc6ec4b5a947ba82fc5703fa2
https://escholarship.org/uc/item/6mx5521q
https://escholarship.org/uc/item/6mx5521q
Autor:
Rentsendorj, A, Sheyn, J, Fuchs, D-T, Daley, D, Salumbides, BC, Schubloom, HE, Hart, NJ, Li, S, Hayden, EY, Teplow, DB, Black, KL, Koronyo, Y, Koronyo-Hamaoui, M
Publikováno v:
Rentsendorj, A; Sheyn, J; Fuchs, D-T; Daley, D; Salumbides, BC; Schubloom, HE; et al.(2018). A novel role for osteopontin in macrophage-mediated amyloid-beta clearance in Alzheimer's models. BRAIN BEHAVIOR AND IMMUNITY, 67, 163-180. doi: 10.1016/j.bbi.2017.08.019. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7x21944x
Osteopontin (OPN), a matricellular immunomodulatory cytokine highly expressed by myelomonocytic cells, is known to regulate immune cell migration, communication, and response to brain injury. Enhanced cerebral recruitment of monocytes achieved throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::7a60a25b9b6bdf43d6fd2eae7e8e7c86
http://www.escholarship.org/uc/item/7x21944x
http://www.escholarship.org/uc/item/7x21944x
Publikováno v:
Hayden, EY; Hoi, KK; Lopez, J; Inayathullah, M; Condron, MM; & Teplow, DB. (2017). Identification of key regions and residues controlling A beta folding and assembly. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-10845-6. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3j74j9dh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::08398b4425855ec0fd4d5b7a7fc39144
http://www.escholarship.org/uc/item/3j74j9dh
http://www.escholarship.org/uc/item/3j74j9dh
Publikováno v:
Hayden, EY; Conovaloff, JL; Mason, A; Bitan, G; & Teplow, DB. (2017). Preparation of pure populations of covalently stabilized amyloid beta-protein oligomers of specific sizes. ANALYTICAL BIOCHEMISTRY, 518, 78-85. doi: 10.1016/j.ab.2016.10.026. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9038v8nv
Evidence suggests that amyloid β-protein (Aβ) oligomers may be seminal pathogenic agents in Alzheimer's disease (AD). If so, developing oligomer-targeted therapeutics requires an understanding of oligomer structure. This has been difficult due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::ebc14aa6128775591be10ceb1ed36169
http://www.escholarship.org/uc/item/9038v8nv
http://www.escholarship.org/uc/item/9038v8nv
Publikováno v:
Kim, B; Do, TD; Hayden, EY; Teplow, DB; Bowers, MT; & Shea, J-E. (2016). Aggregation of Chameleon Peptides: Implications of alpha-Helicity in Fibril Formation. JOURNAL OF PHYSICAL CHEMISTRY B, 120(26), 5874-5883. doi: 10.1021/acs.jpcb.6b00830. UCLA: Retrieved from: http://www.escholarship.org/uc/item/46z0d0ht
We investigate the relationship between the inherent secondary structure and aggregation propensity of peptides containing chameleon sequences (i.e., sequences that can adopt either α or β structure depending on context) using a combination of repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::bf774f7f14680529b770b2aad6c7b33b
http://www.escholarship.org/uc/item/46z0d0ht
http://www.escholarship.org/uc/item/46z0d0ht
Autor:
Do, TD, LaPointe, NE, Nelson, R, Krotee, P, Hayden, EY, Ulrich, B, Quan, S, Feinstein, SC, Teplow, DB, Eisenberg, D, Shea, J-E, Bowers, MT
Publikováno v:
Do, TD; LaPointe, NE; Nelson, R; Krotee, P; Hayden, EY; Ulrich, B; et al.(2016). Amyloid beta-Protein C-Terminal Fragments: Formation of Cylindrins and beta-Barrels. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(2), 549-557. doi: 10.1021/jacs.5b09536. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2dz88741
In order to evaluate potential therapeutic targets for treatment of amyloidoses such as Alzheimer's disease (AD), it is essential to determine the structures of toxic amyloid oligomers. However, for the amyloid β-protein peptide (Aβ), thought to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::f175c770dd1fb59b4833533f8f455e5a
http://www.escholarship.org/uc/item/2dz88741
http://www.escholarship.org/uc/item/2dz88741
Autor:
Hayden, EY, Yamin, G, Beroukhim, S, Chen, B, Kibalchenko, M, Jiang, L, Ho, L, Wang, J, Pasinetti, GM, Teplow, DB
Publikováno v:
Hayden, EY; Yamin, G; Yamin, G; Yamin, G; Beroukhim, S; Chen, B; et al.(2015). Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols. Journal of Neurochemistry. doi: 10.1111/jnc.13270. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4h03j1jz
© 2015 International Society for Neurochemistry. Epidemiological evidence that red wine consumption negatively correlates with risk of Alzheimer's disease has led to experimental studies demonstrating that grape seed extracts inhibit the aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::d09a74c4793b4e3e856342c6a6e71a1e
http://www.escholarship.org/uc/item/4h03j1jz
http://www.escholarship.org/uc/item/4h03j1jz
Autor:
Mizwicki, MT, Liu, G, Fiala, M, Magpantay, L, Sayre, J, Siani, A, Mahanian, M, Weitzman, R, Hayden, EY, Rosenthal, MJ, Nemere, I, Ringman, J, Teplow, DB
Publikováno v:
Mizwicki, MT; Liu, G; Fiala, M; Magpantay, L; Sayre, J; Siani, A; et al.(2013). 1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients. Journal of Alzheimer's Disease, 34(1), 155-170. doi: 10.3233/JAD-121735. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9x47s6s2
As immune defects in amyloid-β (Aβ) phagocytosis and degradation underlie Aβ deposition and inflammation in Alzheimer's disease (AD) brain, better understanding of the relation between Aβ phagocytosis and inflammation could lead to promising prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4bc047514930a6f63313740449ec0108
http://www.escholarship.org/uc/item/9x47s6s2
http://www.escholarship.org/uc/item/9x47s6s2
Akademický článek
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Autor:
Mizwicki MT, Liu G, Fiala M, Magpantay L, Sayre J, Siani A, Mahanian M, Weitzman R, Hayden EY, Rosenthal MJ, Nemere I, Ringman J, Teplow DB, Mizwicki, Mathew T, Liu, Guanghao, Fiala, Milan, Magpantay, Larry, Sayre, James, Siani, Avi, Mahanian, Michelle
Publikováno v:
Journal of Alzheimer's Disease; 2013, Vol. 33 Issue 1, p155-170, 16p