NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling.

Autor: Wang S; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Qiao X; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China.; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital & Institute, Beijing, 100142, China., Cui Y; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Liu L; Experimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Cooper T; Experimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Hu Y; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Lin J; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Liu H; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Wang M; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China., Hayball J; Experimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Wang X; Department of Pathology, School of Basic Medical Sciences and Qilu Hospital, Shandong University, Jinan, Shandong Province, China. wangxiao08@sdu.edu.cn.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Aug 06; Vol. 15 (8), pp. 565. Date of Electronic Publication: 2024 Aug 06.

Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx.

Autor: Wang S; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China; Qilu Hospital of Shandong University Spine and Spinal Cord Disease Research Center-ICMRS Collaborating Center for Orthopaedic translational Research, Shandong University, Jinan, Shandong 250012, PR China; Institute of Stomatology, Shandong University, Jinan, Shandong, 250012, PR China; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China., Li W; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China., Zhang P; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, PR China., Wang Z; Qilu Hospital of Shandong University Spine and Spinal Cord Disease Research Center-ICMRS Collaborating Center for Orthopaedic translational Research, Shandong University, Jinan, Shandong 250012, PR China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, PR China., Ma X; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China., Liu C; Department of Orthopaedic Surgery, New York University School of Medicine, New York University Medical Center, New York City, NY, USA., Vasilev K; Future Industries Institute, University of South Australia, Mawson Lakes Campus, Mawson Lakes 5095, Australia; School of Engineering, University of South Australia, Mawson Lakes Campus, Mawson Lakes 5095, Australia., Zhang L; Department of Orthopaedic Surgery, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250012, PR China., Zhou X; Health Management Centre. The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong 250012, PR China., Liu L; Experimental Therapeutics Laboratory, University of South Australia Cancer Research Institute, Adelaide SA 5000, Australia., Hayball J; Experimental Therapeutics Laboratory, University of South Australia Cancer Research Institute, Adelaide SA 5000, Australia; Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide SA 5005, Australia., Dong S; Key Laboratory of Colloid and Interface Chemistry (Shandong University), Ministry of Education, Jinan 250100, PR China., Li Y; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China., Gao Y; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China., Cheng L; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China; Qilu Hospital of Shandong University Spine and Spinal Cord Disease Research Center-ICMRS Collaborating Center for Orthopaedic translational Research, Shandong University, Jinan, Shandong 250012, PR China. Electronic address: chenglei@email.sdu.edu.cn., Zhao Y; Department of Orthopaedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, PR China. Electronic address: lwwzyp@email.sdu.edu.cn.

Publikováno v: Journal of advanced research [J Adv Res] 2022 Nov; Vol. 41, pp. 63-75. Date of Electronic Publication: 2022 Jan 11.

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P-236 New polyclonal antibody therapeutic to treat esophageal adenocarcinoma and Barrett’s esophagus by targeting EPHB4

Autor: Valtanen, P. Garcia, Zhang, J., Scammell, A., Parkinson-Lawrence, E., Michael, M., Hussey, D., Watson, D., Hayball, J.

Publikováno v: In Annals of Oncology July 2020 31 Supplement 3:S167-S167

HPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway.

Autor: Wang M; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China.; Department of Radiation Oncology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China., Qiao X; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China.; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China., Cooper T; Experimental Therapeutics Laboratory, Clinical and Health Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Pan W; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Liu L; Experimental Therapeutics Laboratory, Clinical and Health Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Hayball J; Experimental Therapeutics Laboratory, Clinical and Health Sciences, University of South Australia Cancer Research Institute, Adelaide, SA, Australia., Lin J; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Cui X; Key Laboratory for Experimental Teratology of Chinese Ministry of Education, The Shandong Provincial Key Laboratory of Infection and Immunology, Department of Microbiology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Zhou Y; Key Laboratory for Experimental Teratology of Chinese Ministry of Education, The Shandong Provincial Key Laboratory of Infection and Immunology, Department of Microbiology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Zhang S; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Zou Y; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Zhang R; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China., Wang X; Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan, PR China. wangxiao08@sdu.edu.cn.; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, PR China. wangxiao08@sdu.edu.cn.

Publikováno v: Cell death & disease [Cell Death Dis] 2020 Dec 11; Vol. 11 (12), pp. 1049. Date of Electronic Publication: 2020 Dec 11.